Acetohydroxamic acid is a drug used majorly to treat urinary tract infections. Acetohydroxamic acid is derived from hydroxylamine and ethyl acetate and has a molecular structure similar to that of urea. Acetohydroxamic acid has a mild acidic nature and shows ease of solubility in water. Acetohydroxamic acid inhibits the growth of bacterial enzyme urease, which indirectly inhibits the hydrolysis of urea and reduces the production of ammonia in urine infected with urea-splitting organisms substantially. The rise in urinary tract infections associated with proteus mirabilis is anticipated to boost the requirement of acetohydroxamic acid in the forecast period. Additionally, the rise in acute cases of urinary infections in diabetic patients is also anticipated to drive the market for acetohydroxamic acid in the next six years. The market for acetohydroxamic acid is anticipated to be significantly high in developed regions such as North America, chiefly followed by Europe. However, the considerable rise in geriatric population in Asia-Pacific region coupled with significant growth in the number of diabetic patients in this region is expected to be the major upcoming market for acetohydroxamic acid based medicines.
Acetohydroxamic acid chiefly acts as an anti-microbial agent which inhibits the growth of urea splitting bacteria, those are majorly responsible for urinary tract infections. The urea splitting bacteria are responsible for forming struvite stones. These stones are formed in the presence of highly alkaline urine, having a pH value more than 7.2 and in an environment which is rich are in ammonia content. The ammonia is generated through the splitting of urea by colonization with bacteria that produce urease. The struvite stones generally comprise of 5 to 15 percent of the all the urinary tract stones which is a significant amount in urinary tract infections.
Acetohydroxamic acid plays a vital role in decreasing the effect of urea splitting bacteria causing severe urinary tract infections. Additionally, the elderly population, premature infants, infants born with congenital urinary tract malformation, diabetic patients and spinal cord-injured patients are highly susceptible to urinary tract infections. Considerable rise in diabetic patients across the globe is anticipated to drive the demand for acetohydroxamic acid in the next six years. Moreover, the infections associated with urea splitting bacteria being considerably significant in the geriatric population; the global rise in the geriatric population is likely to boost the demand for acetohydroxamic acid in the forecast period.
Currently, the acetohydroxamic acid market is dominated by developed regions such as the U.S. and Europe majorly due to rise in the diabetic and geriatric populations that are highly susceptible to urinary tract infections. The increase in number of elderly population, premature infants, infants born with congenital urinary tract malformation, diabetic patients and spinal cord-injured patients are expected to propel the growth of acetohydroxamic acid market. The market for acetohydroxamic acid is expected to increase in eastern countries in next six years considering the potential benefits associated with of acetohydroxamic acid in treating urinary tract infections. Gradual increase in health awareness across developing regions will help acetohydroxamic acid market to flourish across the globe. Asia-Pacific countries such as China, India, Thailand, Indonesia and other developing countries in RoW are anticipated to be the upcoming market for acetohydroxamic acid.
The potential application of acetohydroxamic acid in medical sector especially treating infections related with urinary tract is anticipated to create a lucrative option for other companies to penetrate in acetohydroxamic acid market. Some of the key players functioning in acetohydroxamic acid industry include Shangrao Newfuture Environment Protection Technology Co. Ltd, Mission Pharmacal Company, etc.
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