Light-activated Therapies Market

Light-activated Therapies Market: Introduction

Light-activated therapy is also called as photo therapy, photodynamic therapy (PDT), photo radiation therapy, or chemotherapy. In this, special photosensitizing agents are used. Numerous advantages and disadvantages are associated with light-activated therapy.

It is less invasive than surgery, can be targeted very precisely, carries no long-term side effects, can be repeated at the same site several times are some of the advantages. Disadvantages include it cannot be used to treat cancers which are largely spread. PDT cannot be used on people with some blood-related diseases. Several types of diseases can be treated with the help of light-activated therapies such as acne; psoriasis; warts, which are caused by viruses; and skin cancers such as actinic keratosis & some other types of cancers. PDT’s biological effects may be least partially localised to the tumour, which might result in a higher concentration of the photosensitizers within the tumour in comparison to healthy cells.

The most common photosensitizers used are Riboflavin, Hypericin, Chlorin E6, Indocyanine green (ICG), and Curcumin.

Types of photodynamic therapies include chemiluminescence-mediated photodynamic therapy, Cerenkov radiation-induced photodynamic therapy, and bioluminescence-mediated photodynamic therapy.

• Chemiluminescence-mediated photodynamic therapy - In this therapy, special types of chemicals are used. They have varied applications such as bio imaging and chemo sensing & therapy. The most commonly used systems are luminol - H2O2 and oxalate - H2O2 ester.

• Bioluminescence-mediated photodynamic therapy - It is considered as a special type of CL, which involves the enzymatic oxidation of small molecule substrates, such as firefly luciferin and Renilla luciferase-coelenterazine systems.
• Cerenkov radiation-induced photodynamic therapy - This is an interaction between high speed charged particles with a surrounding medium

There are several PDT modalities such as superficial PDT, interstitial PDT, and deep PDT

• Superficial PDT: It comprises skin treatments with a low light penetration depth. It is also called as external PDT.
• Interstitial PDT: This can treat tumors beyond 1 cm supported by the use of needles, catheters and optical fibres, but utilizing conventional light sources, with its light penetration limits correspondingly as superficial PDT.
• Deep PDT: It includes an extensive variety of technologies which aims at a deeper penetration beyond what is attained by conventional light sources. This section possesses NIR radiation of up conversion materials with advanced photosensitizers excited with novel nonlinear optical techniques, ionizing radiation, self-illuminated compounds, and emerging implants.

Global Light-activated Therapies Market: Key Trends

• Increase in the cancer, skin-related diseases, and other diseases drives this market
• There is rise in the aesthetic market, and the cosmetic industry is getting importance because of such therapies
• On December 14, 2020, SonALAsense Pioneers announced a partnership and licence agreement with Insight, and a collaboration with an Ivy Brain Tumor Centre, to perform the first-in-man clinical trial for recurrent glioblastoma
• In December 2021, Biofrontera Inc. enrolled its first subject in Phase 1 Safety Study, which evaluates the photodynamic therapy with the three tubes of Ameluz
• A new deep tumour photodynamic tumour therapy was discovered by the Xiaolian Sun and Guoqiang Shao on September 1, 2021

North America to Dominate Global Light-activated Therapies Market

• In Asia Pacific, first-era porfimer sodium PDT and second-era talaporfin sodium PDT are authorized for medical insurance in Japan
• The U.S. Patent and Trademark Office issued a patent approval notice to Biofrontera Pharma GmbH titled "Lighting device for photodynamic therapy, it is a means of dealing with diseases of the skin and pores and has a light device" in December 2021, affiliated with a biopharmaceutical company that specializes in the marketing of dermatological products

Key Players Operating in Global Light-activated Therapies Market

The global light-activated therapies market is fragmented due to the presence of international and local players. A large number of manufacturers hold major share in their respective regions. Demand for the light-activated therapies has increased in emerging as well as developed markets owing to rise in awareness about technologically advanced products. Growth strategies adopted by leading players are likely to drive the global market.

Key players in global light-activated therapies market are-

• Advanz Pharma
• Biofrontera
• Biolitec Pharma
• Luzitin
• Nanospectra Biosciences
• Photoatomic
• Rakuten Medical Inc.
• Steba biotech
• Theralase
• Other Players

Global Light-activated Therapies Market: Research Scope

Global Light-activated Therapies Market, by Type

• Chemiluminescence-mediated Photodynamic Therapy
• Bioluminescence-mediated Photodynamic Therapy
• Cerenkov radiation-induced Photodynamic Therapy

Global Light-activated Therapies Market, by Product Type

• Light Bulbs
• Handheld Devices
• Light Box
• Others

Global Light-activated Therapies Market, by End-users

• Hospitals
• Clinics
• Homecare Settings
• Others

Global Light-activated Therapies Market, by Region

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia & New Zealand
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC Countries
  • South Africa

• Rest of Middle East & Africa