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Valbenazine is a purified isomer of tetrabenazine drug, used to treat tardive dyskinesia which is a nervous system disorder. Dyskinesia refers to involuntary muscle movement that can range from slight tremor to uncontrollable movement of the entire body. Grimacing, tongue movements, lip smacking, lip puckering, pursing of the lips, etc. are the common effects of tardive dyskinesia. Valbenazine drug acts as a vesicular monoamine transporter 2 inhibitor, which is essentially an integral membrane protein, and decreases the level of dopamine in the body. Valbenazine decreases the level of monoamine neurotransmitters by preventing their storage in synaptic vesicles. The effect of this drug has been studied on pregnant women. Subsequently, it is not recommended to pregnant or breastfeeding women. The symptoms of tardive dyskinesia can be severe and are often persistent and irreversible. Both valbenazine and its active metabolite [+]-α-HTBZ have a half-life period of 15-22 hours and Tmax of 0.5 to 1 hr.

Based on class, the valbenazine market can be classified into therapeutic (central nervous system agent), pharmacologic (monoamine depletor), and chemical (benzoquinolizine). Demand for therapeutic valbenazine is on the rise, as its effects on the central nervous system help to cure the disease faster than the other drugs. In terms of end-user, the valbenazine market can be segmented into hospitals, clinical research centers, and academic research organizations. The hospitals segment is expanding rapidly, as these settings are preferred by patients for the treatment of tardive dyskinesia disease or other brain cell disorders. Consumption of alcohol, mental stress, and prolonged usage of neuroleptic drugs are the major factors driving the valbenazine market. However, side effects associated with anticonvulsants and stringent regulations on their usage are some of the factors anticipated to hamper the growth of the market.

North America leads the global valbenazine market because of increasing use of antipsychotic drugs among adults and children in the U.S. This has resulted in the rise in prevalence of tardive dyskinesia. According to the American Academy of Neurology, the newly diagnosed tardive dyskinesia disease incidence was 26,000, and the incidence rate was 10.6 per 100,000 adults in the U.S. in 2016. According to the WHO, neuropsychiatric disorder is the third leading cause of disability-adjusted life years (DALYs) in Europe, and almost 15.2% of the people are affected by it. This creates a demand for drugs such as valbenazine. Asia Pacific is expected to be the fastest growing market for valbenazine drugs, due to increase in consumption of alcohol, mental stress, and growth in population in countries such as India and China. Prevalence of the disease varies according to ethnic ancestry - people with Asian or African inheritance have a 1 in 1,000,000 risk of getting affected. Rise in awareness about mental illness and improvement in the economy are estimated to drive the market for valbenazine drug in Middle East & Africa.

Neurocrine Biosciences Inc. is the only key player in the valbenazine drug market.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Valbenazine Market