Aldosterone receptor antagonist drugs are also known as MRAs, MCRAs, and anti-mineralocorticoids. Aldosterone receptor antagonist drugs are a drug class that inhibit the effects of aldosterone. Adrenal cortex of the adrenal gland produces a primary mineralocorticoid hormone, called aldosterone, in the body. Aldosterone increases sodium reabsorption by the colon, sweat glands, salivary glands, and kidneys. Aldosterone also increases excretion of potassium and hydrogen ions. Aldosterone receptor antagonist drugs block the effects of aldosterone, which means the aldosterone receptor antagonist drugs block the reabsorption of sodium that encourages water loss. This effect of blocking helps reduce the fluid around the heart, and thereby decreases elevated blood pressure in the patient’s body. Aldosterone receptor antagonist drugs are used for the treatment of heart failure, and high blood pressure in patients. Aldosterone receptor antagonist drugs also cause increase in passage of urine.
Aldosterone receptor antagonist drugs also help in the primary diagnosis and treatment of hyper-aldosteronism, hypokalemia, hirsutism, gender dysphoria, edema, alopecia, and acne. Acne is an inflammation of the skin that is characterized by superficial skin eruptions around the hair follicles. Alopecia is baldness, the absence of hair on the areas of the skin, where it should actually be present. Loss of hair as a result of radiation or chemotherapy administered to the head. Loss of hair from chemotherapy is temporary. Loss of hair from radiation is usually permanent.
Edema is the abnormal presence of fluid in large amounts in the intercellular tissue spaces of the body, usually demonstrable excessive fluid is accumulated in the subcutaneous tissues. Edema is localized, to increased vascular permeability, or lymphatic or venous obstruction. Edema is systemic, due to renal disease or heart failure. The designation of edema fluid is according to the site where the fluid is collected; for example, ascites. Gender Dysphoria is also called as gender identity disorder. It is a disorder where the person identifies himself or herself as the opposite gender. For example, a person who is a girl may actually act, and feel like a boy. The person feels very uncomfortable with the gender that they are actually born as.
Heart failure is the inability of the heart to pump blood, which contains nutrients and oxygen, to rest of the body. Hirsutism is the abnormal distribution of hair; for example, male pattern of hair distribution in women. Hypokalemia is a condition when the levels of potassium in serum or blood decrease or fall below permissible levels, which leads to various disease conditions. Primary hyper-aldosteronism is a disease condition where the hormone aldosterone is released in excess amounts by the adrenal glands. Increasing prevalence of primary hyper-aldosteronism diagnosis, in treatment of heart failure, high blood pressure, primary hyper-aldosteronism, hypokalemia, hirsutism, gender dysphoria, edema, alopecia, and acne boosts the demand for aldosterone receptor antagonist drugs. Increasing demand for the drugs is due to the growing geriatric population across the globe.
The global aldosterone receptor antagonist drugs market can be segmented based on disease type, distribution channel, and region. In terms of disease type, the market can be divided into heart failure, high blood pressure, primary hyper-aldosteronism, hypokalemia, hirsutism, gender dysphoria, edema, alopecia, and acne. Based on the distribution channel, the market can be classified into online pharmacies, retail pharmacies, and hospital pharmacies.
In terms of region, the market can be segmented into Asia Pacific, Latin America, Europe, North America, and Middle East & Africa. North America held a prominent share of the market in 2016 due to increased technological advancements in the research and development of the aldosterone receptor antagonist drugs in the region. Europe, followed North America, in terms of share of the market in 2016 due to the high prevalence of heart failure and high blood pressure indications the population of the region. The market in Asia Pacific is estimated to expand during the forecast period owing to the increase in government initiatives and awareness about aldosterone receptor antagonist drugs in the region. The market in Latin America, and Middle East & Africa is anticipated to expand during the forecast period due to the increasing prevalence of hypokalemia, hirsutism, gender dysphoria, edema, alopecia, and acne in these regions.
Key players operating in the global aldosterone receptor antagonist drugs market include Pfizer Inc. and Sun Pharmaceutical Industries Limited.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.
The study is a source of reliable data on:
- Market segments and sub-segments
- Market trends and dynamics
- Supply and demand
- Market size
- Current trends/opportunities/challenges
- Competitive landscape
- Technological breakthroughs
- Value chain and stakeholder analysis
The regional analysis covers:
- North America (U.S. and Canada)
- Latin America (Mexico, Brazil, Peru, Chile, and others)
- Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
- Eastern Europe (Poland and Russia)
- Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
- Middle East and Africa (GCC, Southern Africa, and North Africa)
The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.
A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.
Highlights of the report:
- A complete backdrop analysis, which includes an assessment of the parent market
- Important changes in market dynamics
- Market segmentation up to the second or third level
- Historical, current, and projected size of the market from the standpoint of both value and volume
- Reporting and evaluation of recent industry developments
- Market shares and strategies of key players
- Emerging niche segments and regional markets
- An objective assessment of the trajectory of the market
- Recommendations to companies for strengthening their foothold in the market
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.