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Published Date: 2015-09-02Number of Pages: 87

Bone Grafts and Substitutes Market (Type - Allografts (Demineralised Bone Matrix) and Bone Graft Substitutes (Bone Morphogenic Proteins (BMP) and Synthetic Bone Grafts); Application - Spinal Fusion, Long Bone, Foot and Ankle, Craniomaxilofacial, Joint Reconstruction, and Dental) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2015 - 2023

Global Bone Grafts and Substitutes Market: Snapshot 

World over, the growing number of bone grafting and the use of bone-graft substitutes in various surgical procedures have led to the evolution of the market. The growing number of people with post-traumatic skeletal conditions and the increasing number of patients undergoing orthopedic surgeries have led to pressing need of bone grafts and substitutes in clinical practices. Bone grafting procedures with autograft being the gold standard for bone substitution have gained traction in a number of orthopedic surgeries, especially among geriatric populations in developing and developed regions. In recent years, the market has witnessed stringent regulations to prevent post implantation infections, which is expected to significantly alter the market dynamics in the coming years. In recent years, major advances have been made in bone grafting with the application of tissue-engineered products incorporating stem cells in the process. 

The global market for bone graft and substitutes is projected to expand at a CAGR of 4.5% from 2015 to 2023. Growing at this rate year-over-year, the market is expected to reach US$3.48 bn by the end of the forecast period. 

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Medical Tourism to Offer Lucrative Growth Avenues 

Geographically, the bone grafts and substitutes market is segmented into North America, Europe, Latin America and Asia Pacific. Of these, North America held the major share in 2015. The presence of a large number of regionally and globally prominent companies have kept this regional market at the forefront. This region is continuously witnessing a host of product innovations with the constant launch of novel therapeutics. The growing number of people who suffer from road accidents has fed to the demand for bone grafting procedures.

In addition, the rapidly growing geriatric population has led to the demand for orthopedic surgeries. This has propelled the demand for bone grafts and their substitutes, thereby boosting the market. Opportunities in the North America market for bone grafts and substitutes is projected to reach US$1.23 bn by the end of 2023. 

Europe is a prominent market for bone grafts and substitutes. Countries such as Spain, Germany, Italy, the U.K., and France are providing ample opportunities for manufacturers. On the other hand, the Asia Pacific market for bone grafts and substitutes is anticipated to register significant CAGR during the forecast period. The burgeoning medical tourism in countries such as China, India, Malaysia, Thailand, and Singapore is expected to provide lucrative growth avenues for market players in this region. The stricter implementation of regulatory requirements by numerous medical device manufacturers in countries such as Japan, South Korea, and China is expected to positively impact the regional market. 

On the basis of application, the global market for bone grafts and substitutes is segmented into spinal fusion, long bone, joint reconstruction, craniomaxillofacial, and foot and ankle. Among these, the application of bone grafts and substitutes in spinal fusion accounted for the largest share in 2014. The growth in the segment is attributed to the rising demand for minimally invasive surgeries and the growing number of geriatric people with bone defects. Furthermore, the growing number of accidents and the rising cases of arthritis surgeries are key factors boosting the spinal infusion segment. The spinal fusion segment is projected to expand at a CAGR of 4.4% during 2015–2023. 

The extensive application of allograft bones in the reconstructive surgery of knee, hip, and long bones affected by tumors and traumatic injuries have substantially fueled the spinal fusion segment. 

Based on type, the bone grafts and substitutes market is broadly segmented into allografts and bone graft substitutes. The bone graft substitutes is further bifurcated into bone morphogenic proteins (BMP) and synthetic bone grafts. Bone allografts are gaining prominence in correcting various types of bone defects and have several advantages. However, their use may be limited by their availability and their role in supposedly transmitting infectious agents. 

Some of the key companies operating in the bone grafts and substitute market include Nuvasive, Inc., DePuy Synthes, Wright Medical Group, Inc., Medtronic, and Zimmer Biomet.

 
Bones have a natural tendency to heal, however if the defect surpasses a critical size, then bone grafting is the preferred option. Bone grafting is a surgical procedure that replaces the missing or damaged bone by natural or synthetic bone. There are three major types of bone grafts: autografts, allografts, and bone substitutes. Bone grafts and substitutes should be biocompatible, osteoconductive, osteoinductive, structurally similar to bone, easy to use, and cost effective. Autogenous bone grafts contain osteoblast and endosteal osteoprogenitor cells for regenerating the new bone. Although autografts are considered gold standard for bone grafting, major disadvantages associated with autografts are limited supply and high donor site morbidity rate.
 
The bone grafts and substitutes (BGS) market report studies the current scenario as well as future market potential for bone grafts and substitutes globally. The market overview section of the report comprises qualitative analysis of the overall BGS market considering the factors determining the market dynamics such as drivers, restraints, and opportunities, along with Porter’s Five Forces analysis and market attractiveness analysis by geography. In addition, various analyses such as event impact analysis and market share analysis by key players have been provided in the bone graft and substitutes market report. 
 
The global BGS market has been segmented based on type, application, and geography. Based on type, the global BGS market has been categorized into allografts and bone substitutes. The allografts segment has been sub-segmented into demineralized bone matrix (DBM) and others. The bone graft substitutes segment is further segmented into synthetic bone grafts, bone morphogenetic protein (BMP), and others. Based on application, the BGS market has been classified into spinal fusion, long bone, foot and ankle, craniomaxillofacial surgery (CMF), dental, and joint reconstruction. The market for these types and applications has been extensively analyzed on the basis of factors such as product approval date, product demand, sales revenue, geographic presence, and product features. The market size and forecast in terms of revenue (USD million) for each of these segments have been provided for the period from 2013 to 2023, considering 2013 and 2014 as the base years. The report also provides the compound annual growth rate (CAGR) for each segment for the forecast period from 2015 to 2023.
 
Geographically, the BGS market has been classified into five major regions: North America, Europe, Asia Pacific, Latin America, and Rest of the World (RoW). The market size and forecast for each region have been provided for the period from 2013 to 2023, along with the CAGR (%) for the forecast period from 2015 to 2023. 
 
A list of recommendations has also been included for new entrants as well as existing market players to help them establish a strong presence in the market and increase their market shares. The report concludes with the profiles of major players in the global BGS market such as The DePuy Synthes Companies, Zimmer Biomet Holdings, Inc., Baxter International, Inc., Medtronic plc, Stryker Corporation, Wright Medical Technology Inc., AlloSource, NuVasive Inc., and Orthofix Holdings, Inc. The major market players have been assessed on various parameters such as company overview, financial overview, product portfolio, business strategies, and recent developments.
 
The global bone grafts and substitutes market has been segmented as follows:
 
Global Bone Grafts and Substitutes Market, by Type
  • Allografts
    • Demineralised Bone Matrix
    • Others
  • Bone Graft Substitutes
    • Bone Morphogenic Proteins (BMP) 
    • Synthetic Bone Grafts 
    • Others
Global Bone Grafts and Substitutes Market, by Application
  • Spinal Fusion
  • Long Bone
  • Foot and Ankle
  • Craniomaxilofacial
  • Joint Reconstruction
  • Dental
Global Bone Grafts and Substitutes Market, by Geography
  • North America
    • U.S.
    • Canada
  • Europe 
    • U.K.
    • Germany
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • Rest of Asia Pacific 
  • Latin America
    • Brazil
    • Rest of Latin America
  • Rest of the World


 
 
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