Global Pemphigus Vulgaris Treatment Market: Overview

Pemphigus Vulgaris is a rare autoimmune disorder characterized by painful blisters on skin, lining of mouth, throat, nose and genitals. It usually affects middle-aged population including both men and women. Pemphigus Vulgaris occurs when body’s own immune system mistakenly attacks proteins in the layer of skin. The symptoms of pemphigus vulgaris includes development of painful blisters, and pinching sensation in on the skin. The blisters usually develops in the mouth first and then rupture forming painful sores. This continuous until entire lining of mouth is affected, causing difficulty in swallowing. Blisters also form on the skin and rupture creating painful wounds. Blisters once rupture become infected, the damaged skin oozes fluid and become prone to infections.  The diagnosis test for pemphigus vulgaris include histopathology, direct immunofluorescence, and indirect immunofluorescence. There is no permanent cure for pemphigus vulgaris, only symptomatic relief can be applied.

Global Pemphigus Vulgaris Treatment Market: Key Trends

Increase in awareness about influenza, improved health care infrastructure, increased R&D spending, technological advancements, increased investment by major players for the development of treatment, rich product pipeline, and increase in government initiatives are the major drivers of the global pemphigus vulgaris treatment market. However, a high cost of drug development and severe side effects associated with the treatment may acts as major restraints of the global market.

Global Pemphigus Vulgaris Treatment Market: Segmentation

The global pemphigus vulgaris treatment market can be segmented based on drug, route of administration, distribution channel and region. In terms of drug, the global market can be classified into prednisone, azathioprine, rituximab, cyclophosphamide, cyclosporine, and others. The prednosone segment dominated the market in 2018, and the trend is projected to continue during the forecast period. Expansion of the segment is attributed wide use of corticosteroids in the management of symptoms of pemphigus vulgaris. Based on route of administration, the global pemphigus vulgaris treatment market can be classified into oral and injectable. The oral segment dominated the market in 2018 and is expected to continue its dominance during the forecast period. Based on distribution channel, the global pemphigus vulgaris treatment market can be categorized into hospital pharmacies, retail pharmacies, and online pharmacies. The hospital pharmacies segment dominated the market, due to high preference for this channel of distribution. The segment is projected to maintain its leadership position from 2019 to 2027.

Global Pemphigus Vulgaris Treatment Market: Regional Analysis

In terms of region, the global pemphigus vulgaris treatment market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global pemphigus vulgaris treatment market in 2018 and is projected to constitute a significant market share during the forecast period. The market in the region is anticipated to expand at a rapid pace due to improved health care infrastructure and increased R&D spending in the region.  

According to National Organization for Rare Disorders (NORD) rare disease database, pemphigus is estimated to affect from 0.7-5 people per 1,000,000 per year in the general population and pemphigus vulgaris is the most common form of pemphigus in the U.S.

The market in Asia Pacific is anticipated to expand at a high CAGR in the next few years, due to technological advancements, increased research spending and improvement in health care infrastructure in developing countries.

Global Pemphigus Vulgaris Treatment Market: Competitive Landscape

Major players operating in the global pemphigus vulgaris treatment market include GlaxoSmithKline plc, Novartis AG, F. Hoffmann-La Roche Ltd, Vifor Pharma Management Ltd., Alexion, Genentech, Inc., argenx, and Principia Biopharma.

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