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Opioid Induced Constipation Treatment Market

Opioid Induced Constipation Treatment Market: (Mu-opioid Receptor Antagonist, Chloride Channel Activator, and Others; Solid, Semi-solid, and Liquid): Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015 - 2023

Opioid Induced Constipation Treatment Market: Snapshot

Opioids are prescribed to inhibit non-cancerous chronic pains. Apart from reliving the pain, the drug also results in constipation, which is a side effect. Opioid induced cancer is signified by less than three bowel movements in a week. The constipation, further, requires treatment.

As a result, demand for treatment is increasing vibrantly. The constipation is treated using osmotic, stimulants, and softeners.

To keep up with the demand for opioid induced constipation treatment, manufacturing companies are indulging in research and development activities. Advances in pharmaceutical industry and growing investment on research activities are likely to drive growth of opioid induced constipation treatment market in coming years.

Many global companies are focusing towards development of new medicines for treatment of opioid induced constipation. New medicines are being discovered frequently due to increasing incidence of opioid induced constipation. This, in turn, is anticipated to boost opioid induced constipation treatment market at high growth rate.

Apart from opioid induced constipation treatment, the medicine is also used for colon clearing, stool softening, and bowel movement regulation. High demand for the medicine is also a fuelling factor for growth of the global opioid induced constipation treatment market.

Moreover, rising incidence of headaches and spinal pain as a result of sedentary lifestyle have also accelerated the use of opioids for reducing pain. The factor is also likely to drive the opioid induced constipation treatment market in coming years.

Moreover, growing number of population undergoing surgical procedures has scaled use of pain killers. This has resulted in rise of number of patients with opioid induced constipation. This, in turn, is positively impacting growth of opioid induced constipation treatment market.

However, high cost of these drugs may limit their adoption rate. Lack of awareness and unfavourable reimbursement facilities are some of the factors likely to restrain growth of the market in coming years.

Global Opioid Induced Constipation Treatment Market : Overview

Opioid induced constipation (OIC) market has seen new strides on the back of the growing understanding of its etiology and pharmacology. A large numbers of pharmacological of and non-pharmacological therapies have been used in the prevention and management of OIC. Patients with non-cancer pain are at one of the key target populations. The marked prevalence of opioid-induced constipation has been the key driver for the market. While the figures for the prevalence rates vary in various estimates, most indicate that more than half of non-cancer patients worldwide suffer from the condition. Opioids show deleterious GI consequences, have led to constipation, and other related adverse events such as nausea, bloat, vomiting, abdominal pain, and straining, all which lead to poor quality of life in the affected. In the coming years, as more patients are expected to be diagnosed with OIC, the drug pipeline in the opioid induced constipation market will get a solid boost.

The global opioid-induced constipation treatment market stood at US$ 731.2 million in 2016. Clocking a staggeringly high CAGR of 31.2%, the valuation of the market will climb to US$ 4.8 billion by 2023.

Growing Awareness of Opioid-Induced Constipation Medicines Boosting New Agents

On the basis of drug class, the report segments the opioid induced constipation market into mu-opioid receptor antagonist and chloride channel activator. Of the two, the latter currently leads and held the major share in the opioid-induced constipation treatment market. The array of drugs in the segment are increasingly effective in treating the chronic conditions in IOC.         

However, antagonistic mu-opioid recipients are gathering steam in opioid-induced constipation treatment market, with players in the opioid induced constipation market being successful in improving the efficacy. Most of these drug classes are prescription drugs. In the next few years, both these segments are expected to prosper on the back of growing awareness of opioid-induced constipation medicines among clinicians and the patient population. Patients have been benefitting with the growing array of new agents that act helpful as initial therapies in the opioid induced constipation market.

Consumption of Prescription Opioids and Growing Clinical Evidence Spur Demands in North America

The key regional segments in the opioid-induced constipation treatment market comprise North America, Latin America, Asia Pacific, Europe, and the Middle East and South Africa. Of these, North America has contributed substantial revenues over the past few years. The regional market is projected to generate US$4.05 billion of income from opioid constipation treatment. The demand in North America has been widespread, propelled by substantial numbers of people who take opioid therapies. In many cases, the disease in a growing population in the regions is characterized by chronic non-cancer pain. Moreover, the consumption of prescription opioids in the U.S. is boosting the regional market. Further, a growing body of research has generated considerable clinical evidence in the role of various therapies in managing IOC.

Opioid Induced Constipation Treatment Market

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1. Preface
     1.1. Report Description
     1.2. Research Methodology
     1.3. Market Segmentation

2. Executive Summary
     2.1. Market Snapshot

3. Opioid Induced Constipation Treatment Market - Industry Analysis
     3.1. Introduction
     3.2. Event Impact Analysis 
     3.3. Pain 
     3.4. Market Dynamics
            3.4.1. Drivers
            3.4.2. Restraints
            3.4.3. Opportunities
     3.5. Regulatory Scenario
     3.6. Competitive Landscape
3.6.1. Market Share Analysis of Key Players, 2014 (Value %)
     3.7. Market Attractiveness Analysis of Global Opioid Induced Constipation Treatment Market, by Geography, 2014 

4. Market Segmentation - By Dosage Form of the Drug 
     4.1. Introduction 
     4.2. Global Solid Dosage Form Market Revenue, 2013–2023 (US$ Mn) and Analysis
     4.3. Global Semi-solid Dosage Form Market Revenue, 2013–2023 (US$ Mn) and Analysis
     4.4. Global Liquid Dosage Form Market Revenue, 2013–2023 (US$ Mn) and Analysis

5. Market Segmentation - By Drug Class
     5.1. Introduction 
     5.2. Global Mu Opioid Receptor Antagonist Market Revenue, 2013–2023 (US$ Mn) and Analysis
     5.3. Global Chloride Channel Activator Market Revenue, 2013–2023 (US$ Mn) and Analysis
     5.4. Global Others Market Revenue, 2013–2023 (US$ Mn) and Analysis

6. Pipeline Analysis
     6.1. Overview 
     6.2. Late Stage (Phase III) 
            6.2.1. Naldemedine
            6.2.2. Others
     6.3. Early Stage (Phase I and II) (Qualitative Analysis - Tabular representation)

7. Market Segmentation - By Geography
     7.1. Introduction
     7.2. Global Opioid Induced Constipation Treatment Market Revenue, by Region, 2013–2023 (US$ Mn)
     7.3. North America Opioid Induced Constipation Treatment Market Revenue, by Country, 2013–2023 (US$ Mn)
            7.3.1. U.S. Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.3.2. Canada Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
     7.4. Europe Opioid Induced Constipation Treatment Market – Revenue, by Country, 2013–2023 (US$ Mn)
            7.4.1. U.K. Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.4.2. Germany Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.4.3. France Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.4.4. Rest of Europe Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
     7.5. Asia Pacific Opioid Induced Constipation Treatment Market Revenue, by Country, 2013–2023 (US$ Mn)
            7.5.1. Australia Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.5.2. Japan Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.5.3. South Korea Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.5.4. Rest of APAC Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
     7.6. Latin America Opioid Induced Constipation Treatment Market Revenue, by Country, 2013–2023 (US$ Mn)
            7.6.1. Brazil Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
            7.6.2. Rest of Latin America Opioid Induced Constipation Treatment Market Revenue, 2013–2023, (US$ Mn)
     7.7. Rest of the World Opioid Induced Constipation Treatment Market Revenue, by Country, 2013–2023 (US$ Mn)

8. Recommendations

9. Company Profiles
     9.1. Abbott Laboratories, Inc.
     9.2. AstraZeneca plc
     9.3. Bayer AG
     9.4. Boehringer Ingelheim GmbH
     9.5. C.B. Fleet Company, Inc.
     9.6. COSMO Pharmaceuticals
     9.7. Daewoong Pharmaceutical Co. Ltd. 
     9.8. Takeda Pharmaceutical Co., Ltd.
     9.9. Valeant Pharmaceuticals International, Inc. 

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