Neuroprotective Agents Market: Introduction

Neuroprotection or prevention of neuronal loss is a complicated molecular process that is mediated by various cellular pathways. The most common conditions associated with nervous system involvement and intensive care unit (ICU) admission are trauma, shock, stroke, sepsis, traumatic brain injury (TBI), and ruptured brain aneurysm. Beneficial use of many agents has been reported in the prevention of neuronal cell death in animal models but supportive data from clinical trials is still lacking. Approximately 40% of energy produced is consumed in the maintenance of neuronal & glial integrity & the remainder is used for electrophysiologic activity. Neuroprotection refers to the use of therapies that reduce brain injury during acute stroke, through actions on the brain rather than by improving blood flow. Several neuroprotective agents have been tested under high quality of transition of preclinical results to clinical trial. For example, the first multicenter trial of experimental stroke research has been conducted to evaluate the effect of anti-CD49 d antibodies which inhibit the migration of leukocytes into the brain and reduce the infarct volume after a small cortical stroke.

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Key Drivers of Global Neuroprotective Agents Market

  • Increase in Incidence and Prevalence of Neurodegenerative Diseases

    Neurological disorders are an important cause of disability and death worldwide. The major neurodegenerative diseases, i.e., ‘the big three’, Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), account for considerable morbidity and mortality in the U.S. elderly population.

  • Increase in Stroke and Traumatic Central Nervous System Injuries

    Traumatic brain injuries and stroke cause secondary biochemical changes in brain. This results into tissue damage and associated neuronal cell death. Neuroprotective treatments limit secondary tissue loss and improve behavioral outcome in patients. This outcome is studied in several clinical trials.

North America to Hold Major Share of Global Neuroprotective Agents Market

North America is expected to hold major share of the global neuroprotective agents market during the forecast period. According to the Parkinson’s Foundation, 60,000 people in the U.S. are diagnosed of Parkinson’s each year. Hence, North America is the major market for these products. Worldwide, an estimated five to seven million people are living with Parkinson’s disease, which would increase the demand for neuroprotective drugs and spur research & development. The neuroprotective agents market in Asia Pacific is projected to expand at a rapid pace during the forecast period. This can be attributed to growing trend of preventive health care measures in North America.

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Key Players Operating in Global Market

The global neuroprotective agents market is highly concentrated, due to strong presence of a few key players. Several manufacturers hold major share in the market in their respective regions. Leading players operating in the global neuroprotective agents market are:

  • Bayer Healthcare, Eisai Inc.
  • GlaxoSmithKline Plc
  • Merck
  • Serono S.A.
  • Novartis AG
  • Teva Pharmaceutical Industries Ltd.
  • Genervon Biopharmaceuticals
  • NeuroVive Pharmaceutical
  • Ceregene, BHRPharma LLC
  • Neuren Pharmaceuticals
  • Allon therapeutics, Inc.
  • Bionure Inc.

Global Neuroprotective Agents Market: Research Scope

Global Neuroprotective Agents Market, by Drug

  • Cholinesterase Inhibitors
  • NMDA Receptor Antagonists
  • Anti-inflammatory & Anti-apoptotic Agents
  • Neurotropic Factors
  • Mitochondrial Dysfunction Regulators
  • Metal Ion Chelators
  • Ion Channel Modulators
  • Free Radical Trappers
  • Anti-excitotoxic Agents
  • Others

Global Neuroprotective Agents Market, by Indication

  • Alzheimer's Disease
  • Multiple Sclerosis
  • Parkinson's Disease
  • Ocular Degeneration (retinal disorders)
  • Amyotrophic Lateral Sclerosis (ALS)
  • Huntington's Disease
  • Neuropathies
  • Brain Injury
  • Other Disorders

Global Neuroprotective Agents Market, by Region

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia Pacific
    • China
    • Japan
    • India
    • Australia & New Zealand
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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