Global B-Cell Non-Hodgkin’s Lymphoma (NHL) Market: Overview

Non-Hodgkin’s lymphoma (NHL) is a group of heterogeneous proliferative malignancies. These malignancies usually occur in the B-cells, natural killer (NK) cells, or T cells in the lymphoid cell tissues such as bone marrow, spleen, thymus, and lymph nodes. In most cases, B-cell lymphoma is NHL cases with a broad range of blood cancers that occur in B-cells.

The global B-cell non-Hodgkin’s lymphoma market was revolutionized in the late 1990s due to the introduction of Roche’s Rituxan/MabThera drug. The market is still primarily dominated by the Rituxan drug. However, the patients suffering from B-cell non-Hodgkin’s lymphoma easily become stubborn to the Rituxan therapy or experience a relapse after receiving the first level of treatment. Such results have led to a surge in the research and development activities to address the issue.

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Global B-Cell Non-Hodgkin’s Lymphoma (NHL) Market: Notable Development

Some of the key developments in the global B-cell non-Hodgkin’s lymphoma market are listed below:

  • In June 2019, Genentech announced that it has received FDA approval for its Polivy™ drug. This drug is in combination with Rituxan® plus bendamustine and is used to treat adults with refractory or relapsed diffuse large B-cell lymphoma. This treatment drug is for patients who have received a minimum two therapies. Polivy™ was granted accelerated approval based on the complete rate of response.
  • In 2017, AstraZeneca and Aceta Pharma, the hematology research and development center of the company announced that the company has received the US FDA accelerated approval to CALQUENCE™. The drug is a kinase inhibitor used for the treatment of adults suffering from mantle cell lymphoma (MCL) and have undergone at least one therapy session.
  • In May 2019, AbbVie Inc. announced that the company has been successful in getting the US FDA approval for the VENCLEXTA® drug. It was approved as a drug for treating patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The patients need not have undergone any therapy session in order to use the approved drug.

Some of the key players in the global market include names such as Amgen, Bayer Inc., Calistoga, Celgene, and EMD Serono among others.

Global B-Cell Non-Hodgkin’s Lymphoma (NHL) Market: Drivers and Restraints

Some of the key driving factors for the growth of the global B-cell non-Hodgkin’s lymphoma market are listed below:

  • Growth CAR-T cell therapies: One of the key factors driving the growth of the global B-cell non-Hodgkin’s lymphoma market is the increasing therapies for chimeric antigen receptor (CAR)-T cells.
  • Launch of pipelines: The recent launch of six pipeline agents is also expected to play a key role in the growth of the global B-cell non-Hodgkin’s lymphoma market over the course of the given forecast period of 2019 to 2027.
  • Label Expansions: Another important factor that is driving the growth of the global B-cell non-Hodgkin’s lymphoma market is the label expansion of presently marketed therapies for treating B-cell NHL subtypes.

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Global B-Cell Non-Hodgkin’s Lymphoma (NHL) Market: Geographical Outlook

Global B-cell non-Hodgkin’s lymphoma market can be segmented into key geographical regions such as North America, Latin America, Asia Pacific, Europe, and the Middle East and Africa. Of these, the global market is expected to be dominated by North America owing to the rising number of people suffering from B-cell NHL. The market is expected to continue its dominance on account of early access to new technological and healthcare advances and growing awareness among people about B-cell NHL. 

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

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The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

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The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

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