Graft is a material used in the treatment of delayed fracture unions, in spinal fusions, to bridge major bone defects or fill cavities created by tumor removal, cysts, or other causes. A synthetically derived material such as hydroxylapatite or calcium sulphate, which is intended to fill, supplement, or reconstruct periodontal or bony defects, is termed as a synthetic graft. This synthetic graft material is composed of biocompatible calcium phosphate materials that are similar to that of the bone and other organ parts and are capable of bonding chemically to the bone and other organ parts of body.

Synthetic materials are produced by sintering or heating up, of chemically formed compounds that subsequently bond together to form a graft. Different procedures are employed in the production of synthetics and many different chemical compounds are utilized, which bind together to form a synthetic graft. The physical properties of synthetics such as composition, morphology, etc., are reproducible, since they are chemically produced and are also part of a controlled manufacturing process. Most synthetics are cleared by the FDA as a bone void filler. Most common materials used in synthetic graft are hydroxyapatite, tricalcium phosphate, biphasic calcium phosphate, calcium sulfate, etc.

The global synthetic graft market is driven by the increase in number of orthopedic surgeries, dental surgeries and facial surgeries, and increasing prevalence of cardiovascular diseases are the major factors contributing to rising demand for synthetic graft. The rising number of bone grafting procedures performed annually, at the global level, has created a shortage of allograft material which has stimulated key players’ interest in developing and supplying synthetic graft to meet the ever increasing demand for graft. Technological advancements in development of synthetic graft and adoption of new technology by key players has further led to the adoption of synthetic graft, as it is associated with benefits such as sterility, reduced morbidity, ease of availability in comparison to allograft or auto graft. A major advantage of employing synthetic graft is that it is not associated with risk of any kind of disease, which has increased the usage of synthetic graft among end-users.

The global synthetic graft market can be segmented into product type, application, end-user, and region. In terms of product, the market can be segmented into cement grafts and ceramic grafts. In terms of application, the synthetic graft market can be segmented into bone graft and vascular graft. The bone graft market can be further sub-segmented into carniomaxillofacial, dental, orthopedics, spinal surgery, and others. The vascular graft segment can be further sub-segmented into coronary artery disease, aneurysm, vascular occlusion, and renal failure. The bone graft segment is likely to dominate the synthetic graft market during forecast period due to rising incidence of accidents, orthopedic surgeries, and spine related surgeries. In terms of end-user, the market can be segmented into hospitals, ambulatory surgical centers, specialty clinics, and others.

In terms of geography, the global synthetic graft market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America held a major share of the synthetic graft market, followed by Europe. Technological advancements in synthetic graft development, increase in healthcare expenditure, and rise in awareness regarding new technology and available products among the end-users are key factors contributing to the expansion of the synthetic graft market in North America. The market in Asia Pacific is expanding rapidly due to rising incidence of medical tourism in the region. Furthermore, factors such availability of high quality treatment at affordable prices as compared to developed nations is a major factor fuelling the expansion of the synthetic graft market.

Key players operating in the global synthetic graft market include Biomatlante,
Graftys, Medtronic Inc, Ceramisys Ltd, NuVasive, Inc., Wright Medical Group N.V., Smith & Nephew Inc, Orthovita, Inc., and Zimmer Biomet and others.

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Synthetic Graft Market