Drug delivery systems are becoming progressively sophisticated as pharmaceutical researchers obtain a good understanding of the biochemical and physiological parameters pertinent to their performance. The drug delivery through oral route is the standard technique in the pharmaceutical industry as it is considered as the most economic, convenient, and safest route of drug administration. The oral tablets are usually taken with water only with an exclusion of orally disintegrating tablets and chewing tablets. The oral tablets are released into the gastrointestinal tract and they are quickly absorbed into the blood circulation. Orally disintegrating tablet is a solid dosage form that quickly disintegrates or dissolves in the mouth within one minute and does not require water for swallowing.
Orally disintegrating tablets are becoming a choice of alternative for conventional tablets or capsules. The first orally disintegrating tablet was approved in 1996. Orally disintegrating tablets are known by many names such as fast dissolving, orodispersible, mouth-dissolving, and quick disintegrating tablets. They are uncoated tablets and they dispersed fast and are quickly absorbed. These tablets are intended to break down quickly in the mouth and the active pharmaceutical ingredients are absorbed in the gastrointestinal tract. They have been developed for various indications such as mental illness, migraine, and many other chronic medical conditions.
There are various methods available to develop orally disintegrating tablets such as tablet molding, freeze frying or lyophilization, spray drying, phase transition, mass-extrusion, cotton candy technology, direct compression method, and sublimation. The direct compression method is the most preferred method for manufacturing of orally disintegrating tablet as it provides adequate structural integrity and is cost effective in nature.
The global orally disintegrating tablet market is segmented on the basis of disease indication, distribution channel, and geography. On the basis of disease indication, the market is segmented into gastrointestinal diseases, central nervous system (CNS) diseases, oncology, and others. The CNS diseases segment is expected to gain high share of the market during the forecast period owing to increasing prevalence of CNS diseases such as depression, migraine, Parkinson’s disease, Alzheimer's disease, and schizophrenia. Other than CNS diseases, the gastrointestinal diseases segment is expected to expand at a high CAGR during the forecast period. On the basis of distribution channel, the global market is segmented into hospital pharmacy, retail pharmacy, drug store, and online pharmacy.
Geographically, the global market for orally disintegrating tablet is distributed over North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America is expected to register a high market share during the forecast period owing to increasing acceptance for technologically advanced products as well as rising prevalence of CNS diseases. Asia Pacific and Middle East & Africa are expected to expand at high CAGRs during the forecast period owing to low cost of orally disintegrating tablets and rise in awareness about various dosage form of tablet.
Tablets and capsules have certain limitations such as bitter taste, swallowing discomfort, and large size, especially for geriatric patients and children. These limitations of tablets and capsules are major driving factors for the orally disintegrating tablet market. In addition, rise in adoption of compliant dosage form and better taste have significantly increased the demand for orally disintegrating tablets, which is expected to drive the market growth during the forecast period.
However, there are hurdles in formulation of relatively high dose for orally disintegrating tablets. The difficulty level is high for the formulation of an orally disintegrating tablet with dose of 500 mg. Thus, the dose of a tablet is limited to 400 mg or less.
Key players operating in the global orally disintegrating tablet market include Eli Lilly and Company, Pfizer Inc., Merck & Co., Inc., Bristol-Myers Squibb Company, AstraZeneca, GlaxoSmithKline plc, Johnson & Johnson Services, F. Hoffmann-La Roche Ltd., Johnson & Johnson Private Limited, Mission Pharmacal Company, and Sciele Pharma among others.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
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The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.