Alpha-2 antiplasmin or plasmin inhibitor, is a type of glycoprotein synthesized by the liver, kidneys and other tissues of the body. It is a serine protease inhibitor which belongs to the Serpin superfamily that acts as the primary inhibitor of the serine protease plasmin. Fibrinolysis occurs due to the conversion of plasminogen to serine protease plasmin by plasminogen activator. Deficiency of Alpha 2 antiplasmin causes a bleeding disorder owing to the increase fibrinolysis. Alpha-2 antiplasmin is the protein responsible for the degradation of fibrin clots and inhibition of fibrinolysis. Congenital deficiency of this glycoprotein leads to internal hemorrhage. Alpha-2 antiplasmin is present in two distinct forms which are as follows:
  • Plasminogen binding
  • Non-plasminogen binding
Alpha 2 antiplasmin is used in various diagnostic technologies such as:
  • Enzyme Linked Immuno-Sorbent Assay (ELISA)
  • Immunohistochemistry – Frozen (IHC-F)
  • Immunohistochemistry – Paraffin (IHC-P)
  • Flow Cytometry
End-users of alpha-2 antiplasmin protein are as follows:
  • Hospitals 
  • Clinics
  • Diagnostic labs
  • Private Labs
The aforementioned end users use this protein in patients with alpha 2 antiplasmin or plasmin inhibitor deficiency especially in patients who have reported to have significant episodes of internal bleeding following a minor trauma and bleeding into the joints.Patients with alpha 2 antiplasmin deficiency often experiences severe medical complications such as:
  • Prolonged bleeding from wounds
  • Increased bleeding after consumption of NSAIDs.
  • Bleeding into joints followed by trauma
  • Increased muscle bleeding, hematomas and bruising
  • Bleeding of gastrointestinal tract
  • Mucosal and CNS bleeding
In the geographical perspective, North America is the leading market owing to the rise in cases of metabolic syndrome. It has been proved that excess levels of alpha-2 antiplasmin is associated with metabolic syndrome and other cardiovascular diseases. Deficiency of alpha-2 antiplasmin protein causes development of atherosclerotic plaque which results in various heart diseases.According to the American Heart Association almost 35% of adults in the U.S. are suffering from metabolic syndrome. Furthermore, the Europe and Asia-Pacific regions are expected to witness increased market traction due to increased incidence rate of cardiovascular diseases.
 
The major factors driving this market are advances in the coagulation testing practices, increasing use of automated instrumentation are rise in cases of cardiovascular diseases. Moreover, factors such as technological advancement in the hospital infrastructures and high adoption rate of preventive diagnostic tests are also expected to drive the market. However, high development costs, need of highly sophisticated instruments and stringent regulatory policies are some of the restraints that could impede the growth of the market globally.
 
Some of the notable players in this industry segment includes Abbott Laboratories, Axis-Shield plc., Bio/Data Corporation, Becton Dickinson, Corgenix Medical Corporation, Helena Laboratories, Instrumentation Laboratory, Roche, Sysmex Corporation and Thermo Fisher Scientific, amongst others.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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