Over the past couple of decades, the prevalence of degenerative intervertebral disc disease has witnessed a notable spike due to which, the demand for prosthetic disc nucleus has increased worldwide– a major factor that is expected to drive the global prosthetic disc nucleus market during the forecast period. The demand for advanced back treatments is on the rise due to increasing sedentary lifestyle, lack of exercise, and posture-related issues. In recent years, due to the surging awareness and high efficacy of minimally invasive procedures, consumer demand has increased at a rapid pace, thus boosting the growth of the global prosthetic disc nucleus market.
The arrival of nucleus pulposus (NP) replacement has emerged as an ideal minimally invasive alternative to discectomy with fusion, and it plays a key role in preventing adjacent level degenerative disease. A number of NP replacement materials are under review by the scientific and research community and has shown immense promise due to which, the overall prospects of prosthetic disc nucleus offer a positive outlook. Advancements in gene therapy, tissue engineering, and other medical spheres are also likely to propel the prosthetic disc nucleus market during the forecast period.
At the back of these factors, the global prosthetic disc nucleus market is on course to reach ~US$ 195 Mn by the end of 2030.
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The prevalence of lower back pain is one of the major problem in individuals of all age groups. While in most cases, back pain can be treated using conventional physiotherapy and medication, early intervention for the treatment of degenerative disc diseases is imperative. Over the past couple of decades, minimally invasive procedures and regenerative medicines have garnered immense popularity and the adoption is expected to further rise in comparison with existing surgical procedures. Advancements in cell-based, bio-molecular, and gene therapies are expected to provide a plethora of opportunities to the players involved in the current prosthetic disc nucleus market.
The promise offered by non-invasive therapies, including prosthetic disc nucleus, is set to fuel the overall growth of the global prosthetic disc nucleus market during assessment period. However, high costs of implants and overall procedure are expected to pose as a barrier to market growth.
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Major players involved in the current prosthetic disc nucleus market landscape are increasingly focusing on attaining regulatory approval and launching new products to gain a competitive edge in the current market for prosthetic disc nucleus. In addition, market players are also expected to focus on mergers & acquisitions to expand their market presence.
For instance, in March 2018, Orthofix International N.V. announced that the company had acquired Spinal Kinetics, Inc.– the move is expected to expand the product portfolio of the company. In November 2018, Xian Jansesen and Ali Health entered into a strategic alliance that will establish a cutting-edge model for Internet health services.
The onset of the novel COVID-19 pandemic is projected to have a strong impact on the overall growth of the global prosthetic disc nucleus market in 2020. Due to stringent lockdowns, restrictions on trade and transportation and increasing focus on curbing the spread of the novel COVID-19 infection, the demand for steeply priced prosthetic disc nucleus has witnessed a decline in 2020. Furthermore, supply chains of raw materials have been severely disrupted due to the transportation restrictions, thereby impacting the overall production of prosthetic disc nucleus. Due to this, the market growth is likely to remain slower than initial projections.
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Analysts’ Viewpoint
The global prosthetic disc nucleus market is expected to expand at an impressive CAGR of ~8% during the forecast period. The market growth will be driven by the increasing prevalence of degenerative back diseases, advancements in gene therapies, tissue engineering, and cell therapy, and research and development activities. Research and development activities will play a key role in the overall development of the global prosthetic disc nucleus market. Market players should focus on mergers & acquisitions and product launch to gain a competitive edge in the current prosthetic disc nucleus market landscape.
Prosthetic Disc Nucleus Market – Segmentation
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Prosthetic disc nucleus (PDN) Market is on course to reach ~US$ 195 Mn by the end of 2030
Prosthetic disc nucleus (PDN) Market is anticipated to expand at a CAGR of ~8% from 2020 to 2030
Prosthetic disc nucleus (PDN) Market is driven by rise in prevalence of spine disorders across globe, increase in global geriatric population, and high demand for minimally invasive surgeries across the globe
North America dominated the global prosthetic disc nucleus market, followed by Europe
Key players operating in the global prosthetic disc nucleus market include Stryker Corporation, Zimmer Biomet Holdings, Inc, DePuy Synthes (Johnson & Johnson), NuVasive, Inc, and Orthofix International N.V.
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Prosthetic Disc Nucleus Market
4. Market Overview
4.1. Introduction
4.1.1. Market Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Prosthetic Disc Nucleus Market Analysis and Forecast, 2018–2030
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Disease Prevalence and Incidence Rate of Degenerative Spine Diseases
5.2. COVID-19 Pandemics Impact on Global Prosthetic Disc Nucleus Market
6. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by Surgery Type
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
6.3.1. Minimally Invasive Spine Surgery
6.3.2. Open Spine Surgery
6.4. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type
7. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by End-user
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
7.3.1. Hospitals
7.3.2. Ambulatory Surgery Centers
7.3.3. Others
7.4. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user
8. Global Prosthetic Disc Nucleus Market Analysis and Forecast, by Region
8.1. Key Findings
8.2. Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Region
8.2.1. North America
8.2.2. Europe
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Region
9. North America Prosthetic Disc Nucleus Market Analysis and Forecast
9.1. Introduction
9.1.1. Key Findings
9.2. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
9.2.1. Minimally Invasive Spine Surgery
9.2.2. Open Spine Surgery
9.3. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
9.3.1. Hospitals
9.3.2. Ambulatory Surgery Centers
9.3.3. Others
9.4. North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country, 2018–2030
9.4.1. U.S.
9.4.2. Canada
9.5. North America Prosthetic Disc Nucleus Market Attractiveness Analysis
9.5.1. By Surgery Type
9.5.2. By End-user
9.5.3. By Country
10. Europe Prosthetic Disc Nucleus Market Analysis and Forecast
10.1. Introduction
10.1.1. Key Findings
10.2. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
10.2.1. Minimally Invasive Spine Surgery
10.2.2. Open Spine Surgery
10.3. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
10.3.1. Hospitals
10.3.2. Ambulatory Surgery Centers
10.3.3. Others
10.4. Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
10.4.1. Germany
10.4.2. U.K.
10.4.3. France
10.4.4. Spain
10.4.5. Italy
10.4.6. Rest of Europe
10.5. Europe Prosthetic Disc Nucleus Market Attractiveness Analysis
10.5.1. By Surgery Type
10.5.2. By End-user
10.5.3. By Country/Sub-region
11. Asia Pacific Prosthetic Disc Nucleus Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
11.2.1. Minimally Invasive Spine Surgery
11.2.2. Open Spine Surgery
11.3. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
11.3.1. Hospitals
11.3.2. Ambulatory Surgery Centers
11.3.3. Others
11.4. Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
11.4.1. China
11.4.2. India
11.4.3. Japan
11.4.4. Australia & New Zealand
11.4.5. Rest of Asia Pacific
11.5. Asia Pacific Prosthetic Disc Nucleus Market Attractiveness Analysis
11.5.1. By Surgery Type
11.5.2. By End-user
11.5.3. By Country/Sub-region
12. Latin America Prosthetic Disc Nucleus Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
12.2.1. Minimally Invasive Spine Surgery
12.2.2. Open Spine Surgery
12.3. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
12.3.1. Hospitals
12.3.2. Ambulatory Surgery Centers
12.3.3. Others
12.4. Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
12.4.1. Brazil
12.4.2. Mexico
12.4.3. Rest of Latin America
12.5. Latin America Prosthetic Disc Nucleus Market Attractiveness Analysis
12.5.1. By Surgery Type
12.5.2. By End-user
12.5.3. By Country/Sub-region
13. Middle East & Africa Prosthetic Disc Nucleus Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
13.2.1. Minimally Invasive Spine Surgery
13.2.2. Open Spine Surgery
13.3. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
13.3.1. Hospitals
13.3.2. Ambulatory Surgery Centers
13.3.3. Others
13.4. Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
13.4.1. GCC Countries
13.4.2. South Africa
13.4.3. Rest of Middle East & Africa
13.5. Middle East & Africa Prosthetic Disc Nucleus Market Attractiveness Analysis
13.5.1. By Surgery Type
13.5.2. By End-user
13.5.3. By Country/Sub-region
14. Competitive Landscape
14.1. Market Player – Competition Matrix (By Tier and Size of companies)
14.2. Company Share Analysis
14.3. Company Profiles
14.3.1. Stryker Corporation
14.3.1.1Company Overview (HQ, Business Segments, Employee Strength)
14.3.1.2.Financial Overview
14.3.1.3.Product Portfolio
14.3.1.4.Strategic Overview
14.3.1.5.SWOT Analysis
14.3.2. Zimmer Biomet Holdings, Inc.
14.3.2.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.2.2.Financial Overview
14.3.2.3.Product Portfolio
14.3.2.4.Strategic Overview
14.3.2.5.SWOT Analysis
14.3.3. DePuy Synthes (Johnson & Johnson)
14.3.3.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.3.2.Financial Overview
14.3.3.3.Product Portfolio
14.3.3.4.Strategic Overview
14.3.3.5.SWOT Analysis
14.3.4. NuVasive, Inc.
14.3.4.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.4.2.Financial Overview
14.3.4.3.Product Portfolio
14.3.4.4.Strategic Overview
14.3.4.5.SWOT Analysis
14.3.5. Orthofix International N.V.
14.3.5.1.Company Overview (HQ, Business Segments, Employee Strength)
14.3.5.2.Financial Overview
14.3.5.3.Product Portfolio
14.3.5.4.Strategic Overview
14.3.5.5.SWOT Analysis
14.3.6. Replication Medical, Inc.
14.3.6.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.6.2.Financial Overview
14.3.6.3.Product Portfolio
14.3.6.4.Strategic Overview
14.3.6.5.SWOT Analysis
14.3.7. Spine Wave, Inc.
14.3.7.1. Company Overview (HQ, Business Segments, Employee Strength)
14.3.7.2.Financial Overview
14.3.7.3.Product Portfolio
14.3.7.4.Strategic Overview
14.3.7.5.SWOT Analysis
List of Tables
Table01: Incidence of Low Back Pain and Degenerative Spine Disease Worldwide, by World Bank Income Group (1/3)
Table 02: Incidence of Low Back Pain and Degenerative Spine Disease Worldwide, by World Bank Income Group (2/3)
Table 03: Incidence of Low Back Pain and Degenerative Spine Disease Worldwide, by World Bank Income Group (3/3)
Table 04: Incidence of Disc Degeneration and Spinal Stenosis Worldwide, by World Bank Income Group and WHO Region (1/3)
Table 05: Incidence of Disc Degeneration and Spinal Stenosis Worldwide, by World Bank Income Group and WHO Region (2/3)
Table 06: Incidence of Disc Degeneration and Spinal Stenosis Worldwide, by World Bank Income Group and WHO Region (3/3)
Table 07: Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 08: Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 09: Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Region, 2018–2030
Table 10: North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 11: North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 12: North America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country, 2018–2030
Table 13: Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 14: Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 15: Europe Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
Table 16: Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 17: Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 18: Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
Table 19: Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 20: Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 21: Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
Table 22: Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Surgery Type, 2018–2030
Table 23: Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by End-user, 2018–2030
Table 24: Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, by Country/Sub-region, 2018–2030
List of Figures
Figure 01: Global Prosthetic Disc Nucleus Market Value (US$ Mn) Forecast, 2018–2030
Figure 02: Global Prosthetic Disc Nucleus Market Value Share, by Surgery Type, 2019
Figure 03: Global Prosthetic Disc Nucleus Market Value Share, by End-user, 2019
Figure 04: Global Prosthetic Disc Nucleus Market Value Share, by Region, 2019
Figure 05: Global Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 06: Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020 and 2030
Figure 07: Global Prosthetic Disc Nucleus Market Revenue (US$ Mn), by Minimally Invasive Spine Surgery, 2018–2030
Figure 08: Global Prosthetic Disc Nucleus Market Revenue (US$ Mn), by Open Spine Surgery, 2018–2030
Figure 09: Global Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 10: Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020 and 2030
Figure 11: Global Prosthetic Disc Nucleus Market Revenue (US$ Mn), by Hospitals, 2018–2030
Figure 12: Global Prosthetic Disc Nucleus Market Revenue (US$ Mn), by Ambulatory Surgery Centers, 2018–2030
Figure 13: Global Prosthetic Disc Nucleus Market Revenue (US$ Mn), by Others, 2018–2030
Figure 14: Global Prosthetic Disc Nucleus Market Value Share Analysis, by Region, 2019 and 2030
Figure 15: Global Prosthetic Disc Nucleus Market Attractiveness Analysis, by Region, 2020 and 2030
Figure 16: North America Prosthetic Disc Nucleus Market Value (US$ Mn) and Y-o-Y Growth (%) Forecast, 2018–2030
Figure 17: North America Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 18: North America Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020–2030
Figure 19: North America Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 20: North America Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020–2030
Figure 21: North America Prosthetic Disc Nucleus Market Value Share Analysis, by Country, 2019 and 2030
Figure 22: North America Prosthetic Disc Nucleus Market Attractiveness Analysis, by Country, 2020–2030
Figure 23: Europe Prosthetic Disc Nucleus Market Value (US$ Mn) and Y-o-Y Growth (%) Forecast, 2018–2030
Figure 24: Europe Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 25: Europe Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020–2030
Figure 26: Europe Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 27: Europe Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020–2030
Figure 28: Europe Prosthetic Disc Nucleus Market Value Share Analysis, by Country/Sub-region, 2019 and 2030
Figure 29: Europe Prosthetic Disc Nucleus Market Attractiveness Analysis, by Country/Sub-region, 2020–2030
Figure 30: Asia Pacific Prosthetic Disc Nucleus Market Value (US$ Mn) and Y-o-Y Growth (%) Forecast, 2018–2030
Figure 31: Asia Pacific Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 32: Asia Pacific Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020–2030
Figure 33: Asia Pacific Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 34: Asia Pacific Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020–2030
Figure 35: Asia Pacific Prosthetic Disc Nucleus Market Value Share Analysis, by Country/Sub-region, 2019 and 2030
Figure 36: Asia Pacific Prosthetic Disc Nucleus Market Attractiveness Analysis, by Country/Sub-region, 2020–2030
Figure 37: Latin America Prosthetic Disc Nucleus Market Value (US$ Mn) and Y-o-Y Growth (%) Forecast, 2018–2030
Figure 38: Latin America Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 39: Latin America Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020–2030
Figure 40: Latin America Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 41: Latin America Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020–2030
Figure 42: Latin America Prosthetic Disc Nucleus Market Value Share Analysis, by Country/Sub-region, 2019 and 2030
Figure 43: Latin America Prosthetic Disc Nucleus Market Attractiveness Analysis, by Country/Sub-region, 2020–2030
Figure 44: Middle East & Africa Prosthetic Disc Nucleus Market Value (US$ Mn) and Y-o-Y Growth (%) Forecast, 2018–2030
Figure 45: Middle East & Africa Prosthetic Disc Nucleus Market Value Share Analysis, by Surgery Type, 2019 and 2030
Figure 46: Middle East & Africa Prosthetic Disc Nucleus Market Attractiveness Analysis, by Surgery Type, 2020–2030
Figure 47: Middle East & Africa Prosthetic Disc Nucleus Market Value Share Analysis, by End-user, 2019 and 2030
Figure 48: Middle East & Africa Prosthetic Disc Nucleus Market Attractiveness Analysis, by End-user, 2020–2030
Figure 49: Middle East & Africa Prosthetic Disc Nucleus Market Value Share Analysis, by Country/Sub-region, 2019 and 2030