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Published Date: 2015-09-02Number of Pages: 87

Bone Grafts and Substitutes Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023

The rising geriatric population and increasing prevalence of bone and joint disorders are the key factors boosting the global bone grafts and substitutes market. Transparency Market Research (TMR) projects the market to rise at a significant pace of 4.5% CAGR between 2015 and 2023, as the number of orthopedic surgeries conducted worldwide increases dramatically. However, incidences of post implantation infection might inhibit the market’s growth to an extent. Stringent regulations implemented to curb such incidences could also limit bone grafts and substitutes sales. Nevertheless, the rising medical tourism in developing economies will create growth opportunities for the market in the forthcoming years.

As per TMR, the global bone grafts and substitutes market stood at US$2.35 bn in 2014 and is expected to reach US$3.48 bn by 2023.

Increasing Arthritis Surgeries will Fuel Demand from Spinal Fusion Segment

By application, the global bone grafts and substitutes market is segmented into long bone, spinal fusion, foot and ankle, joint reconstruction, and craniomaxillofacial. Of these, the spinal fusion application segment held the largest share in the market in 2014. The rising demand for minimally invasive surgeries and the increasing geriatric population around the world are the key factors fuelling demand from this segment. The increasing number of fatal and non-fatal accidents, coupled with the rising arthritis surgeries will also support growth of this segment. As per TMR, the spinal fusion segment is expected to rise at a CAGR of 4.4% between 2014 and 2023.

Besides this, the use of bone grafts and substitutes is also expected to increase in joint reconstruction surgeries. These surgeries are mainly conducted to restore the form and function of the body part affected by infection, tumor, or other diseases. The rising awareness about the effects of joint problems and benefits offered by surgeries in relieving pain will fuel demand from this segment in the forthcoming years.

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North America Dominates Global Market, Asia Pacific to Report High CAGR

Regionally, North America held the largest share in the global bone grafts and substitutes market in 2014. Several leading companies are located in this region, making this region a hotbed of innovation. Launch of novel therapeutics is higher in North America than most other regions, besides which the region is also witnessing an increasing number of road accidents. These are the key factors fuelling sales of bone grafts and substitutes in North America. Furthermore, the increasing geriatric population will fuel the number of orthopedic surgeries conducted in the region. This will in turn bolster demand for bone grafts and substitutes. As per TMR, the North America bone grafts and substitutes market is expected to reach US$1.23 bn by 2023.

In Europe, the bone grafts and substitutes manufacturers will witness rising demand in countries such as Germany, Spain, Italy, France, and the U.K. However, TMR forecasts, the Asia Pacific market to exhibit remarkable growth during the forecast period. The rising medical tourism across countries such as India, China, Malaysia, Singapore, and Thailand, will prove lucrative for the manufacturers of bone grafts and substitutes in the region. Stringent medical device regulations in South Korea, Japan, and China will limit foreign competition, thus bolstering sales opportunities for the domestic players.

Some of the leading players operating in the global bone grafts and substitutes market are Stryker Corporation, Zimmer Inc., Medtronic PLC, Wright Medical Group, Inc., DePuySynthes, AlloSource, and Nuvasive, Inc.

 
Chapter 1 Preface
1.1 Report Description
1.2 Market Segmentation
1.3 Research Methodology
      1.3.1 Secondary Research
      1.3.2 Primary Research
      1.3.3 Data Models
1.4 Assumption
 
Chapter 2 Executive Summary
2.1 Market Snapshot: Global Bone Grafts and Substitutes Market
2.2 Global Bone Grafts and Substitutes Market, by Type, 2014 (USD Million)
2.3 Global Bone Grafts and Substitutes Market, by Application, 2014 (USD Million)
2.4 Comparative Analysis: Global Bone Grafts and Substitutes Market, by Geography, 2014 & 2023 (Value %)
 
Chapter 3 Global Bone Grafts and Substitutes Market Overview
3.1 Overview
3.2 Market Dynamics
      3.2.1 Increasing prevalence of bone and joint disorders drives demand for bone grafts and substitutes
      3.2.2 Rise in the number of orthopedic surgeries
      3.2.3 Growing medical tourism in developing countries is expected to boost market growth
3.3 Market Restraints
      3.3.1 Post implantation infections and ethical issues are expected to hamper market growth
3.4 Market Opportunities
      3.4.1 Large patient pool and rise in disposable income in emerging economies
3.5 Event Impact Analysis: Global Bone Grafts and Substitutes Market
3.6 Pricing Analysis
      3.6.1 Global Pricing Analysis: Global Bone Grafts and Substitutes Market, by Type, 2014 (USD)
3.7 Regulatory Framework
3.8 Porter’s Five Forces Analysis: Global Bone Grafts and Substitutes Market
      3.8.1 Bargaining power of suppliers
      3.8.2 Bargaining power of buyers
      3.8.3 Threat of substitutes
      3.8.4 Threat of new entrants
      3.8.5 Competitive rivalry
3.9 Market Attractiveness Analysis: Global Bone Grafts and Substitutes Market, by Geography
3.10 Competitive Analysis
      3.10.1 Market Share Analysis, by Key Players, 2014 (Value %)
 
Chapter 4 Global Bone Grafts and Substitutes Market, by Types
4.1 Introduction
      4.1.1 Global Bone Grafts and Substitutes Market Revenue, by Type, 2013 – 2023 (USD Million)
4.2 Allografts
      4.2.1 Global Allografts Market Revenue: DBM and Others, by Type, 2013 – 2023 (USD Million)
4.3 Bone Graft Substitutes
      4.3.1 Global Bone Graft Substitutes Market Revenue, Synthetic Bone Grafts, BMP and Others, 2013 – 2023 (USD Million)
 
Chapter 5 Global Bone Grafts and Substitutes Market, by Application
5.1 Overview
      5.1.1 Global Bone Grafts and Substitutes Market, by Application, 2013 – 2023 (USD Million)
5.2 Spinal Fusion
      5.2.1 Global Spinal Fusion Market Revenue, 2013 – 2023 (USD Million)
5.3 Long Bone
      5.3.1 Global Long Bone Market Revenue, 2013 – 2023 (USD Million)
5.4 Foot and Ankle
      5.4.1 Global Foot and Ankle Market Revenue, 2013 – 2023 (USD Million)
5.5 Craniomaxilofacial
      5.5.1 Global Craniomaxilofacial Market Revenue, 2013 – 2023 (USD Million)
5.6 Joint Reconstruction
      5.6.1 Global Joint Reconstruction Market Revenue, 2013 – 2023 (USD Million)
5.7 Dental
      5.7.1 Global Dental Market Revenue, 2013 – 2023 (USD Million)
 
Chapter 6 Global Bone Grafts and Substitutes Market, by Geography
6.1 Introduction
      6.1.1 Global Bone Grafts and Substitutes Market Revenue, by Geography, 2013 – 2023 (USD Million)
6.2 North America (U.S. and Canada)
      6.2.1 North America Bone Grafts and Substitutes Market Revenue: U.S., Canada, 2013 – 2023 (USD Million)
6.3 Europe (U.K., Germany and Rest of Europe)
      6.3.1 Europe Bone Grafts and Substitutes Market Revenue: U.K., Germany, Rest of Europe, 2013 – 2023 (USD Million)
6.4 Asia Pacific (China, Japan and Rest of Asia Pacific)
      6.4.1 Asia Pacific Bone Grafts and Substitutes Market Revenue: China, Japan, Rest of Asia Pacific, 2013 – 2023 (USD Million)
6.5 Latin America (Brazil and Rest of Latin America)
      6.5.1 Latin America Bone Grafts and Substitutes Market Revenue: China, Japan, Rest of Asia Pacific, 2013 – 2023 (USD Million)
6.6 Rest of the World (RoW)
      6.6.1 Global Rest of the World Market Revenue, 2013 – 2023 (USD Million)
 
Chapter 7 Recommendations
7.1 Rigorous research and development (R&D) initiatives
7.2 Investing in emerging economies
7.3 Broadening of distribution network
 
Chapter 8 Company Profile
8.1 AlloSource
      8.1.1 Company Overview
      8.1.2 Financial Overview
      8.1.3 Product Portfolio
      8.1.4 Business Strategy
      8.1.5 Recent Developments
8.2 Baxter International, Inc.
      8.2.1 Company Overview
      8.2.2 Financial Overview
      8.2.3 Product Portfolio
      8.2.4 Business Strategy
      8.2.5 Recent Developments
8.3 DePuy Synthes Companies
      8.3.1 Company Overview
      8.3.2 Financial Overview
      8.3.3 Product Portfolio
      8.3.4 Business Strategy
      8.3.5 Recent Development
8.4 Medtronic plc
      8.4.1 Company Overview
      8.4.2 Financial overview      
      8.4.3 Product Portfolio
      8.4.4 Business Strategy
      8.4.5 Recent Developments
8.5 NuVasive, Inc.
      8.5.1 Company Overview
      8.5.2 Financial Overview
      8.5.3 Product Portfolio
      8.5.4 Business Strategy
      8.5.5 Recent Developments
8.6 Orthofix Holdings, Inc.
      8.6.1 Company Overview
      8.6.2 Financial Overview
      8.6.3 Product Portfolio
      8.6.4 Business Strategy
      8.6.5 Recent Developments
8.7 Stryker Corporation
      8.7.1 Company Overview
      8.7.2 Financial Overview
      8.7.3 Product Portfolio
      8.7.4 Business Strategy
      8.7.5 Recent Developments
8.8 Wright Medical Technology, Inc.
      8.8.1 Company Overview
      8.8.2 Financial Overview
      8.8.3 Product Portfolio
      8.8.4 Business Strategy
      8.8.5 Recent Developments
8.9 Zimmer Biomet Holdings, Inc.
      8.9.1 Company Overview
      8.9.2 Financial Overview
      8.9.3 Product Portfolio
      8.9.4 Business Strategy
      8.9.5 Recent Developments

List of Figures
 
FIG. 1 Global Bone Grafts and Substitutes: Market Segmentation
FIG. 2 Global Bone Grafts and Substitutes Market, 2014 (USD Million)
FIG. 3 Global Bone Grafts and Substitutes Market, by Application, 2014 (USD Million)
FIG. 4 Comparative Analysis: Global Bone Grafts and Substitutes Market, by Geography, 2014 & 2023 (Value %)
FIG. 5 Porter’s Five Forces Analysis: Global Bone Grafts and Substitutes Market
FIG. 6 Market Attractiveness Analysis: Global Bone Grafts and Substitutes Market, by Geography (2014)
FIG. 7 Market Share Analysis of Bone Grafts and Substitutes Market, by Key Players, 2014 (Value %)
FIG. 8 Global Spinal Fusion Revenue, 2013 – 2023 (USD Million)
FIG. 9 Global Long Bone Revenue, 2013 – 2023 (USD Million)
FIG. 10 Global Foot and Ankle Revenue, 2013 – 2023 (USD Million)
FIG. 11 Global Craniomaxilofacial Revenue, 2013 – 2023 (USD Million)
FIG. 12 Global Joint Reconstruction Revenue, 2013 – 2023 (USD Million)
FIG. 13 Global Dental Revenue, 2013 – 2023 (USD Million)
FIG. 14 Global Rest of the World Revenue, 2013 – 2023 (USD Million)
FIG. 15 Baxter International, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 16 Johnson & Johnson: Annual Revenue, 2012–2014 (USD Million)
FIG. 17 Medtronic plc: Annual Revenues, 2012–2014 (USD Million)
FIG. 18 NuVasive, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 19 Orthofix Holdings, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 20 Stryker Corporation: Annual Revenue, 2012–2014 (USD Million)
FIG. 21 Orthofix Holdings, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 22 Zimmer Holdings , Inc.: Annual Revenue, 2012–2014 (USD Million)

List of Tables 
 
FIG. 1 Global Bone Grafts and Substitutes: Market Segmentation
FIG. 2 Global Bone Grafts and Substitutes Market, 2014 (USD Million)
FIG. 3 Global Bone Grafts and Substitutes Market, by Application, 2014 (USD Million)
FIG. 4 Comparative Analysis: Global Bone Grafts and Substitutes Market, by Geography, 2014 & 2023 (Value %)
FIG. 5 Porter’s Five Forces Analysis: Global Bone Grafts and Substitutes Market
FIG. 6 Market Attractiveness Analysis: Global Bone Grafts and Substitutes Market, by Geography (2014)
FIG. 7 Market Share Analysis of Bone Grafts and Substitutes Market, by Key Players, 2014 (Value %)
FIG. 8 Global Spinal Fusion Revenue, 2013 – 2023 (USD Million)
FIG. 9 Global Long Bone Revenue, 2013 – 2023 (USD Million)
FIG. 10 Global Foot and Ankle Revenue, 2013 – 2023 (USD Million)
FIG. 11 Global Craniomaxilofacial Revenue, 2013 – 2023 (USD Million)
FIG. 12 Global Joint Reconstruction Revenue, 2013 – 2023 (USD Million)
FIG. 13 Global Dental Revenue, 2013 – 2023 (USD Million)
FIG. 14 Global Rest of the World Revenue, 2013 – 2023 (USD Million)
FIG. 15 Baxter International, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 16 Johnson & Johnson: Annual Revenue, 2012–2014 (USD Million)
FIG. 17 Medtronic plc: Annual Revenues, 2012–2014 (USD Million)
FIG. 18 NuVasive, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 19 Orthofix Holdings, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 20 Stryker Corporation: Annual Revenue, 2012–2014 (USD Million)
FIG. 21 Orthofix Holdings, Inc.: Annual Revenue, 2012–2014 (USD Million)
FIG. 22 Zimmer Holdings , Inc.: Annual Revenue, 2012–2014 (USD Million)

 
Bones have a natural tendency to heal, however if the defect surpasses a critical size, then bone grafting is the preferred option. Bone grafting is a surgical procedure that replaces the missing or damaged bone by natural or synthetic bone. There are three major types of bone grafts: autografts, allografts, and bone substitutes. Bone grafts and substitutes should be biocompatible, osteoconductive, osteoinductive, structurally similar to bone, easy to use, and cost effective. Autogenous bone grafts contain osteoblast and endosteal osteoprogenitor cells for regenerating the new bone. Although autografts are considered gold standard for bone grafting, major disadvantages associated with autografts are limited supply and high donor site morbidity rate.
 
The bone grafts and substitutes (BGS) market report studies the current scenario as well as future market potential for bone grafts and substitutes globally. The market overview section of the report comprises qualitative analysis of the overall BGS market considering the factors determining the market dynamics such as drivers, restraints, and opportunities, along with Porter’s Five Forces analysis and market attractiveness analysis by geography. In addition, various analyses such as event impact analysis and market share analysis by key players have been provided in the bone graft and substitutes market report. 
 
The global BGS market has been segmented based on type, application, and geography. Based on type, the global BGS market has been categorized into allografts and bone substitutes. The allografts segment has been sub-segmented into demineralized bone matrix (DBM) and others. The bone graft substitutes segment is further segmented into synthetic bone grafts, bone morphogenetic protein (BMP), and others. Based on application, the BGS market has been classified into spinal fusion, long bone, foot and ankle, craniomaxillofacial surgery (CMF), dental, and joint reconstruction. The market for these types and applications has been extensively analyzed on the basis of factors such as product approval date, product demand, sales revenue, geographic presence, and product features. The market size and forecast in terms of revenue (USD million) for each of these segments have been provided for the period from 2013 to 2023, considering 2013 and 2014 as the base years. The report also provides the compound annual growth rate (CAGR) for each segment for the forecast period from 2015 to 2023.
 
Geographically, the BGS market has been classified into five major regions: North America, Europe, Asia Pacific, Latin America, and Rest of the World (RoW). The market size and forecast for each region have been provided for the period from 2013 to 2023, along with the CAGR (%) for the forecast period from 2015 to 2023. 
 
A list of recommendations has also been included for new entrants as well as existing market players to help them establish a strong presence in the market and increase their market shares. The report concludes with the profiles of major players in the global BGS market such as The DePuy Synthes Companies, Zimmer Biomet Holdings, Inc., Baxter International, Inc., Medtronic plc, Stryker Corporation, Wright Medical Technology Inc., AlloSource, NuVasive Inc., and Orthofix Holdings, Inc. The major market players have been assessed on various parameters such as company overview, financial overview, product portfolio, business strategies, and recent developments.
 
The global bone grafts and substitutes market has been segmented as follows:
 
Global Bone Grafts and Substitutes Market, by Type
  • Allografts
    • Demineralised Bone Matrix
    • Others
  • Bone Graft Substitutes
    • Bone Morphogenic Proteins (BMP) 
    • Synthetic Bone Grafts 
    • Others
Global Bone Grafts and Substitutes Market, by Application
  • Spinal Fusion
  • Long Bone
  • Foot and Ankle
  • Craniomaxilofacial
  • Joint Reconstruction
  • Dental
Global Bone Grafts and Substitutes Market, by Geography
  • North America
    • U.S.
    • Canada
  • Europe 
    • U.K.
    • Germany
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • Rest of Asia Pacific 
  • Latin America
    • Brazil
    • Rest of Latin America
  • Rest of the World


 
 
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