Liver carries out important functions in the body such as protein production, metabolizing of fat and carbohydrate, detoxification of drugs, alcohol, and environmental toxin. Liver disease is a broad term that covers all the potential problems that cause the liver fail to perform its designated function. The different types of liver diseases are hepatitis, cirrhosis, liver cancer, and liver abscess (collection of pus). Liver cirrhosis is a late stage of scarring of liver caused by liver disease and conditions such as chronic alcoholism, hepatitis, and non-alcoholic fatty liver disease. Signs and symptoms of liver cirrhosis include abdominal pain, fatigue, intestinal bleeding, jaundice, weakness, and weight loss. Liver cirrhosis can be broadly classified into hepatitis C-related cirrhosis, alcoholic cirrhosis, primary sclerosing cholangitis, and primary biliary cirrhosis. Approximately 20% to 30% of the subjects chronically infected with hepatitis C virus are likely to develop liver cirrhosis 15 to 25 years later. Alcoholic cirrhosis is an advanced form of liver disease caused due to alcohol consumption. About 10% to 15% of people with alcoholism develop liver cirrhosis.

Primary sclerosing cholangitis is characterized by cholestasis with inflammation in bile duct, eventually leading to liver cirrhosis. Primary biliary cirrhosis is an autoimmune disease of the liver that results in progressive disruption of the bile duct. Diagnosis of liver cirrhosis can be done by patient history, physical examination, laboratory test such as liver function test, hepatitis B and C test, imaging such as magnetic resonance elastography or transient elastography, MRI, and CT scan. However, liver cirrhosis can only be confirmed by liver biopsy. Liver cirrhosis cannot be cured; however, drugs prevent or delay further liver damage. These include chemotherapeutic drugs, targeted therapy, vaccine, antiviral drugs, immunoglobulin, corticosteroids, and immunosuppressant. Scientists are currently working to expand the treatment area for liver cirrhosis, but success has been limited. Currently, the phase II trial of IDN-6556 (emricasan) is underway on liver cirrhosis subjects. According to the Centers for Disease Control and Prevention, the global incidence of liver disease was 3.9 million in 2016. According to the World Health Organization (WHO), incidence of liver cirrhosis is rising in countries in Europe due to high consumption of alcohol.

Rise in prevalence of liver disease and rapidly changing lifestyles such as increase in alcohol consumption are projected to drive the global liver cirrhosis treatment market during the forecast period. Additionally, increase in awareness programs and rise in R&D investment for the development of new drug molecules are projected to propel the global liver cirrhosis treatment market in the near future. However, high cost of drug development and stringent government regulations are projected to restrain the global market during the forecast period.

The global liver cirrhosis treatment market can be segmented based on disease type, drug type, distribution channel, and region. In terms of disease type, the global market can be categorized into hepatitis C-related cirrhosis, alcoholic cirrhosis, primary sclerosing cholangitis, and primary biliary cirrhosis. Based on drug type, the global liver cirrhosis treatment market can be classified into chemotherapeutic drugs, targeted therapy, vaccine, antiviral drugs, immunoglobulin, corticosteroids, and immunosuppressant. In terms of distribution channel, the global market can be divided into online pharmacies, retail pharmacies, and hospital pharmacies.

Geographically, the global liver cirrhosis treatment market can be segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America is expected to account for the largest share of the global market due to favorable reimbursement scenario and higher health care spending. Europe is expected to be the second-largest market for liver cirrhosis treatment during the forecast period due to rise in awareness about new treatment options and developed regulatory framework. The liver cirrhosis treatment market in Asia Pacific is expected to grow at a rapid pace during the forecast period. Growth of the market in the region can be attributed to rise in prevalence of liver disease and improving health care infrastructure.

Key players operating in the global liver cirrhosis treatment market are Pfizer, Inc., Abbott Laboratories, Merck & Co., Inc., Novartis AG, F. Hoffmann-La Roche Ltd., Takeda Pharmaceuticals Company Ltd., and Zydus Pharmaceuticals Inc., among others 

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Liver Cirrhosis Treatment Market

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