Primary cells are cells that are directly obtained from living tissue and are established for growth in vitro. These type of cells grow rapidly. There is a two-fold increase in the total number of cells in a culture. Primary cells obtained from different species (such as humans and animals) are used to find out potential differences between preclinical test in animals and humans. Before in vivo studies on mice or rats, these type of cells help design doses and decrease the number of animals required for preclinical testing. Human primary cells can be used to determine the accuracy of drug doses on the basis of data obtained from an animal model.
The global primary cells market is expected to expand substantially due to high prevalence of cancers, rise in cancer research, increase in research funding for the development of new cancer therapies, and rise in the number of collaborations & acquisitions. In cancer research, these cells are ideal models for cancer drug screening and biomarker discovery. Primary cells also help understand the biochemical pathways of cellular interactions. In addition, primary human cells have advantages over in vitro cell lines. They provide consistent tissue-specific responses in a biologically relevant microenvironment. In case of cell lines, they do not give false responses in a cellular context. Furthermore, primary human cells help decrease spending on animal models required for in vivo studies and are cost-effective. Pre-screened primary cells help to study in vivo signaling very closely. Due to this, biotechnology and pharmaceutical companies as well as CROs are increasingly shifting toward primary human cells for their drug discovery processes.
The global primary cells market can be segmented based on origin, type, end- user, and geography. Based on origin, the global primary cells market can be further divided into hematopoietic cells, gastrointestinal cells, skin cells, lung cells, liver cells, heart cells, renal cells, skeletal and muscle cells, and other primary cells. The hematopoietic cells segment dominates the global primary cells market due to an increase in cancer research globally. In terms of type, the market can be classified into human primary cells and animal primary cells. The human primary cells segment dominates the global market due to an increase in the incidence of cancer and rise in application areas of human stem cells. Based on end-user, the market can be categorized into life science research companies and research institutes.
In terms of geography, the primary cells market can be segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. Each region is sub-segmented into specific countries such as the U.S., Canada, the U.K., Germany, Brazil, China, India, and GCC countries. North America dominated the global primary cells market because of an increase in research, high prevalence of cancer related disorders, and presence of key players in the region. Asia Pacific is expected to be an attractive region of the market over the forecast period, due to an increase in health care awareness and rise in demand for advanced medical technology.
Key players operating in the primary cells market are Thermo Fisher Scientific, Merck KGaA, Lonza, Cell Biologics, PromoCell, ZenBio, Stemcell Technologies, AllCells, American Type Culture Collection, and Axol Biosciences, and other prominent players. In order to gain a competitive advantage in the industry, major players are actively involved in various growth strategies. Collaborations, agreements, partnerships, and new product launches are some of the important strategies adopted by market players. For instance, in May 2018, Lonza expanded its primary cells portfolio and added Kupffer cells, liver-derived endothelial cells, and hepatic stellate cells to its hepatocytes portfolio.
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