Short Bowel Syndrome Market: Overview
Short bowel syndrome (SBS) is the malabsorption of nutrients caused by removal of small intestine and in rare cases, the dysfunction of particular segments of the bowel. Nutrients are absorbed by the small intestine with the help of villi that are connected to blood capillaries. The condition is extremely rare and affected people exhibit symptoms such as abdominal pain, diarrhea, dehydration, weight loss, fatigue, malnutrition and weakness. Deficiencies of major nutrients such as vitamins and minerals can cause a host of other illnesses and disorders such as swelling, easy, bruising, difficulty in blood clotting, reduced immunological response, anemia, hyperkeratosis, bone and joint pain due to osteoporosis. The condition is also known as Small Intestine Insufficiency.
Surgical removal of small intestine can occur mainly under three conditions; necrotizing enterocolitis that is the death of intestinal wall due to reduced blood supply, malformation of intestine and Crohn’s Disease which is a condition that causes inflammation of the bowel wall and attacks all parts of the digestive tract, from mouth to anus, for unknown reasons. Crohn’s Disease is a fairly uncommon disease that affects approximately 4.5 million people across the world. According to data from CDC, NIH and other organizations, incidence of Crohn’s Disease is estimated to vary between 0.1–16/100,000 persons worldwide as of 2014. Extrapolation of abdominal surgery procedures indicate that approximately 3 million small bowel resection surgeries may be performed each year that include duodenectomies, Jejunectomies and ileectomies.
Short Bowel Syndrome Market: Diagnostic and Treatment Landscape
There are several methods for testing and diagnosing short bowel syndrome based on the symptoms and body functions. Blood chemistry tests such as albumin level test indicates if the body has reduced nutrient contents. Other tests include complete blood count, fecal fat test, small intestine x-ray and vitamin level blood tests. These laboratory tests are easily available and can be performed as an outpatient setting. High calorie diet, vitamin supplements, carbohydrates, protein and fat enriched foods are the essential treatment options for patients suffering from SBS. Under duress, a patient can also be treated with parenteral nutrition.
Medications for this disorder include drugs that slow bowel movement as a result of which, food remains in contact with the intestines for a longer time giving a chance for greater absorption of nutrients. In 2012, Gattex (teduglutide) has been one of the latest drugs to be approved by the FDA for SBS. Octreotide Acetate Injection is also considered as an off-label treatment drug for SBS. Sandostatin (Octreotide Acetate Injection) and somatostatin are manufactured by a number of companies such as TEVA pharmaceuticals, Wockhardt, Sandoz, Bioniche Pharma, Sun Pharmaceuticals, Sandostatin LAR and Novartis among several others.
Short Bowel Syndrome Market: Region-wise Insight
Geographically market is dominated by developed economic countries due to government intervention and presence of advanced healthcare facilities have essentially contributed in generating revenues. Currently in United States approximately 10,000 – 20,000 people in the United States suffers from short bowel syndrome. Increasing awareness and inclination of companies in gaining access to European marketing approval has significantly contributed in escalating market for SBS in European countries.
The market for SBS in Asia Pacific and Rest of the World is currently a growing stage. Owing to large population base and lack of hygienic food and burgeoning intestinal and digestion disorders is expected to grow the market in forthcoming years.
Short Bowel Syndrome Market: Competition Snapshot
Some of the leading players operating in the global Short bowel syndrome market comprises Takeda Pharmaceutical Company, NPS Pharmaceuticals, TEVA pharmaceuticals, Novartis International AG, XTEND and others.
In March 2013 the United States based NPS Pharmaceuticals reacquired worldwide marketing rights for short bowel syndrome drug Revestive from Takeda Pharmaceutical Company Limited. Additionally in September 2012, Revestive has already got European marketing authorization for treating adults with SBS. In December 2012 Teduglutide, a new drug got FDA approval for treating patients suffering with SBS and are dependent on parenteral nutrition or intravenous therapy.
The report offers a comprehensive evaluation of the market. It does so via in-depth insights, understanding market evolution by tracking historical developments, and analyzing the present scenario and future projections based on optimistic and likely scenarios. Each research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology developments, types, applications, and the competitive landscape.
The study is a source of reliable data on:
- Key market segments and sub-segments
- Evolving market trends and dynamics
- Changing supply and demand scenarios
- Quantifying market opportunities through market sizing and market forecasting
- Tracking current trends/opportunities/challenges
- Competitive insights
- Opportunity mapping in terms of technological break throughs
The regional analysis covers:
- North America (U.S. and Canada)
- Latin America (Mexico, Brazil, Peru, Chile, and others)
- Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, Luxembourg)
- Eastern Europe (Poland, Russia)
- Asia Pacific (China, India, Japan, ASEAN, Australia and New Zealand)
- Middle East and Africa (GCC, Southern Africa, North Africa)
TMR estimates the market size of various sectors using a combination of available data on the number and revenue of companies within each sub-sector and tiers of companies. The basic components used to determine market size and forecast for a specific product area are not only limited to supply-side data, but are also related to demand, industry trends, and the economic outlook. All the above data points are utilized to generate a statistical model targeting the sector marketplace. More than 300 TMR analysts across the world integrate these elements into a framework to determine the subsector market size for a base year and then forecast growth within each market.
TMR regularly interviews technology and business professionals as an ongoing effort to track the latest developments within each sector. These continuous surveys are stratified by company size and industry segment and weighted to reflect the global market place. All data are collected on an ongoing effort through a structured questionnaire rolled over the web or conducted via telephones. This provides the TMR team opportunities to request for detailed question sets, complex skip patterns, and real-time calculations, which assists respondents in answering questions involving numbers and percentages. Respondents, who are interviewed as experts, are screened and qualified based on certain criteria in addition to their decision-making authority and the scope of activity within their organizations.
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.