A DNA contains all the information required to build and maintain an organism. DNA molecules are composed of four nucleotides (A, T, G, C), and these nucleotides are linked together. Most of the informational content carried in nucleic acids (such as hman chromosomes) is in the form of linear order of bases i.e. sequence of the DNA or RNA. Determining the sequence of nucleotides (As, Ts, Cs, and Gs) in a piece of DNA/RNA is known as sequencing. It is a powerful diagnostic method in molecular diagnostics (MDx) lab toolkit for a number of applications.

Presently, there are two key sequencing technologies, Sanger sequencing and next-generation sequencing (NGS). Sanger sequencing (also known as dideoxy chain termination method) involves copying single-stranded DNA with chemically altered bases called dideoxynucleotides which when incorporated at the 3' end of the growing chain, terminate the chain selectively at A, C, G, or T. The terminated chains are then resolved by capillary electrophoresis. Sanger sequencing are primarily used to sequence individual pieces of DNA (such as DNA copied in PCR or bacterial plasmids). It gives high-quality sequence for relatively long stretches of DNA (up to 900 base pairs). Sanger sequencing is considered to be labor-intensive, expensive, and inefficient for larger-scale projects (such as the sequencing of an entire genome or metagenome). To accomplish such tasks, new, large-scale sequencing techniques such as next-generation sequencing (NGS) are deemed faster and less expensive.

The Sanger sequencing service market is projected to expand at steady pace in the next few years. Expansion of the Sanger sequencing service market can be attributed to growing demand for pharmacogenomics in drug discovery & development, declining prices of sequencing, technological advancements, increasing demand for affordable genotyping services, rising incidence and awareness on genetic diseases and personalized medicine, and high use of genetic analysis in animals and plants.

Technological advancements in the field of organ transplantations, favorable investments, funds, and grants by government bodies across the globe, increasing public-private investments, growing applications of genotyping, and rising number of soft tissue, solid organ, and stem cell transplantations are anticipated to drive the Sanger sequencing service market in the next few years.

In terms of application, the Sanger sequencing service market can be divided into shotgun sequencing, targeted gene sequencing, and others. Based on laboratory, the market can be bifurcated into web labs and dry labs. In terms of research, the Sanger sequencing service market can be segregated into in-house and outsourced. Based on end-user, the market can be categorized into pharmaceutical & biotechnology companies, academic & research institutes, and others.

In terms of region, the global Sanger sequencing service market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is estimated to account for the largest share of the global Sanger sequencing service market in 2017, followed by Europe and Asia Pacific. Key emerging markets such as China, India, and Brazil are expected to offer significant growth opportunities to stakeholders associated with the market. Rise in collaborations, partnerships, and agreements among market players, surge in government funding for translational research, improving healthcare infrastructure are likely to increase demand of Sanger sequencing services in the Asia Pacific region. Increase in competition in mature markets and relatively less-stringent regulations and data requirements as compared to developed nations are other key factors that makes Asia Pacific an attractive region for stakeholders.

Key players operating in the global Sanger sequencing service market include Eurofins Scinetific, Genscript Biotech, Biocompare, Inc., GENEWIZ, Source BioScience plc, Nucleics Pty. Ltd., First BASE Laboratories Sdn Bhd, MRC Protein Phosphorylation and Ubiquitylation Unit, LGC Ltd., and BaseClear.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
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  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

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The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

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Here's how Transparency Market Research helps the stakeholders and CXOs through the reports:

Inculcation and Evaluation of Strategic Collaborations: The TMR researchers analyze recent strategic activities like mergers, acquisitions, partnerships, collaborations, and joint ventures. All the information is compiled and included in the report.

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Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Sanger Sequencing Service Market