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Global Plasma Protease C1-inhibitor Treatment Market: Players Focus on Expanding Product Portfolio to Expand Outreach, says TMR

Posted on Oct 18, 2017

A fresh market intelligence study by Transparency Market Research (TMR) states that the business landscape of the global plasma protease c1-inhibitor treatment market is consolidated with intense competitive rivalry among leading players. TMR detects Shire plc led the global plasma protease C1-inhibitor treatment market in 2016. Key factors that account for its dominance are expanded product portfolio, acquisitions, and widespread market presence. Pharming Group N.V., CSL Limited, and Sanquin are some other key vendors that hold significant shares in the overall market for plasma protease C1-inhibitor treatment.

According to estimations of the TMR report, the demand in the global plasma protease c1-inhibitor treatment market will expand at a strong 20.0% CAGR for the forecast period of 2017 to 2025, for the market to be evaluated at US$7.9 bn by 2025-end considerably up from its evaluated worth of US$1.5 bn in 2016. Key vendors in the plasma protease c1-inhibitor treatment market are engaged in expanding their product portfolio and expand their distribution networks in order to penetrate global markets. This has mandated vendors to meet the regulatory standards set by governing bodies at national and international level.

In terms of drug class, the global plasma protease C1-inhibitor treatment market witness maximum demand from the segment of c1-inhibitors that led amongst other segments in 2016. Geography-wise, the report assesses North America to be the most profitable market for plasma protease c1-inhibitor treatment, which accounted for a demand worth US$1,510.5 mn in 2017.

plasma protease c1 inhibitor treatment market

 

Hefty Investment for Innovation in Inhibitor Drugs Boosts Growth

Growing investment for innovation in inhibitor drugs, promising pipeline drugs and novel therapies, and increasing awareness for hereditary angioedema (HAE) are primarily driving the plasma protease C1-inhibitor market through 2025.

One of the key drivers of the plasma protease C1-inhibitor treatment market is the increasing usage of plasma protease C1-inhibitor treatment drugs due to the increasing incidence of acute cases of hereditary angioedema (HAE) and prophylaxis. The emergence of C1-inhibitor is considered to be a major breakthrough among several drugs introduced in the plasma protease C1-inhibitor treatment market. Berinert is a C1-esterase inhibitor for acute HAE that received approval from the European Union in 2011. Haegarda, which is derived from C1-esterase inhibitor is approved in the U.S for routine prophylaxis as a preventive measure against HAE attacks in adolescents and adults.

Increasing practice of administering prophylactic treatment process for HAE patient, demand for a new route of administration of C1-inhibitor drugs, rising demand for administering drugs subcutaneously among HAE patients are some other growth drivers of the plasma protease C1-inhibitor treatment market.

Apart from this, commercialization of drugs such as Ruconest in emerging markets of Asia Pacific is likely to boost the C1-inhibitor segment in the upcoming years.

Research studies underway for the development of bradykinin B2 receptor antagonist for the treatment of HAE attacks is likely to propel the global plasma protease C1-inhibitor treatment market. At present, Firazyr is the only approved bradykinin B2 receptor for the treatment of acute HAE attack.  FR 173657 is another bradykinin B2 receptor that researchers are evaluating for efficacy for acute HAE attack.

The information presented here is based on the findings of a TMR report, titled “Plasma Protease C1-inhibitor Treatment Market (Drug Class- C1-inhibitors (C1-esterase Inhibitor and Recombinant Inhibitor), Kallikrein Inhibitor (Kalbitor), and Selective Bradykinin B2 Receptor Antagonist (Firazyr); Distribution Channel - Hospital Pharmacies and Independent Pharmacies and Outlets; Dosage Type - Lyophilized and Liquid/Injectable) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2017 - 2025.”

The global plasma protease C1-inhibitor treatment market is segmented as follows:

  • Global Plasma Protease C1-inhibitors Treatment Market, by Drug Class
    • C1-inhibitors
      • C1-esterase Inhibitor
      • Recombinant Inhibitor
    • Kallikrein Inhibitor (Kalbitor)
    • Selective Bradykinin B2 Receptor Antagonist (Firazyr)|
  • Global Plasma Protease C1-inhibitors Treatment Market, by Dosage Type
    • Liquid/Injectable
    • Lyophilized
       
  • Global Plasma Protease C1-inhibitors Treatment Market, by Distribution Channel
    • Hospital Pharmacies
    • Independent Pharmacies and Outlets
       
  • Global Plasma Protease C1-inhibitors Treatment Revenue, By Geography 
    • North America
      • U.S.
      • Canada
    • Europe
      • EU-5 Countries
      • BENELUX Countries
      • Rest of Europe
    • Latin America
      • Argentina
      • Brazil
      • Rest of Latin America
    • Rest of World
      • Australia
      • Israel
      • Rest of World Countries
         

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