Reports
The global intraoperative radiation therapy market size was valued at US$ 121.7 Mn in 2024 and is projected to reach US$ 266.9 Mn by 2035, expanding at a CAGR of 7.4% from 2025 to 2035. The market growth is driven by rising global cancer incidence, growing demand for precise and effective cancer treatments, and paradigm shift towards minimally invasive and single‑session treatment approaches.

Adoption of intraoperative radiation therapy is driven by growing demand for single-session treatments, short hospitalization, and quick recovery, which is in congruence with value-based care models. Enhanced workflow efficiency and reduced procedure times decrease the expense of operations while enhancing patient outcome and satisfaction, causing hospitals to adopt IORT into surgical oncology treatment protocols and multidisciplinary treatment plans.
Favorable reimbursement frameworks and recognition of IORT’s cost-effectiveness enhance institutional adoption, particularly in healthcare systems where bundled payments incentivize procedural efficiency. Miniaturization of technologies to portable devices broadens application beyond tertiary facilities. Parallel investment in training personnel, multidisciplinary planning, and capital equipment acquisition also favors integration of IORT into national surgical oncology programs.
Current trends in the intraoperative radiation therapy market are focused on interaction of real-time imaging and dosimetry to achieve higher precision levels, and development of hybrid operating rooms facilitating multidisciplinary workflows. Manufacturers are advocating for community hospitals to acquire portable, battery-operated IORT units to broaden access. Additionally, the increasing amount of clinical evidence, digital treatment planning tools, and AI-assisted dose optimization, is driving protocol standardization and wider clinical acceptance.
Intraoperative radiation therapy represents a sophisticated cancer treatment process where the localized dose of radiation is administered to the tumor site during the operation. Oncologists can accurately target the cancerous tissues and avoid subjecting surrounding healthy organs and tissues to more radiation than necessary with this process.
The therapy is generally administered following tumor resection through surgery, in an effort to ensure that any remaining microscopic cancer cells are killed prior to surgical site closure. Localized delivery optimizes effectiveness of these treatment and minimizes repeated postoperative courses of radiotherapy, significantly lowering overall treatment time for patients.
IORT is generally associated with breast cancer, colon cancer, rectal cancer, pancreatic cancer, and gynaecological cancers, with that being a common feature among the diseases where accuracy and keeping the normal tissue intact are of utmost importance. When radiation is given intraoperatively, the practitioners can see and change the target area straight off, thus resulting in better dose precision and less side effects in comparison with the standard external beam radiation therapy.
Innovations in technology such as portable linear accelerators and real-time imaging devices have facilitated the widespread use of IORT in contemporary operating rooms. The method is an remarkable example of personalization of cancer care through the integration of radiation oncology and surgery in one single session, thereby giving patients the benefits of a rapid recovery, lesser chances of complications, and better local tumor control results.
| Attribute | Detail |
|---|---|
| Intraoperative Radiation Therapy Market Drivers |
|
The intraoperative radiation therapy (IORT) market is experiencing significant growth due to the rising number of cancer cases globally. This, in turn, requires the emergence of high-tech, precise, and affordable methods of treatment. With cancer continuing to pose a significant challenge for healthcare systems worldwide, there is a growing trend toward the use of treatments that combine the precision of surgery with local radiation to achieve better results.
With more patients requiring multimodal treatment modalities, IORT offers an acceptable solution through facilitating immediate application of radiation during surgery. This minimizes cancer cell recurrence and regrowth risks, enhancing rates of treatment success. The integration of IORT with oncologic surgery offers oncologists with an effective tool to cure complicated and recurrent tumors better.
The technique also addresses an increased need for quick cancer treatment. By minimizing the number of radiotherapy sessions following operation, IORT optimizes hospital space and enhances patient convenience, a significant consideration as cancer treatment centers worldwide contend with increasing patient volumes.
Moreover, the growing prevalence of cancer is compelling healthcare organizations to invest in highly advanced IORT devices. Hospitals and cancer treatment centers are implementing such devices to enhance the accuracy of surgery, and quality of patient care. Therefore, the growing prevalence of cancer worldwide remains a primary growth factor for the intraoperative radiation therapy industry.
Intraoperative radiation therapy (IORT) market is being fueled by the development of targeted therapies since these complement its precision medicine-based modality of treatment. With oncology increasingly moving towards personalized treatment, IORT is in concord with targeted therapies as these are both - focused on maximizing tumor control and reducing toxicity to normal tissues within proximity. This convergence is raising overall therapeutic effectiveness.
Targeted therapies target and destroy specific molecular targets on cancer cells, whereas IORT gives a focused dose of radiation to the tumor bed at the time of surgery. These modalities together give a double approach molecular and localized physical therapy that intensifies results in diffuse or refractory cancers. Combined modality underpins the evolving paradigm of precision oncology.
Increased efficacy of targeted therapies has increased awareness of individualized and site-specific treatment modalities. This has prompted healthcare facilities to implement modalities such as IORT that can be modified based on the needs of individual patients, enhancing local tumor control and recovery after treatment. The overlap of these modalities is an indicator of the movement toward multidisciplinary treatment of cancer.
Further, research studies in targeted drug delivery systems and radiobiology are creating a path for the advancement of IORT devices and techniques. Similarly, the synergistic effects of IORT and targeted therapies are likely to trigger studies on their application through interdisciplinary collaborations, clinical trials, and product development that will eventually further clinical applications and market growth for IORT.

Electron Intraoperative Radiotherapy (IORT) is dominant segment for intraoperative radiation therapy industry. This is due to the high precision delivery of radiation, the ability to easily modify the dose distribution, and the protection of the healthy tissue in the surrounding area. In essence, this allows physicians to deliver radiation accurately following the removal of the tumor which leads to less local failure, and improved patient outcomes for multiple cancer types, but especially breast and colorectal cancer.
In addition, electron IORT units can offer a broader range of options and shorter treatment time than the other sources of radiation. Since they can be easily incorporated into existing surgical workflows, and they are compatible with portable linear accelerators, hospitals are more likely to have them. These benefits explain their strong clinical acceptance and market share.

| Attribute | Detail |
|---|---|
| Leading Region |
|
As per the latest intraoperative radiation therapy market analysis, North America dominated in 2024, capturing a market share of 43.5%. This is essentially attributed to the region's exceptionally developed healthcare framework, rapid uptake of technologically advanced cancer treatment methods, and the presence of a robust clinical research ecosystem. In essence, North America's well-equipped and structured hospitals and cancer centers are the major contributors in the active incorporation of IORT in multidisciplinary oncology programs for enhancing surgical precision and improving patient outcomes.
Additionally, the ongoing clinical trials, government initiatives that respond to the needs of cancer care sector, and uninterrupted technological innovations by manufacturers in the area are also the important factors contributing to North America's sustaining leadership position in the global intraoperative radiation therapy market.
The key market strategies adopted by companies operating in the intraoperative radiation therapy industry include product innovation with portable and compact IORT units, strategic collaborations with research institutions and hospitals, and expansion through clinical trial sponsorships. Further, enterprises are investing in service-based models, training programs, and regulatory approvals for consolidating their position in the market, increasing the accessibility, and speedingup the worldwide adoption of intraoperative radiation therapy solutions.
ZEISS Group, Elekta, Varian (Siemens Healthineers), Sensus Healthcare, Inc., S.I.T. Sordina IORT Technologies S.p.A., Eckert & Ziegler, Becton, Dickinson and Company, Synektik, iCAD, Inc., Accuray Incorporated, PTW Freiburg GmbH, SeeDOS Ltd, Theragenics Corporation, BEBIG Medical. and CIVCO Medical Solutions are some of the leading players operating in the global intraoperative radiation therapy market.
Each of these players has been profiled in the intraoperative radiation therapy market research report based on parameters such as company overview, financial overview, business strategies, product portfolio, business segments, and recent developments.
| Attribute | Detail |
|---|---|
| Size in 2024 | US$ 121.7 Mn |
| Forecast Value in 2035 | US$ 266.9 Mn |
| CAGR | 7.4% |
| Forecast Period | 2025-2035 |
| Historical Data Available for | 2020-2023 |
| Quantitative Units | US$ Mn |
| Intraoperative Radiation Therapy Market Analysis | It includes segment analysis as well as regional level analysis. Moreover, qualitative analysis includes drivers, restraints, opportunities, key trends, value chain analysis, and key trend analysis. |
| Competition Landscape |
|
| Format | Electronic (PDF) + Excel |
| Segmentation | Technology
|
| Regions Covered |
|
| Countries Covered |
|
| Companies Profiled |
|
| Customization Scope | Available upon request |
| Pricing | Available upon request |
The global intraoperative radiation therapy market was valued at US$ 121.7 Mn in 2024
The global intraoperative radiation therapy industry is projected to reach more than US$ 266.9 Mn by the end of 2035
The rising global cancer incidence, demand for more precise and effective cancer treatments, technological advancements, such as AI and machine learning, and the advantages of IORT over traditional radiotherapy are some of the factors driving the expansion of intraoperative radiation therapy market.
The CAGR is anticipated to be 7.4% from 2025 to 2035
ZEISS Group, Elekta, Varian (Siemens Healthineers), Sensus Healthcare, Inc., S.I.T. Sordina IORT Technologies S.p.A., Eckert & Ziegler, Becton, Dickinson and Company, Synektik, iCAD, Inc., Accuray Incorporated, PTW Freiburg GmbH, SeeDOS Ltd, Theragenics Corporation, BEBIG Medical, and CIVCO Medical Solutions
Table 01: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 02: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 03: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 04: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 05: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Table 06: Global Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Region, 2020 to 2035
Table 07: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, by Country, 2020-2035
Table 08: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 09: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 10: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 11: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 12: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Table 13: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, by Country/Sub-region, 2020-2035
Table 14: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 15: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 16: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 17: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 18: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Table 19: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, by Country/Sub-region, 2020-2035
Table 20: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 21: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 22: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 23: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 24: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Table 25: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, by Country/Sub-region, 2020-2035
Table 26: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 27: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 28: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 29: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 30: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Table 31: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, by Country/Sub-region, 2020-2035
Table 32: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Technology, 2020 to 2035
Table 33: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products and Services, 2020 to 2035
Table 34: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Products, 2020 to 2035
Table 35: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By Indication, 2020 to 2035
Table 36: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, By End-users, 2020 to 2035
Figure 01: Global Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 02: Global Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 03: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Electron Intraoperative radiotherapy (IORT), 2020 to 2035
Figure 04: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by High-Dose-Rate (HDR) Brachytherapy, 2020 to 2035
Figure 05: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Others, 2020 to 2035
Figure 06: Global Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 07: Global Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 08: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Products, 2020 to 2035
Figure 09: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Software, 2020 to 2035
Figure 10: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Services, 2020 to 2035
Figure 11: Global Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 12: Global Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 13: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Head & Neck Cancer, 2020 to 2035
Figure 14: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Gastrointestinal Cancer, 2020 to 2035
Figure 15: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Colorectal Cancer, 2020 to 2035
Figure 16: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Lung Cancer, 2020 to 2035
Figure 17: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Endometrial & Cervical Cancer, 2020 to 2035
Figure 18: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Breast Cancer, 2020 to 2035
Figure 19: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Penile & Prostate Cancer, 2020 to 2035
Figure 20: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Others, 2020 to 2035
Figure 21: Global Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 22: Global Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035
Figure 23: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Hospitals, 2020 to 2035
Figure 24: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Oncology Clinics, 2020 to 2035
Figure 25: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Ambulatory Surgical Centers, 2020 to 2035
Figure 26: Global Intraoperative Radiation Therapy Market Revenue (US$ Mn), by Academic and Research Institutes, 2020 to 2035
Figure 27: Global Intraoperative Radiation Therapy Market Value Share Analysis, By Region, 2024 and 2035
Figure 28: Global Intraoperative Radiation Therapy Market Attractiveness Analysis, By Region, 2025 to 2035
Figure 29: North America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, 2020 to 2035
Figure 30: North America Intraoperative Radiation Therapy Market Value Share Analysis, by Country, 2024 and 2035
Figure 31: North America Intraoperative Radiation Therapy Market Attractiveness Analysis, by Country, 2025 to 2035
Figure 32: North America Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 33: North America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 34: North America Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 35: North America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 36: North America Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 37: North America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 38: North America Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 39: North America Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035
Figure 40: Europe Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, 2020 to 2035
Figure 41: Europe Intraoperative Radiation Therapy Market Value Share Analysis, by Country/Sub-region, 2024 and 2035
Figure 42: Europe Intraoperative Radiation Therapy Market Attractiveness Analysis, by Country/Sub-region, 2025 to 2035
Figure 43: Europe Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 44: Europe Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 45: Europe Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 46: Europe Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 47: Europe Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 48: Europe Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 49: Europe Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 50: Europe Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035
Figure 51: Asia Pacific Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, 2020 to 2035
Figure 52: Asia Pacific Intraoperative Radiation Therapy Market Value Share Analysis, by Country/Sub-region, 2024 and 2035
Figure 53: Asia Pacific Intraoperative Radiation Therapy Market Attractiveness Analysis, by Country/Sub-region, 2025 to 2035
Figure 54: Asia Pacific Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 55: Asia Pacific Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 56: Asia Pacific Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 57: Asia Pacific Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 58: Asia Pacific Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 59: Asia Pacific Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 60: Asia Pacific Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 61: Asia Pacific Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035
Figure 62: Latin America Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, 2020 to 2035
Figure 63: Latin America Intraoperative Radiation Therapy Market Value Share Analysis, by Country/Sub-region, 2024 and 2035
Figure 64: Latin America Intraoperative Radiation Therapy Market Attractiveness Analysis, by Country/Sub-region, 2025 to 2035
Figure 65: Latin America Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 66: Latin America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 67: Latin America Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 68: Latin America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 69: Latin America Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 70: Latin America Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 71: Latin America Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 72: Latin America Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035
Figure 73: Middle East & Africa Intraoperative Radiation Therapy Market Value (US$ Mn) Forecast, 2020 to 2035
Figure 74: Middle East & Africa Intraoperative Radiation Therapy Market Value Share Analysis, by Country/Sub-region, 2024 and 2035
Figure 75: Middle East & Africa Intraoperative Radiation Therapy Market Attractiveness Analysis, by Country/Sub-region, 2025 to 2035
Figure 76: Middle East & Africa Intraoperative Radiation Therapy Market Value Share Analysis, By Technology, 2024 and 2035
Figure 77: Middle East & Africa Intraoperative Radiation Therapy Market Attractiveness Analysis, By Technology, 2025 to 2035
Figure 78: Middle East & Africa Intraoperative Radiation Therapy Market Value Share Analysis, By Products and Services, 2024 and 2035
Figure 79: Middle East & Africa Intraoperative Radiation Therapy Market Attractiveness Analysis, By Products and Services, 2025 to 2035
Figure 80: Middle East & Africa Intraoperative Radiation Therapy Market Value Share Analysis, By Indication, 2024 and 2035
Figure 81: Middle East & Africa Intraoperative Radiation Therapy Market Attractiveness Analysis, By Indication, 2025 to 2035
Figure 82: Middle East & Africa Intraoperative Radiation Therapy Market Value Share Analysis, By End-users, 2024 and 2035
Figure 83: Middle East & Africa Intraoperative Radiation Therapy Market Attractiveness Analysis, By End-users, 2025 to 2035