Brucellosis is an extremely transmissible zoonotic infection. Bacterial genus Brucella is responsible for the infection. Brucella are transferred from animals to humans through consumption of infected foodstuff, undercooked meat, or unpasteurized milk from diseased animals; direct contact with an infected animal or their discharges; or inhalation of aerosols. According to the WHO, zoonotic diseases and infections are naturally transferred between vertebrate animals and humans. A zoonotic agent may be a fungus, virus, bacterium, or any other infectious disease agent. Brucellosis is an old disease that has been known by several names such as undulant fever, gastric remittent fever, Malta fever, and Mediterranean fever. Humans are unintended hosts, but brucellosis continues to be a highly significant community health concern at the global level and the most common zoonotic infection as well.
Brucella bacteria are minor aerobic intracellular coccobacilli, which are localized in reproductive organs of the host animal, causing infertility and abortions. They are sheltered in large numbers in the animal’s placental fluid, milk, urine, and other fluids. To date, eight species of Brucella bacteria have been identified, termed primarily after the source animal or symptoms of infection. Out of these, four species possess medium to serious human pathogenicity. These are Brucella canis (transferred from dogs; moderate pathogenicity), Brucella abortus (transferred from cattle; moderate pathogenicity), Brucella suis (transferred from pigs; high pathogenicity), and Brucella melitensis (transferred from sheep; maximum pathogenicity).
Even though brucellosis infection occurs in pets, it is also observed in wild animals that are found in herds (for example, wild boar in Germany and elk or bison in North America). Humans have only a partial threat of infection from wild animals, mostly due to lack of contact and rare use of meat and milk of these wild animals. There have been concerns about the spread of infection to farming livestock due to contact of wild animals with pets; however, the supporting proof in this regard is limited. The worldwide burden of human brucellosis remains very high. More than 500,000 infections are caused by animals across the world every year. The yearly figure of reported cases in the U.S. (currently, around 100) has dropped considerably, owing to milk pasteurization and aggressive animal vaccination campaigns. Most of the cases in the U.S. are caused by the intake of unpasteurized dairy foods imported from Mexico. Nearly 60% of human brucellosis cases in the country are currently found in California and Texas.
Brucella abortus vaccines play an essential role in bovine brucellosis eradication or control programs. They have been effectively used worldwide for several years. RB51 and Strain 19 are accepted B. abortus vaccines strains, most frequently used to protect cattle from abortion and infection. B. abortus vaccines such as Strain 19 are live attenuated vaccines. Strain 19 was the first vaccine to be used widely for bovine brucellosis treatment or control. Strain 19 vaccine has been used in the U.S. since 1941 and it is still in use in various countries worldwide. B. abortus strain RB51, a Rifampicin-resistant strain, lacks of appearance of LPS (lipopolysaccharide) O-side chains (OPS). In 1982, Prof. Gerhardt Schurig et al. developed the RB51 vaccine strain by isolating it from infectious smooth B. abortus biovar 1 strain 2308. There are several factors boosting the market for brucellosis vaccines including technological innovations, increasing awareness about animal health, and rising funding by government organizations and associations. Also, the increased demand for fish, eggs, milk, and animal protein and risen expenditure on health care of companion animals are driving the brucellosis vaccines market.
The global brucellosis vaccines market can be segmented based on type of product, application, end-user, and geography. Based on type of product, the brucellosis vaccines market has been classified as DNA vaccines, subunit vaccines, vector vaccines, B. Abortus recombinant mutants, and others. Based on application, the market has been categorized into cattle, sheep, pigs, and others. Based on end-user, the market has been classified into veterinary hospitals, veterinary clinics, and animal care centers. Based on geography, the global brucellosis vaccines market has been divided into North America, Europe, Asia Pacific, and Rest of World.
Major players operating in the global brucellosis vaccines market are Merck Animal Health, Boehringer Ingelheim Vetmedica, Ceva, Bayer AG, Biogenesis-Bago, Heska Corporation, Indian Immunologicals Ltd., Lohmann Animal Health, and Merial Ltd.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
2. Insights and Tools
The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.
3. Actionable Results
The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.