Pyrogens are fever causing substances after administering into the blood. The body ache and rise in body temperature are the notable reactions caused due to injection of unsafe pyrogens in the body. Monocyte activation testing determines the existence of pyrogen and endotoxin substances. The demand for pyrogen testing is currently not limited to the pharmaceutical companies and biological companies but is expanding among other end users too. The global monocyte activation tests market was valued approximately US$ 5.0 Mn in 2016 and is anticipated to register CAGR of over 14.0% from 2017 to 2025 to reach value of approximately US$ 19.0 Mn by 2025.

The global monocyte activation tests market is witnessing continuous innovations in test offerings and wide product portfolio of major as well as local manufacturers. The growth of the global monocyte activation tests market is mostly driven by increasing number of biotechnology and pharmaceutical companies globally, growing research and development investments and increasing new drug approvals. Moreover, additional aspects such as increasing healthcare expenditure, Increase in new innovative drugs and launch of biological products, increase in public and regulatory concerns about product safety support the market growth. Additionally, a proposed ban on animal tests reducing the use of the rabbit pyrogen test is one of the key factors that driving the growth of monocyte activation tests. Increasing contract research organization in the Latin American and Asia Pacific regions coupled with developing healthcare industry in emerging economies define the future landscape of the monocyte activation tests market.

monocyte-activation-test-market.jpg

The global monocyte activation tests market has been categorized on the basis of product type, source, application, end users, and geography. Among product types, the reagent segment accounted for the largest market share in 2016. However, monocyte activation test kits segment is anticipated to grow at a higher growth rate during the forecast period. Continuously rising adoption of superior-quality products newly introduced in the market are expected to drive the MAT kits segment during the forecast period. Among the sources, blood based segment accounted for the largest market share in 2016, blood-based MAT exhibits a natural human reaction to pyrogens and provides a better estimate of pyrogenic activity of preparations than the limulus amebocyte lysate (LAL) or rabbit pyrogen test (RPT). In term of application, medical devices segment accounted the largest market share in 2016. Increasing number of medical devices in market demands for the pyrogen test before approval in the market, this drives the medical devices segment. In end user segment pharmaceutical industry segment accounted for the major share in 2016, while biotechnology industry is anticipated to grow at higher CAGR during the forecast period, owing to factors such as increase in number of research studies in biotech companies to launch various new products likely to increase use of monocyte activation tests kits and reagents.

The global monocyte activation tests market has been divided into five main regions: North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. In terms of revenue, North America is projected to be the dominant market for global monocyte activation tests market in 2016 with more than 30.0% market share owing to many of the leading players located in the region coupled with expanding research and development activities and rising health care awareness. The North America monocyte activation tests market is likely to expand at an average CAGR during the forecast period. Reagent product type segment is estimated to hold the highest share of the North America monocyte activation tests market in 2016. Asia Pacific is expected to be the rapidly developing markets in terms of CAGR during the forecast period. The monocyte activation tests market in Europe is witnessing significant growth, increasing research activities in drug discovery and growing awareness about animal-free endotoxin detection are the key factors supporting the growth of the monocyte activation tests market in Europe. Rapidly growing medical devices, pharmaceutical, and biotechnology industry are primarily driving the growth of the global monocyte activation tests market. In addition, increasing government support and thereby increasing launch of new drugs is fueling the growth of the global monocyte activation tests market.

Key companies operating in the global monocyte activation tests market and profiled in the report include Merck KGaA, Thermo Fisher Scientific, Charles River Laboratories International, Inc., Sanquin, Microcoat Biotechnologie GmbH, Becton, Dickinson and Company, SOLVIAS AG and Lonza Group.

Global Monocyte Activation Tests Market: Overview

This report on monocyte activation tests studies the current as well as future prospects of the market globally. The stakeholders of this report include companies and intermediaries engaged in the manufacture and commercialization of various monocyte activation test products as well as new entrants planning to enter this market. This report comprises an elaborate executive summary along with a market snapshot providing overall information of various segments and sub-segments considered within the scope of the study. This section also provides the overall information and data analysis of the global monocyte activation tests market with respect to the leading market segments based on major products, major source, significant applications, key end-users, and geographies.

The monocyte activation tests market report comprises an elaborate executive summary, which includes a market snapshot that provides information about various segments of the market. It also provides information and data analysis of the global market with respect to the segments based on product, source, application, end-user, and geography. A detailed qualitative analysis of drivers and restraints of the market and opportunities has been provided in the market overview section. In addition, the section comprises competitive matrix and company profiles with business overview to understand the competitive landscape in the market. This section of the report also provides market attractiveness analysis, by geography and market share analysis by key players, thus presenting a thorough analysis of the overall competitive scenario in the global monocyte activation tests market.

Global Monocyte Activation Tests Market: Key Segments

Based on product, the market has been segmented into monocyte activation test kits and reagents. Rising preference for animal-free detection of pyrogens has increased the demand for monocyte activation tests kits and reagents. The market size and forecast for each of these sub-segment have been provided for the period from 2015 to 2025, along with their respective CAGRs for the forecast period from 2017 to 2025, considering 2016 as the base year.

Based on source, the market has been segmented into blood based, peripheral blood mononuclear cell (PBMC) based and cell line based. Factors such as lack of animal usage, reliability, and accuracy are expected to support the growth of the blood-based segment during the forecast period. The market size and forecast for each of these sub-segment have been provided for the period from 2015 to 2025, along with their respective CAGRs for the forecast period from 2017 to 2025, considering 2016 as the base year

Based on application, the market has been segmented into lipid parenteral, dialysis liquids, toxic/immune-modulatory drugs, blood products and medical devices. Various medical devices are launched in the market every year and before the launch, every device needs to undergo pyrogen testing. This factor is responsible for the continuing dominance of the sub-segment. The market size and forecast for each of these sub-segment have been provided for the period from 2015 to 2025, along with their respective CAGRs for the forecast period from 2017 to 2025, considering 2016 as the base year.

Based on end-user, the market has been classified into pharmaceuticals industry, biotechnology industry, medical devices industry and others. Discovery and launch of new products fuel the growth of the pharmaceuticals and biotechnology industry segments, which in turn is projected to boost the growth of the monocyte activation tests market during the forecast period. The market size and forecast for each of these sub-segment have been provided for the period from 2015 to 2025, along with their respective CAGRs for the forecast period from 2017 to 2025, considering 2016 as the base year.

Global Monocyte Activation Tests Market: Regional Outlook

Geographically, the global monocyte activation tests market has been categorized into five major regions and the key countries in the respective region: North America (the U.S., Canada), Europe (the U.K., Germany, France, Spain, Italy, and Rest of Europe), Asia Pacific  (India, China, Japan, Australia & New Zealand and Rest of Asia Pacific), Latin America (Brazil, Mexico, and Rest of Latin America) and Middle East & Africa (South Africa, GCC countries, Israel and Rest of Middle East & Africa). The market size and forecast for each of these regions and the mentioned countries have been provided for the period from 2015 to 2025, along with their respective CAGRs for the forecast period from 2017 to 2025, considering 2016 as the base year. The research study also covers the competitive scenario in these regions.

Companies Mentioned in Report

The report also profiles major players in the global monocyte activation tests market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments. The major players in this market are – Merck KGaA, Thermo Fisher Scientific, Charles River Laboratories International, Inc., Sanquin, Microcoat Biotechnologie GmbH, Becton, Dickinson and Company, SOLVIAS AG, and Lonza Group.

The global monocyte activation tests market is segmented as given below:

  • Global Monocyte Activation Tests Market Revenue, by Product, 2015–2025
    • Monocyte Activation Test Kits
    • Reagents
  • Global Monocyte Activation Tests Market Revenue, by Source, 2015–2025
    • Blood Based
    • Peripheral Blood Mononuclear Bell (PBMC) Based
    • Cell line Based
  • Global Monocyte Activation Tests Market Revenue, by Application, 2015–2025
    • Lipid Parenteral
    • Dialysis Liquids
    • Toxic/immune-modulatory Drugs
    • Blood Products
    • Medical Devices
  • Global Monocyte Activation Tests Market, by End-user
    • Pharmaceuticals Industry
    • Biotechnology Industry
    • Medical Devices Industry
    • Others
  • Global Monocyte Activation Tests Market Revenue, By Geography, 2015–2025
    • North America
      • U.S.
      • Canada
    • Europe
      • Germany
      • U.K.
      • Italy
      • France
      • Spain
      • Rest of Europe
    • Asia Pacific (Except Japan)
      • India
      • China
      • Japan
      • Australia & New Zealand
      • Rest of Asia Pacific
    • Latin America
      • Brazil
      • Mexico
      • Rest of Latin America
    • Middle East & Africa
      • GCC countries
      • South Africa
      • Israel
      • Rest of Middle East & Africa