Global Pancoast Syndrome Treatment Market Introduction
Pancoast tumors or superior pulmonary sulcus tumors arise from the apical pleuro-pulmonary groove, which is located superior to the first rib. In these tumors, if there is involvement of the surrounding structures such as the cervical paravertebral sympathetic nervous system, brachial plexus, and stellate ganglion, then these are responsible for causing a group of symptoms and signs which are together called Pancoast syndrome. It is characterized by arm pain and ipsilateral shoulder pain, paresis & atrophy of the thenar muscles of the hand, paresthesias, and Horners syndrome (miosis, ptosis, and anhidrosis). Pancoast syndrome is also caused by non-NSCLC (non-small cell lung cancers) tumors, generally small cell lung cancer. Other malignancies such as thyroid carcinomas, primary adenoid cystic carcinomas, lymphomas, or metastasis from any primary carcinoma or even benign tumors at the superior pulmonary sulcus are known for causing Pancoast syndrome. Apical lung infections or abscesses can also be responsible for causing Pancoast syndrome, if there is involvement of the chest wall and the surrounding structures.
Global Pancoast Syndrome Treatment Market - Competitive Landscape
Various premium therapies, specifically in squamous cell and second-line treatments for other types of cancers, which either combine with or replace generic chemotherapies, are being introduced in the market. Moreover, key players are expanding their footprint in the global P syndrome treatment market. For instance, in May 2019, Teva Pharmaceutical Industries Ltd. announced the launch of a generic version of Tarceva (erlotinib) tablets, 150 and 100 mg, in the U.S. Erlotinib tablet, an inhibitor of kinase, is indicated for the treatment of patients having metastatic non-small cell lung cancer (NSCLC), whose tumors have EGFR (epidermal growth factor receptor)) exon 21 (L858R) substitution mutations or exon 19 deletions as detected by an FDA approved test receiving first-line, maintenance, or second or even greater line treatment after the progression following at least one prior regimen of chemotherapy
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Pfizer, Inc. is a global biopharmaceutical company ranked 47th in the ‘Forbes Global 2000 Companies’ list in 2017. It primarily operates through two business segments: Pfizer Innovative Health and Pfizer Essential Health. Pfizer, Inc.’s products have been issued 129 patents in the U.S. and 1,807 patents in the rest of the world. The company offers therapies in multiple therapeutic areas such as endocrinology, neurology, immunology, oncology, HIV, rare diseases, and hematology in over 125 countries.
Novartis AG is a global health care company that develops, manufactures, and provides high-quality drugs and health care services. The company operates through three business segments: innovative medicines, Sandoz, and Alcon. The innovative medicines segment operates through two units: Novartis Pharmaceuticals and Novartis Oncology. Novartis Oncology develops therapeutic treatments in the fields of oncology and rare diseases. It conducts research and development activities through two research organizations: Novartis Institutes for BioMedical Research (NIBR) and Global Drug Development (GDD)
Other key players operating in the global Pancoast syndrome treatment market include Boehringer Ingelheim International GmbH, Eisai Co., Ltd., Eli Lilly and Company, Bristol-Myers Squibb Company, Merck & Co., Inc., F. Hoffmann-La Roche Ltd, AstraZeneca, and Sanofi. These players have adopted strategies such as agreements, partnerships, new product development, and collaborations to gain competitive advantage in the global Pancoast syndrome treatment market
Pancoast Syndrome Treatment Market Dynamics
Rise in prevalence of lung cancer
According to the American lung Association, lung cancer is considered to be the most common cancer in the world, which accounted for 2.1 million new cases and 1.8 million deaths in 2018. According to the National Institutes of Health, the cost of cancer care in the U.S. stood at nearly US$147.5 Bn in 2015, with lunch cancer accounting for US$ 13.4 Bn. The American Cancer Society estimated that around 228,150 new cases of lung cancer (111,710 in women and 116,440 in men) will be reported in the U.S. in 2019, with 142,670 deaths due to lung cancer (66,020 women and 76,650 men).
Genetic Factors and Exposure to Triggers and Carcinogens
According to the Moffitt Cancer Center, carcinogens can be responsible for causing unique biological responses within the body such as changes in the production process of cells in the lungs, which is responsible for causing Pancoast tumor. The slight genetic changes can be triggered by carcinogens in individual tissue cells. These genetic changes can cause the cells to mutate and divide much faster than they usually would. A small group of abnormal cells may initiate to form, after which it can then develop into a Pancoast tumor.
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High Unmet Requirement for Diagnosis
According to the World Health Organization (WHO), every year, cancer accounts for about 8.8 million deaths, mostly in low- and middle-income countries. A large number of cancer cases are diagnosed quite late. Even in countries with optimal health systems and services, a number of cancer cases are diagnosed at an advanced stage, when it becomes harder to treat it. Challenges are higher in low- and middle-income countries, which have lesser access to effective and efficient diagnostic services, including laboratory tests, imaging, and pathology, which are vital in the detection of cancer and eventually plan treatment. Countries also have different capacities for referring cancer patients to the apt level of care.
Global Pancoast Syndrome Treatment Market Segmentation
Based on type, the global Pancoast syndrome treatment market can be segmented into:
- Non-small Cell Lung Cancer (NSCLC)
- Small Cell Lung Cancer (SCLC)
In terms of staging, the global Pancoast syndrome treatment market can be segmented into:
- T3 Tumors
- T4 Tumors
Based on treatment, the global Pancoast syndrome treatment market can be segmented into:
- Radiation Therapy
- Combination Therapy
- Others (targeted therapies, symptom relief)
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
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- Actionable Results to meet all the business priorities
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The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
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- The Middle East and Africa
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Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
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The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
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The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
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