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Global Pulmonary Arterial Hypertension Market: Snapshot

Pulmonary arterial hypertension (PAH) is an uncommon type of progressive illness linked with high blood pressure. Nevertheless, the last few years, the increasing prevalence of PAH disorder due to rising risk factors such as HIV, sedentary lifestyle, tobacco and alcohol consumption, smoking, and other idiopathic conditions. As per the study conducted by World Health Organization and Centre for Disease Control and Prevention suggests that the prevalence of PAH is estimated to about 15 to 50 cases per million heads, and there is no everlasting cure for this disorder present in the market. Therefore, there is a high growth opportunities for the market to grow in the near future.

Various treatment are available in the market that helps in controlling and slowing down the growth of the diseases and improves the quality of life. In addition, the approval of few effective drugs and the occurrence of favorable pipeline are some of primary factors that drive the market growth. Favorable policies by government has contributed in boosting the demand in the global pulmonary arterial hypertension market.

According to Transparency Market Research, the global pulmonary arterial hypertension market is projected to rise at a promising CAGR of 17.90% over the forecast tenure between 2014 and 2020. In terms of revenue, the market is expected to touch US$5.19 bn by 2020.

Approval of New Drugs to Expand Market Growth

Based on drug class that includes prostacyclin and prostacyclin analogs, PDE-5 inhibitors, ERAs (endothelin receptor antagonists), and soluble guanylate cyclase (sGC) stimulators. In terms of value, ERAs segment is projected to dominate the market over the forecast tenure. On the other hand, during the forecast period prostacyclin and prostacyclin analogs segment is estimated to exceed the ERAs segment. This is because of the commercialization of novel drugs such as Uptravi (selexipag) in December 2015. Based on sGC stimulator, Adempas (riociguat) is the only certified drug used for treating PAH.

Presence of Favorable Pipeline Drugs to Boost Market in North America

Geographically, North America is dominated the global pulmonary arterial hypertension market and is projected to continue its dominance by contributing the major share by the end of 2020. North America is followed by Europe and both the regions are projected to grow remarkably throughout the forecast tenure. This is because the availability of commercialization of new PAH drugs coupled with the incidence of favorable pipeline drugs. In addition, growing awareness among the people of the regions for increasing availability of treatment for pulmonary arterial hypertension is also pushing the market growth.

Moreover, Asia Pacific also possess lucrative opportunities for the market. Countries like Japan, New Zealand, Australia, China, and India are projected to display high growth opportunities over the forecast period attributing to growing penetration of global players. Contrary to that, the rest of the world is expected to exhibit sluggish growth throughout the forecast tenure. The reason behind the sluggish growth is low awareness about the treatment and detection of PAH that is expected to obstruct the market to grow at its full potential.

The report has analyzed few of the leading companies in the market. Actelion Pharmaceuticals Ltd., Gilead Sciences Inc., Pfizer Inc., GlaxoSmithKline Plc., Novartis International AG, Bayer HealthCare, and United Therapeutics Corp are few prominent companies in the global pulmonary arterial hypertension market.

Pulmonary arterial hypertension (PAH) is a progressive disorder, characterized by high blood pressure in pulmonary arteries that carry blood from the heart to the lungs. PAH is a very rare condition that occurs when pulmonary arteries become narrow in diameter or get blocked. This report on the global pulmonary arterial hypertension (PAH) market offers an insightful and in-depth assessment of the current and future market potential of PAH drugs. The research study has been divided into eight chapters namely, preface, executive summary, global PAH market overview, global PAH market revenue by drug class, PAH market pipeline analysis, global PAH market revenue by geography, recommendations, and company profiles.
The executive summary chapter covers a market snapshot representing key findings from the study on the global PAH market. The market overview chapter of the report comprises qualitative analysis of the overall PAH market, considering factors determining market dynamics such as growth drivers, restraints, and opportunities. This chapter also includes a section on epidemiology of PAH. A section on the event impact analysis has also been provided in the market overview chapter of the report on the PAH market. In the competitive landscape section, the market revenue share of key players operating in the PAH market in terms of percentage in 2013 has been provided. The market share analysis of key players involved a study of the company’s product/service portfolio and sales revenue along with the geographical presence.
In chapter four, the global PAH market has been segmented into prostacyclin and prostacyclin analogs, endothelin receptor antagonists (ERAs), phosphodiesterase-5 (PDE-5) inhibitors, and soluble guanylate cyclase (sGC) stimulators, based on the commercially-available drug classes, to treat PAH. The market revenue size for each segment has been provided in terms of USD million in the chapter for the period from 2012 to 2020, along with the CAGR for the forecast period between 2014 and 2020, considering 2012 and 2013 as the base years. The chapter also provides qualitative analysis for each segment, based on factors such as market trends, recent developments, future outlook, and opportunities.
Chapter five deals with the pipeline analysis of the PAH market and comprises information such as major steps involved in the development and commercialization of a drug, tabular presentation of early-stage drug candidates, and extensive analysis and future sales projection of the late-stage drug candidate, Uptravi (selexipag).
Geographically, the global PAH market has been classified into four major regions namely, North America, Europe, Asia-Pacific, and Rest of the World (RoW). The market size and forecast for each of these regions along with the CAGR has been provided in the report.
The study on the global PAH market also suggests a list of recommendations for new companies aspiring to enter the market and existing companies willing to accentuate revenue shares. The report concludes with the profiles of major players in the global PAH market such as Actelion Pharmaceuticals, Ltd., Bayer HealthCare, Gilead Sciences, Inc., GlaxoSmithKline plc, Novartis International AG, Pfizer, Inc., and United Therapeutics Corporation. Each company profile in the report provides information under the heads: company overview, financial overview, product portfolio, business strategies, and recent developments.
The company overview section comprises basic information about the company such as major business areas, company’s brief history and its establishment year, number of employees, and geographical presence. In the financial overview section, annual revenue for the last three consecutive years (2011, 2012, and 2013) has been provided. The business strategies section mentions key strategies adopted by a company in the past to strengthen its position in the PAH market. The recent developments section shares information about the recent activities of the companies operating in the PAH market.
The global PAH market is segmented as follows:
Global Pulmonary Arterial Hypertension Market, by Drug Class
  • Prostacyclin and Prostacyclin Analogs
  • Endothelin Receptor Antagonists (ERAs)
  • Phosphodiesterase-5 (PDE-5) Inhibitors
  • Soluble Guanylate Cyclase (sGC) Stimulators
Pipeline Analysis: Pulmonary Arterial Hypertension Market
  • Early-stage Drug Candidates (Phase I & Phase II)
  • Late-stage Drug Candidates (Phase III & Registration Phase)
Global Pulmonary Arterial Hypertension Market, by Geography
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World (RoW)

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Pulmonary Arterial Hypertension Therapeutics