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Contrast medium or diagnostic imaging agent is a substance that enhances the contrast of structures and fluids present inside the body in medical imaging. The widely used contrast mediums are generally based on gadolinium (Gd). Based on the chemical structure and chelating part, these gadolinium-based contrast mediums are categorized into linear and macrocyclic agents. The macromolecule with cyclic portion structure is referred as macrocyclic compound. Gadolinium-based macrocyclic compounds used as contrast medium are referred as macrocyclic agents. 

Gadolinium-based macrocyclic agents include gadobutrol and gadoteridol. There are two structurally different compounds available: open chain and cyclic chain. The open chain agents are also called linear agents. The gadolinium ion is captured into ligand cavity to produce macrocyclic agents. Owing to lesser degree of dissociation, macrocyclic agents are considered more stable than linear agents. Stability of macrocyclic agents depend on the degree of dissociation and how tightly the chelates are formed with the gadolinium ion. Macrocyclic agents have proven to be the most stable agents as these do not bind to serum proteins. The stable macrocyclic agents are recommended in pregnancy and lactating patients. Ideally, macrocyclic agents should have the following characteristics: selectivity for biochemical targets, good ratio of specific to nonspecific binding, better safety profile, and signal amplification capabilities. 

Increasing number of diagnostic procedures and growing medical infrastructure are anticipated to drive the global macrocyclic agents market. Macrocyclic agents available in the market include Gadovist, ProHance, and Clariscan. Increase in the global use of gadolinium-based contrast agents is expected to fuel the growth of the global macrocyclic agents market. However, high costs are likely to hamper the growth of the global macrocyclic agents market. 

The global macrocyclic agents market has been segmented based on route of administration, procedure, application, and region. In terms of route of administration, the market has been segmented into oral, rectal, urethral, and parenteral. Increasing use of injectables in various procedures such as X-ray, CT scan, MRI, and ultrasound is expected to drive the global macrocyclic agents market. Based on procedure, the global macrocyclic agents market has been classified into X-ray, CT scan, MRI, and ultrasound. High number of approvals for MRI contrast media in various markets is one of the key factors driving the MRI segment. 

Based on application, the global macrocyclic agents market has been divided into radiology, interventional cardiology, interventional radiology, and others. The radiology segment is estimated to hold the largest market share due to increasing number of diagnostic procedures. 

In terms of region, the global macrocyclic agents market has been segmented into five key regions: Asia Pacific, North America, Europe, Latin America, and Middle East & Africa. North America is projected to hold the largest share of the global macrocyclic agents market during the forecast period. This is attributed to highly-developed medical infrastructure and increasing number of diagnostic procedures. Europe is expected to be the second largest market for macrocyclic agents. Rapidly developing countries such as India and China are anticipated to fuel the growth of the macrocyclic agents market in Asia Pacific. 

Major players in the global macrocyclic agents market include GE Healthcare, Bayer AG, Bracco Imaging S.p.A., Daiichi Sankyo Company Limited, Eisai Co. Ltd., and Guerbet Group. Bayer AG and Bracco Imaging S.p.A. are expected to account for considerable share of the global macrocyclic agents market.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Macrocyclic Agents Market