Barrett’s esophagus is one of the major complications of gastro-esophageal reflux disease (GERD) in which the normal squamous tissue lining the esophagus changes to the tissue resembling that of the intestine lining. This disease is caused by the damage to the esophagus from the chronic backwash of stomach contents (like enzymes and acid) that occurs with abnormal reflux. Over 10% of individuals with GERD develop Barrett’s esophagus. The intestinal cells in Barrett’s esophagus are more resistant to stomach acid than squamous cells, indicating that the tissue changes that occur are to protect the esophagus from acid exposure. This disease is commonly observed in men than in women, and is more common in white population as compared to Hispanic population, and is rare in Asian and black population. Barrett’s esophagus does not present any symptoms, and the patients’ seek treatment for GERD symptoms. Furthermore, Barrett’s esophagus is considered to be the primary risk factor for esophageal cancer. Over 12 million adults in the Americas are anticipated to be suffering from Barrett’s esophagus, of which over 1.5 million have only been diagnosed. In addition, it is estimated that over 0.5% of the patients with Barrett’s esophagus develop esophageal cancer.
Barrett’s esophagus can be classified into three categories -intestinal metaplasia without dysplasia; low-grade dysplasia; and high-grade dysplasia. Intestinal metaplasia without dysplasia is a condition in which the epithelial lining of the esophagus is replaced with the type of epithelium found in intestine. Low-grade dysplasia is a condition in which the cells appear abnormal on microscopic observation and this indicates the early-stage of pre-cancer of the esophagus. High-grade dysplasia indicates the advanced stage of pre-cancer of esophagus, and cells appear very abnormal on microscopic observation. Growing lifestyle changes leading to obesity, and increasing consumption of alcohol causing GERD among people, leading to Barrett’s esophagus is expected to contribute to the growth of the market. However, the asymptomatic condition of Barrett’s esophagus, patent expiry of drugs employed for the treatment of GERD, and the availability of over-the counter drugs might hamper future market growth.
The market for Barrett's esophagus treatment can be segmented into treatment type, distribution channel, and geography. The treatment for Barrett’s esophagus depends on the degree of dysplasia found in the esophageal cells. The treatment type for the disease includes medications and surgical treatment. Medications include proton pump inhibitors, antacids, H2 blockers, promotility agents, and others. Surgical therapies include radiofrequency ablation, photodynamic therapy, endoscopic spray cryotherapy, endoscopic mucosal resection, and surgery. The medications treatment for Barrett’s esophagus can be further segmented on the basis of distribution channel into hospital pharmacies, retail pharmacies, over the counter, and others. Surgical treatment for Barrett’s esophagus can be further segmented into end users that include hospitals, ambulatory surgical centers, and clinics, among others.
Geographically, the Barrett’s esophagus treatment market can be segmented into five regions, including North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America is anticipated to record highest market share, owing to the growing incidence and prevalence of the disease; focus of various organizations to create awareness among people; and well-developed healthcare infrastructure. Europe is anticipated to be the next dominant region in the Barrett’s esophagus treatment market. Growth in the region is anticipated to be adversely impacted due to sluggish economic growth. Asia Pacific is expected to record a robust CAGR during the forecast period, owing to significant contribution from emerging countries such as China and India.
The leading players in the Barrett’s esophageal treatment market include Addex Therapeutics, AstraZeneca, Plc., Rottapharm (Meda AB), Takeda Pharmaceutical Company Limited, Eisai Co. Ltd., Pfizer, Inc., Torax Medical, Mederi Therapeutics, Aros Pharma, Torax Medical, Inc., and C. R. Bard.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
2. Insights and Tools
The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.
3. Actionable Results
The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.