Liquid Biopsy Market – Snapshot

 Liquid biopsy is a minimally invasive test to assess cancer genetic status based on the analysis of circulating biomarkers that are present in the plasma component of the blood. Liquid biopsies are majorly utilized in the field of oncology. Liquid biopsy can improve and/or resolve several inherent problems found with current cancer treatment, enabling early cancer detection, mutation detection, tumor monitoring during treatment, and recurrence monitoring via a non-invasive blood draw. In addition to being non-invasive, liquid biopsies have the potential to detect cancer before substantial tumor formation, assess multiple mutations within the tumor (reducing heterogeneity concerns), quantitatively monitor treatment progress, and identify new mutations as they emerge as well as monitor for recurrence to detect cancer before imaging-detectable tumor formation or metastasis. In addition to oncology, liquid biopsies are applicable in prenatal testing and transplant care.

liquid biopsy market

The global liquid biopsy market was valued at around US$ 3,883.2 Mn in 2017 and is anticipated to reach US$ 9071.7 Mn by 2026, expanding at a CAGR of 10.1% from 2018 to 2026. Rising prevalence of cancer, increasing applications of liquid biopsy, and intensive research activities being performed to determine the efficacy of liquid biopsy over other diagnostic tests are some factors that are estimated to propel the market during the forecast period.

Presently, R&D on cancer diagnosis is primarily focused toward liquid biopsy. Market players and research institutes are conducting extensive clinical trials to develop highly sensitive liquid biopsy platform. In May 2018, Grail, a U.S.-based biotechnology company, raised US$ 1 Bn in VC funding and embarked on a 120,000-patient study for early breast cancer detection. In January 2018, researchers at Johns Hopkins developed a test called CancerSEEK, which is a non-invasive multianalyte test that analyzes levels of eight cancer proteins and presence of cancer gene mutation in circulating DNA in the blood. The test included more than 1000 patients with nonmetastatic, stages I to III cancers of the ovary, stomach, liver, pancreas, esophagus, lungs, colorectum, and breast. Extensive research on liquid biopsy aimed at promoting early diagnosis in cancer is likely to drive the market for during the forecast period

The liquid biopsy market has been segmented based on application, circulating biomarker, end-user, and region. In terms of application, the oncology segment is estimated to account for a major share of the market. According to the World Health Organization (WHO), cancer accounted for 8.8 million deaths, in 2015. Globally, 1 in 6 deaths is due to cancer. Hence, rise in prevalence of cancer and the need of personalized medicine are expected to augment the segment. Based on circulating biomarkers, the free nucleic acid segment held a major share of the market in 2017. The segment is likely to expand at a considerable growth rate, as compared to other circulating biomarkers, during the forecast period. Introduction of next-generation sequencing and improvements in front-end sample preparation and back-end bioinformatics have led to significant improvement in the sensitivity of cell-free DNA assay, which in turn is driving the segment.

In terms of region, the global liquid biopsy market has been categorized into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Developed regions such as North America and Europe accounted for a leading share of the global liquid biopsy market in 2017. The large base of biopharmaceutical companies and research and academic institutes in these regions has contributed to the leading share of these regions. Moreover, increasing prevalence of cancer and rising geriatric population are further driving the liquid biopsy market in these regions. The market in Asia Pacific is projected to expand at an exponential growth rate, owing to rapidly improving health care facilities in countries such as India, China, South Korea, and Malaysia. China dominated the liquid biopsy market in Asia Pacific, whereas the market in India is anticipated to expand at a significant growth rate during the forecast period. Furthermore, increase in investment by leading market players and hospitals providers is expected to fuel the market in the region. These factors are likely to drive the demand for liquid biopsy in the near future. The market in Latin America and Middle East & Africa is projected to expand at a steady pace during the forecast period.

Prominent players operating in the global liquid biopsy market include Biocept, Inc., MDxHealth, Myriad Genetics, Inc., Bio-Rad Laboratories, QIAGEN, F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Genomic Health, Inc., and Illumina, Inc.

Liquid Biopsy Market: Scope and Methodology

This report on the global liquid biopsy market analyzes the current and future prospects of the market. The report comprises a comprehensive executive summary, including a market snapshot that provides overall information of various segments. The research is a combination of primary and secondary research. Primary research formed the bulk of our research efforts along with information collected from telephonic interviews and interactions via e-mails. Secondary research involved study of company websites, annual reports, press releases, stock analysis presentations, and various international and national databases. The report provides market size in terms of US$ Mn for each segment for the period from 2016 to 2026, considering the macro and micro environmental factors. Growth rates for each segment within the global liquid biopsy market have been determined after a thorough analysis of past trends, demographics, future trends, technological developments, and regulatory requirements.

A detailed qualitative analysis of factors responsible for driving and restraining market growth and future opportunities has been provided in the market overview section. The report also provides insights into the key trends of the liquid biopsy market such as rise in prevalence of cancer, increasing applications of liquid biopsy, advantages of liquid biopsy over tumor biopsy and improvement in health care infrastructure in emerging economies. Key market indicators influencing the global liquid biopsy market including cost constraints and regulatory landscape have been taken into consideration. The report also includes market attractiveness analysis of the major segments that provides a thorough analysis of the overall competitive scenario in the global liquid biopsy market.

Market revenue in terms of US$ Mn for the period between 2016 and 2026 along with the compound annual growth rate (CAGR %) from 2018 to 2026 are provided for all the segments, considering 2017 as the base year. The year-on-year growth of the global liquid biopsy market for each segment is also reflected. Additionally, market-related factors such as favorable reimbursement scenario, expanding applications in chronic diseases and historical year-on-year growth have been taken into consideration while estimating the market size.

Liquid Biopsy Market: Segmentation

Based on application, the global liquid biopsy market has been segmented into oncology, NIPT, transplant diagnostics, and others. In terms of circulating biomarkers, the global liquid biopsy market has been classified into circulating tumor cells (CTC), free nucleic acid, and extracellular vesicles (exosomes). In terms of end-user, the market has been segregated into hospitals, reference laboratories, academic and research institutes, and others.

In terms of region, the global liquid biopsy market has been categorized into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Additionally, the regions have been further segmented into major countries in each of the regions. These include the U.S., Canada, the U.K., Germany, France, Italy, Spain, China, Australia, Japan, India, Brazil, GCC, South Africa, and Mexico.

Liquid Biopsy Market: Competitive Landscape

The report also profiles major players in the liquid biopsy market based on various attributes such as company overview, financial overview, SWOT analysis, key business strategies, product portfolio, and recent developments. Key companies profiled in the report include Biocept, Inc., MDxHealth, Myriad Genetics, Inc., Bio-Rad Laboratories, QIAGEN, F. Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., Genomic Health, Inc., and Illumina, Inc. 

The global liquid biopsy market has been segmented as follows:

Global Liquid Biopsy Market, by Application

  • Oncology
  • NIPT
  • Transplant Diagnostics
  • Others

Global Liquid Biopsy Market, by Circulating Biomarker

  • Circulating Tumor Cells (CTC)
  • Free Nucleic Acid
  • Extracellular vesicles/Exosomes

Global Liquid Biopsy Market, by End-user

  • Hospitals
  • Reference Laboratories
  • Academic and Research Institutes
  • Others

 Global Liquid Biopsy Market, by Region

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • U.K.
    • France
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • Australia & New Zealand
    • Japan
    • China
    • India
    • Rest of Asia pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC
    • South Africa
    • Israel
    • Rest of Middle East & Africa

 

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