Age-related macular degeneration is also called macular degeneration, ARMD, or AMD. AMD is a disease of retina that blurs the sharp central vision, which is important for various activities that involve looking straight ahead such as driving, using computer, watching television, sewing, and reading. In AMD, a part of retina called macula, which allows seeing fine details, is affected. AMD is a chronic eye disease that does not cause pain. It is mostly observed in patients aged above 50 years. AMD is a major cause of vision loss amongst the elderly people in the U.S. Rising geriatric population in the U.S. and other countries is expected to increase the prevalence of AMD significantly in the next few years. The disease is more prominent in developed countries and it accounts for 8.7% of blindness all over the world.
AMD is of two kinds viz. wet macular degeneration and dry macular degeneration. The first kind of AMD is more severe. It causes abnormal progression of blood vessels in the damaged part of macula, which damages the retinal vision. Though AMD is associated with aging, the research proposes that there also exists a genetic component to the disease. Scientists at Duke University (North Carolina, the U.S.) and other scientists have identified a strong relationship between AMD development and existence of gene variants such as complement factor H (CFH). Deficiency of the CFH gene is associated with nearly 50% of all potentially blinding cases of AMD. Researchers at the University of Columbia Medical Center and other researchers have identified that variants of an additional gene, complement factor B, may be involved in the AMD development. In around 74% of AMD patients that were studied, a specific variant of these genes has been found, which plays a key role in immune responses of the human body. At present, no treatment exists for dry AMD; however, existing therapies can delay the development of visual impairment and wet AMD.
The market for AMD is driven by increasing number of AMD patients throughout the world. According to the American Academy of Ophthalmology, in the U.S., around 11 million patients are affected by AMD and the prevalence of AMD is high in countries in Southeast Asia and sub-Saharan Africa, due to deficiency of vitamin A in these countries.
Growing reimbursement benefits for AMD drugs is another major driver for the age-related macular degeneration market. Depending on regular cost of the drug, Medicare postulated a National Reimbursement Rate in the U.S. In this condition, the agency pays almost 80% of the cost of bevacizumab and ranibizumab injections and the remaining 20% of the cost is co-paid. Medicare part B is a medical insurance, which includes insurance for eye diseases and diagnostic tests that also covers specific treatment conditions such as AMD. Lack of trained ophthalmologists, high cost of drugs for wet AMD, and associated high risk are some major challenges before the AMD market.
The age-related macular degeneration market can be broadly categorized on the basis of type of AMD, type of drug, route of administration, and geography. Based on type of AMD, the market can be segmented into wet AMD and dry AMD. Based on type of drug, it can be divided into Lucentis, Eylea, Avastin, Visudyne, and others. Based on route of administration, the market has been segmented into IV and intravitreal. Based on geography, the global AMD market can be divided into four regions viz. North America, Asia Pacific, Europe, and Rest of World.
Major players operating in the age-related macular degeneration market are Genentech, Inc. (a member of Roche Group), Pfizer, Inc., Valeant Pharmaceuticals International, Inc., Regeneron Pharmaceuticals, Bayer Healthcare (a subsidiary of Bayer AG), and Novartis AG.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
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The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
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The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
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The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
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