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Global Oligonucleotide Therapeutics Market: Overview

Oligonucleotides refer to short chain DNA or RNA that are generally made by using automated synthesizers. In addition, purification of oligonucleotide is accomplished by anion exchange chromatography and it is followed by the techniques of freezing and desalting. In addition, synthesis of siRNA duplex oligonucleotide is done through an annealing step in which two purified strands of oligonucleotide are brought closer together in an equimolar ratio.  There exists much difference between oligonucleotide therapeutics and conventional medicine. The oligonucleotide therapeutics are capable of holding back the expression of specific genes. This factor results in the development of brand new oligonucleotides targeting certain genes and treating chronic diseases. Chemically modified artificial nucleic acids are utilized so as to develop these new oligonucleotide therapeutics. The developed artificial oligonucleotides come with better enhanced affinity and in-vivo stability to target mRNA. These factors are likely to act as growth factors for the global oligonucleotide therapeutics market.

Technology, application, and region are the three important parameters based on which the global oligonucleotide therapeutics market has been classified.

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Global Oligonucleotide Therapeutics Market: Notable Developments

The global oligonucleotide therapeutics market is marked with presence of quite a few prominent players, thereby making it a fairly competitive market for both the existing players and new entrants. These companies are forging, partnerships, collaborations, and mergers in an effort to gain larger revenue and market share. The following development is expected to play an important role in the market:

  • In Dec 2016, US-based Biogen LLC obtained nod from US Food and Drug Administration (FDA) for nusinersen’s new drug application. This new application involves use of Spinraza (nusinersen) injection for the purpose of treating  spinal muscular atrophy in adult and pediatric patients. In this process, a first of its kind antisense oligonucleotides molecule is used for treating spinal muscular atrophy.

Some of the prominent organizations in the global oligonucleotide therapeutics market comprise the below-mentioned:

  • miRagen Therapeutics, Inc.
  • Ionis Pharmaceuticals, Inc.
  • Merck & Co., Inc.
  • Gilead Sciences, Inc.
  • Biogen Inc.
  • Regulus Therapeutics Inc.

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Global Oligonucleotide Therapeutics Market: Key Trends

The global oligonucleotide therapeutics market is characterized by the presence of the following restraints, drivers, and opportunities.

Increased Research and Development Activities in the Field to Shoot Up Demand

The growth of the global oligonucleotide therapeutics market is likely to be driven by several factors. The demand for oligonucleotide therapeutics is likely to rise due to the presence of very few approved molecules. This factor offers a plethora of opportunities to the players in the global oligonucleotide therapeutics market for the development of new molecular entities. In addition, the technological upgradation and advancement of chemically synthesized oligonucleotides have resulted in the coming up of more extended and stable half-life molecules. There exists nearly 135 oligonucleotide therapeutics that are in various phases of development of drugs. This new products are likely to make addition to the already existing approved therapeutics that are available in the market today.

Global Oligonucleotide Therapeutics Market: Geographical Analysis

North America is likely to emerge as leading regional force in the global oligonucleotide therapeutics market throughout the tenure of assessment. Presence of several market leaders in the region is one of the major factors contributing toward the growth of the North America market. In addition, commercialization of new molecules and consolidation of market is likely to play important role for the development of the regional market in the years to come.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Oligonucleotide Therapeutics Market