3D printing is a process used to produce three-dimensional objects. The object is produced using computer-aided software, by adding successive layers of materials on the product to generate 3D shape (additive manufacturing). 3D bioprinting works on the same principle as traditional 3D printing, except the procedure is done using live cells, tissues, and organs, where the complexities of tissues and cells, such as cell type, functionalities, growth, and differentiation patterns are addressed. The process of 3D bioprinting involves dispensing cells onto a biocompatible scaffold using a successive layer-by-layer approach to generate tissue-like three-dimensional structures. The bioprinting process can be customized to develop tissues in various formats and designs, from micro-scale tissues to larger structures. The micro-scale tissue structure is useful for cell study and culture plates preemption, whereas large scale structure is useful in placement on bioreactors for biochemical reactions.
The global 3D bioprinting market is anticipated to witness strong growth during the forecast period. Rapidly increasing technological advancements in pharmaceutical and biotechnology sectors, rise in demand for 3D printers in various studies such as drug discovery and development, and surge in demand for new and advanced drug screening tests such as toxicity screening are the major factors anticipated to drive the global 3D bioprinting market during the forecast period. Advantages of 3D bioprinters and growing clinical and research applications in the pharmaceutical industry fuel the growth of the global market. High cost of equipment and lack of penetration and adoption of the 3D bioprinting technique in emerging countries are the factors restraining the global 3D bioprinting market. However, recent advances in 3D bioprinting in the field of biotechnology and establishment of the technique in the fields of tissue transplantation, multilayer skin transplant, vascular grafts, bone, and other important tissues and organs have created new opportunities in the global market.
The global 3D bioprinting market can be segmented based on technique, application, end-user, and region. In terms of technique, the market can be categorized into electron beam melting, laser beam melting, photo polymerization (stereo lithography, digital light processing, and two-photon polymerization), and droplet disposition (inkjet printing, fused disposition methods, and multi-phase jet solidification) techniques. Based on application, the global 3D bioprinting market can be classified into clinical applications (transplantation of tissues, bone, vascular grafts, and others) and research applications (regenerative medicine, personalized healthcare, and others). The clinical applications segment accounted for the largest share of the global market in 2016. However, increase in number of research institutes and contract research organizations using 3D bioprinting techniques for research in pharmaceutical and biotechnology applications are the major factors expected to propel the growth of the market from 2017 to 2025. In terms of end-user, the global market can be divided into pharmaceutical & biotechnology companies, academic & research institutes, and contract research organizations.
In terms of region, the global 3D bioprinting market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to dominate the global market from 2017 to 2025, owing to increase in per capita R&D spending in the region along with rise in demand for new and advanced products and techniques. Europe accounted for the second largest share of the global market in 2016 due to increase in number of pharmaceutical and biotechnology companies investing in research applications of 3D bioprinting.
Major companies operating in the global 3D bioprinting market are Nano3D Biosciences, Inc., Organovo Holdings, Inc., Aspect Biosystems Ltd., GeSiM, Regenovo Biotechnology Co., Ltd., nScrypt, Inc., Stratasys Ltd., EnvisionTEC GmbH, regenHU, 3D Systems, Inc., Rainbow Biosciences, and TeVido BioDevices.
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