ELISpot and FluoroSpot Assays Market: Introduction
- ELISpot and FluoroSpot are the most commonly used immune assays for the functional assessment of the immune system at the single cell level using fluorophores labeled detection reagents. The cells are cultured on antibody coated plates that arrest specific target molecules released. Each spot detected in the assay represents a single cell, thereby providing qualitative and quantitative data for number of cells detected in the sample.
- ELISpot and Flourospot assays utilize sandwich ELISA technique to detect fluorescence. The process involves the use of a specific antibody coated over the microplate. Subsequently, the cells are transferred onto the microplate and placed in an incubator for a limited time period at 37 °C. Once incubation period is complete, an antigen antibody conjugate is formed, which is further processed to remove the unbound analyte. A blue black precipitate is formed, representing an individual analyte secreting cell. These assays are routinely employed for the detection and analysis of cytokines and other products secreted by a single cell level.
Key Drivers, Restraints, and Opportunities of Global ELISpot and FluoroSpot Assays Market
- Major drivers of the global ELISpot and FluoroSpot assays market are technological advancements, increase in incidence of chronic diseases, surge in awareness about timely diagnosis, rise in strategic collaborations, and increase in healthcare expenditure in developing countries across the world. Limited availability of high quality detection reagents, high sensitivity, and presence of more efficient technologies are expected to restrain the global market.
- Increasing vaccine research to tackle the drug-resistant strains challenge, rising global occurrence of chronic illnesses, and technological innovations in ELISpot and FluoroSpot analyzers and assay kits are key factors that drive the ELISpot and FluoroSpot assay market
- ELISpot is an important path to vaccine development for many illnesses, namely tuberculosis, HIV, malaria, AIDS, cancer, and flu. ELISpot test is an extensively used immunoassay in clinical studies to assess vaccine. Its reputation was based majorly on the higher sensitivity of the sample, statistical read-out, and ease of usage in both large screening and individual test. In fact, the test could be utilized to assess both T-cell reactions and vaccine-specific antibody-producing B cells.
- Expansion of the market is due to the rising global incidence of chronic diseases, increasing vaccine development to address the unmet challenge of antimicrobial resistance, and technological advancements in ELISpot and FluoroSpot assay kits and analyzers. The presence of alternative detection technologies, however, is anticipated to restrain the market during the forecast period.
North America to Capture Major Share of Global ELISpot and FluoroSpot Assays Market
In terms of region, the global ELISpot and FluoroSpot assays market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is anticipated to dominate the global market during the forecast period owing to an increase in patient population, rise in demand, presence of major manufacturers, better healthcare infrastructure, and surge in product launches. Europe was the second-largest market for ELISpot and FluoroSpot assays in terms of share in 2020. Increase in product approvals, rise in awareness, adoption of expansion strategies by global manufacturers in different regions to expand global presence along with strategic acquisition of local & medium-scale manufacturers to enhance product portfolio, and increase in research & development activities are expected to propel the market in Europe during the forecast period.
Asia Pacific is likely to offer significant opportunities in the ELISpot and FluoroSpot assays market during the forecast period. Rise in patient population, increase in healthcare expenditure, surge in presence of major manufacturers in the region, and mergers & acquisitions are projected to fuel the market in the region during the forecast period. The market in Latin America and Middle East & Africa is anticipated to expand at a steady pace during the forecast period. Rise in government initiatives to promote research & development, increase in healthcare infrastructure, and a surge in the demand are expected to augment the ELISpot and FluoroSpot assays market in these regions.
Key Players Operating in Global ELISpot and FluoroSpot Assays Market
The global ELISpot and FluoroSpot assays market is highly fragmented, with the presence of various key players. A large number of manufacturers hold a major share in their respective regions. Increase in focus on R&D by major manufacturers to introduce highly efficient kits for early disease diagnosis to improve their market position is anticipated to boost the growth of the market during the forecast period. Major players operating in the global ELISpot and FluoroSpot assays market are:
- Oxford Immunotec
- Cellular Technology Limited (CTL)
- Mabtech AB
- Becton, Dickinson and Company
- Abcam
- Bio-Techne
- Autoimmun Diagnostika GmbH
- Biotech Investissement Group
- Lophius Biosciences GmbH
- U-Cytech Biosciences
- Bio-Connect B.V.
- USA, Inc,
- Elabscience
- Thermo Fisher Scientific
- Others
Global ELISpot and FluoroSpot Assays Market: Research Scope
Global ELISpot and FluoroSpot Assays Market, by Product Type
- Analyzers
- Kits
- Accessories
- Others
Global ELISpot and FluoroSpot Assays Market, by Application
- Cancer research
- Drug discovery
- Disease diagnosis
- Others
Global ELISpot and FluoroSpot Assays Market, by End-User
- Hospitals
- Diagnostic laboratories
- Academic & research institutes
- Others
Global ELISpot and FluoroSpot Assays Market, by Region
- North America
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Australia & New Zealand
- Rest of Asia Pacific
- Latin America
- Brazil
- Mexico
- Rest of Latin America
- Middle East & Africa
- GCC Countries
- South Africa
- Rest of Middle East & Africa
