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Market Players Focus on Improving Existing Chronic Idiopathic Constipation Therapies

Chronic idiopathic constipation is a highly prevalent functional bowel disorder that affects millions of individuals worldwide. Some of the major factors that contribute to the burgeoning number of patients suffering from chronic idiopathic constipation include sedentary lifestyle, increasing usage of anti-inflammatory agents, and drastic decline in the intake of dietary fibers. Over the past few years, considerable efforts have been made to improve the management of chronic idiopathic constipation. In the current scenario, empiric therapy has garnered considerable attention from the stakeholders operating in the current chronic idiopathic constipation treatment market – a trend that is expected to continue during the forecast period.

Researchers involved in the current chronic idiopathic constipation treatment market landscape are also increasingly focusing on the development of customized treatment plans that offer multi-symptom relief. Efforts are being made to improve the efficacy of the current therapeutic agents due to which, a steady growth of the global chronic idiopathic constipation treatment market is anticipated in the upcoming years. A number of players involved in the current market for chronic idiopathic constipation treatment are focusing on gaining approval from the FDA for the newly developed drugs and treatments.

At the back of these factors, along with the augmenting demand for chronic idiopathic constipation treatment, the global chronic idiopathic constipation treatment market is expected to surpass the US$ 15.9 Bn mark by the end of 2030.

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Consistent Progress in Management of Chronic Idiopathic Constipation to Bolster Market Growth

In the initial stages, chronic idiopathic constipation treatment primarily included a blend of medication review, lifestyle modifications, and patient education. While prescription treatments are expected to witness considerable adoption worldwide, a number of non-prescription chronic idiopathic constipation treatments, including fiber supplementation, has garnered popularity. Moreover, research activities suggest that soluble fibers such as psyllium offer relief to patients suffering from chronic idiopathic constipation in comparison with insoluble fibers including bran. The increasing usage of soluble fibers has led to a noteworthy improvement in global symptoms and stool consistency due to which, the chronic idiopathic constipation treatment market is largely leaning toward the utilization of soluble fibers in the empiric fiber therapy. The rising usage of osmotic laxatives, stimulant laxative, and bulking laxatives is expected to contribute to the growth of the global chronic idiopathic constipation treatment market as the demand for non-prescription treatments continues to move in the upward trajectory.

While non-prescription treatments are gradually gaining worldwide adoption, the demand for prescription treatments is on the rise. However, players operating in the current chronic idiopathic constipation treatment market landscape are increasingly focusing on catering to the unmet needs with existing chronic idiopathic constipation treatment alternatives.

Unpredictability, poor symptom relief, bloating, and inability to enhance the quality of life of current treatments have compelled companies in the current market for chronic idiopathic constipation treatment to introduce better prescription agents and mechanisms. Some of the recently developed prescription agents that are gaining fast-paced adoption include prosecretory agents and a host of FDA approved products such as linaclotide.

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FDA Approval of New Drugs to Aid Market Growth

In the current scenario, manufacturers operating in the chronic idiopathic constipation treatment market are increasingly seeking the approval of the FDA for their newly developed drugs. Gaining the approval of the FDA is expected to remain one of the core areas of focus for the chronic idiopathic constipation drug manufacturers over the course of the forecast period. A number of drugs has received the green signal from the FDA in recent years.

In February 2020, the U.S. FDA approved an osmotic laxative developed by the Braintree Laboratories to treat chronic idiopathic constipation among adults. While attaining the FDA approval is expected to remain a top priority, market players are likely to increase the R&D spending on the development of new therapeutics and products.

Moderate Impact of COVID-19 Pandemic on Global Market

The onset of the COVID-19 pandemic is expected to have a moderate impact on the global chronic idiopathic constipation treatment market in 2020. The first quarter of 2020 witnessed steady ascension in the demand for chronic idiopathic constipation treatment worldwide. However, outbreak of the COVID-19 pandemic toward the end of the first quarter and stringent lockdown measures implemented by governments in the second and the third quarter of 2020 are expected to negatively affect the adoption of chronic idiopathic constipation treatment. However, the demand is set to witness considerable growth toward the end of 2020, as governments around the world continue to lift the lockdown measures in a phased manner.

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Analysts’ Viewpoint

The global chronic idiopathic constipation treatment market is expected to grow at a healthy CAGR of ~7% during the forecast period. The market growth can be primarily attributed to factors such as increasing prevalence of chronic idiopathic constipation among adults worldwide, high demand for improved chronic idiopathic constipation treatment and therapies to address unmet needs of existing treatments, and research and development activities. Market players should focus on the development of new prescription as well as non-prescription chronic idiopathic constipation treatments and continue to invest in R&D activities.

Chronic Idiopathic Constipation Treatment Market: Overview

  • According to Transparency Market Research’s latest report on the global chronic idiopathic constipation treatment market for the historical period 2018–2019 and forecast period 2020–20230, promising pipeline is anticipated to drive the global m chronic idiopathic constipation treatment market
  • Constipation is a highly common chronic gastrointestinal disorder. Chronic idiopathic constipation (CIC) is a health condition in which a patient experiences chronic symptoms of constipation. Changing dietary habits, i.e., reduction in fluid and fiber intake in diet, changes in water balance, and changes in contractility of the colon cause chronic idiopathic constipation.

Increase in Demand for CIC Treatment Products to Drive Chronic Idiopathic Constipation Treatment Market

  • Steady rise in prevalence of constipation across the global population is leading to high demand for newer therapeutics. This, in turn, is estimated to drive the market. Healthcare providers and patients both report unmet needs with current chronic idiopathic constipation treatment options.
  • Around 50% of patients with chronic idiopathic constipation report dissatisfaction with non-prescription laxatives due to unpredictability, bloating, poor symptom relief, or inability to improve quality of life. Alternative agents with novel mechanisms of action are being developed for the last 10 years in order to address these concerns.
  • Likewise, several of the available specialty drugs are intended for use in adolescents and adult patients. Surge in incidence of constipation among children is likely to present significant opportunities for key players and new entrants to develop and launch specialty constipation drugs for pediatric use.

Rise in Healthcare Spending and Improvements in Healthcare Infrastructure Propel Chronic Idiopathic Constipation Treatment Market

  • Increase in the number of patients with chronic idiopathic constipation boosts adoption of newer products. Patients are more aware and proactive about their health, and are willing to seek effective treatment. Hence, rise in healthcare spending on constipation is likely to boost the market.
  • An article published in the American Journal of Managed Care in 2007 stated that people in the U.S. spent more than US$ 800 million on laxatives. Chronic idiopathic constipation has a significant impact on the healthcare system, and it accounted for 3.92% of all ambulatory care visits in the U.S. in 2014.

High Cost to Hamper Chronic Idiopathic Constipation Treatment Market

  • Chronic idiopathic constipation continues to be associated with significant costs. It is like numerous other common conditions that contribute to greater morbidity and healthcare costs.
  • An article published in the American Journal of Managed Care stated that around 81% of cost of chronic idiopathic constipation treatment is associated with the use of medical services, including visits to prescribers and outpatient services. It is reported that pharmacy costs for chronic constipation patients with abdominal symptoms is 1.6 times higher than patients who did not have abdominal symptoms.
  • Cost of treatment is an important concern regarding the selection of treatment. Hence, higher cost associated with treatment hampers the market. For instance, the annual cost of treatment of chronic idiopathic constipation ranges from US$ 1,912 to US$ 7,522 per patient. In the U.S., direct medical cost of medical constipation is estimated at US$ 230 million per year.

Chronic Idiopathic Constipation Treatment Market: Competition Landscape

  • This report profiles major players operating in the global chronic idiopathic constipation treatment market based on various attributes and recent developments
  • The global chronic idiopathic constipation treatment market is highly fragmented with the presence of numerous global as well as regional players
  • Leading players operating in the global chronic idiopathic constipation treatment market include
    • Bayer AG
    • Allergan
    • Bausch Health
    • Sanofi
    • Takeda Pharmaceutical Company
    • SEBELA PHARMACEUTICALS
    • Ironwood Pharmaceuticals, Inc.
    • Albireo Pharma, Inc.
    • Sucampo Pharmaceuticals, Inc. (Mallinckrodt)
    • Janssen Pharmaceuticals, Inc. (Johnson & Johnson)

Chronic Idiopathic Constipation Treatment Market: Key Developments

  • Key players in the global chronic idiopathic constipation treatment market are engaged in regulatory approvals, technologically advanced products, launch of new products, and acquisition & collaborative agreements with other companies. These strategies are aimed at addressing unmet needs in the chronic idiopathic constipation treatment market, strengthening the product portfolio, and investing in research & development.
  • A few expansion strategies adopted by players operating in the global chronic idiopathic constipation treatment market are:
  • In April 2020, Ironwood Pharmaceuticals, Inc. announced that the USPTO (United States Patent and Trademark) issued Notices of Allowance for patent applications covering the formulation of the 72 mcg dose of LINZESS
  • In March 2020, SEBELA PHARMACEUTICALS received approval from the U.S. Food and Drug Administration for Pizensy (lactitol). This approval represents a step forward in the treatment options for CIC.
  •  In September 2019, Ironwood Pharmaceuticals, Inc. entered into an amended collaboration agreement with AstraZeneca for the development and commercialization of LINZESS, in China
  • In February 2018, Mallinckrodt acquired Sucampo. Sucampo's primary commercialized product was Amitiza, a leading global product in the branded constipation market
  • The report on the global chronic idiopathic constipation treatment market discussed individual strategies, followed by company profiles of manufacturers of chronic idiopathic constipation treatment products. The competition landscape section has been included in the report to provide readers with a dashboard view and a company market share analysis of key players operating in the global chronic idiopathic constipation treatment market.

Chronic Idiopathic Constipation Treatment Market – Scope of the Report

TMR’s report on the global chronic idiopathic constipation treatment market studies past as well as current growth trends and opportunities to gain valuable insights of these indicators of the market during the forecast period from 2020 to 2030. The report provides revenue of the global chronic idiopathic constipation treatment market for the period 2018–2030, considering 2019 as the base year and 2030 as the forecast year. The report also provides the compound annual growth rate (CAGR) for the global chronic idiopathic constipation treatment market during the forecast period.

The report has been prepared after primary and secondary researches. Primary research involved bulk of research efforts, wherein analysts carried out interviews with industry leaders and opinion makers. Extensive secondary research involved referring to key players’ product literature, annual reports, press releases, and relevant documents to understand the global chronic idiopathic constipation treatment market.

Secondary research also included Internet sources, statistical data from government agencies, websites, company presentations, sales data, and trade associations. Analysts employed a combination of top-down and bottom-up approaches to study various phenomenon in the global chronic idiopathic constipation treatment market.

The report includes an elaborate executive summary, along with a snapshot of the growth behavior of various segments included in the scope of the study. Furthermore, the report sheds light on the changing competitive dynamics in the global chronic idiopathic constipation treatment market. These indices serve as valuable tools for existing market players as well as for entities interested in entering the global chronic idiopathic constipation treatment market.

The report delves into the competition landscape of the global chronic idiopathic constipation treatment market. Key players operating in the global chronic idiopathic constipation treatment market have been identified, and each one of these has been profiled for distinguishing business attributes. Company overview, financial standings, recent developments, and SWOT are some of the attributes of players in the global chronic idiopathic constipation treatment market that have been profiled in this report.

Key Questions Answered in Chronic Idiopathic Constipation Treatment Market Report

  • What is the scope of growth for product companies in the global chronic idiopathic constipation treatment market?
  • What will be the Y-o-Y growth of the global chronic idiopathic constipation treatment market between 2020 and 2030?
  • What is the influence of changing trends in technologies on the global chronic idiopathic constipation treatment market?
  • Will North America continue to be the most profitable market for chronic idiopathic constipation treatment?
  • Which factors are anticipated to hamper the global chronic idiopathic constipation treatment market during the forecast period?
  • Which are the leading companies in the global chronic idiopathic constipation treatment market?

Research Methodology

A unique methodology has been utilized by TMR to conduct comprehensive research on the growth of the global chronic idiopathic constipation treatment market and arrive at conclusions on its growth prospects. This research methodology is a combination of primary and secondary research, which helps analysts warrant the accuracy and reliability of the drawn conclusions.

Secondary research sources referred to by analysts during the production of the global chronic idiopathic constipation treatment market report include statistics from company annual reports, SEC filings, company websites, investor presentations, regulatory databases, government publications, and industry white papers. Analysts have also interviewed senior managers, product portfolio managers, CEOs, VPs, and market intelligence managers, who contributed to the production of TMR’s study on the chronic idiopathic constipation treatment market as primary methods.

These primary research respondents have provided exclusive information during interviews, which serves as a validation from the chronic idiopathic constipation treatment market leaders. Access to an extensive internal repository and external proprietary databases enabled this report to address specific details and questions about the global chronic idiopathic constipation treatment market with accuracy. The study also uses the top-down approach to assess the revenues of each segment and the bottom-up approach to counter-validate them. This has helped in reaching TMR’s estimates on future prospects of the global chronic idiopathic constipation treatment more reliably and accurately.

Chronic Idiopathic Constipation Treatment Market – Segmentation

Drug Class

  • Serotonin-4 (5-Ht4) Receptor Agonist
    • Prucalopride
    • Others
  • Guanylate Cyclase-C Agonist
    • Plecanatide
    • Linaclotide     
  • Laxatives
    • Sodium Picosulphate
    • Polycarbophil
    • Others
  • Stimulants
    • Bisacodyl
    • Senokot
    • Others
  • Others

Route of Administration

  • Oral
  • Rectal

Distribution Channel

  • Hospital Pharmacies   
  • Retail Pharmacies       
  • Online Pharmacies     

Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

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Chronic Idiopathic Constipation Treatment Market

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