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Heart failure occurs when the heart is unable to pump enough blood to meet the body’s demand. This can be chronic, taking place slowly over time, or acute, occurring suddenly. Acute heart failure is defined as the rapid development of or change in symptoms pointing to heart failure requiring urgent medical attention and usually hospitalization. It is a physiological condition which adversely impacts the pumping efficiency of the cardiac muscles. Fluid accumulates around the heart and the ventricles fail to pump sufficient blood to all the organs. This eventually leads to deposition of the fluid in the lungs, abdomen, liver, and lower body. According to epidemiologic statistics by Novartis Pharmaceuticals, about 62 million adults worldwide died of heart failure in 2015 and this number is expected to rise. One person in five at the age of 40 runs the risk of developing heart failure, with over 1 million hospitalizations reported annually in Europe are accounted for by heart failure.

The increasing prevalence of diseases and unmet medical needs have created additional scope for the acute heart failure market. Drivers of this market include poor diet, lack of exercise, changing lifestyles, increasing stress, unhealthy weights, and rising levels of smoking & alcohol consumption. The incidence of one or more diseases such as diabetes mellitus, obesity, coronary artery diseases, sleep apnea, heart defects, irregular heartbeats, and kidney problems has a synergistic effect on the prevalence of acute heart failure, further contributing to the market.

The acute heart failure market can be segmented by type of treatment into the following categories: surgery, medicines, and medical devices. Common types of surgery include heart valve replacement, coronary artery bypass grafting surgery, and heart transplant. Classes of drugs used in the management of acute heart failure include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, beta blockers, digoxin, diuretics, aldosterone antagonists, nitrates, inotropic agents, and anticoagulants. ACE inhibitors, angiotensin II receptor blockers, and diuretics are major contributors to the acute heart failure market. Cardiorentis’ ularitide and Novartis’ serelaxin represent new treatment options for acute heart failure. Both are recombinant forms of human proteins intended to be used in addition to intravenous administered loop diuretics which are the current standard-of-care for acute heart failure.

Implantable left ventricular assist devices (LVAD), biventricular pacemakers, implantable cardioverter-defibrillators (ICDs), and heart pumps are the medical devices used in acute heart failure. Unmet medical needs such as safe & effective therapy and the increasing number of acute heart failure patients boost the demand for these devices. However, stringent regulatory requirements and the high cost of these devices negatively impact the market.

Geographically, the acute heart failure market is distributed over North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Among these, North America and Europe dominate the market. The prevalence of heart diseases is high in Eastern Europe and is increasing in parts of Asia and South America owing to the growing incidence of cardiac disorders, aging population, lack of exercise, diet-containing high fat & salt content, stress, and smoking. In Asia Pacific, China, Japan, Malaysia, and India constitute major shares in the acute heart failure market on account of the growing financial potential of individuals.

Key players in this market include Pfizer, GlaxoSmithKline plc. Novartis International AG, Biovail, Bristol Mayers Squibb Company, MSD, AstraZenica, Abiomed Inc., Symplmed, Berlin Heart GmbH, Biotronik SE & Co. KG, Boston Scientific Corp., HeartWare International Inc., Jarvik Heart Inc., LivaNova PLC, Medtronic plc, ReliantHeart Inc., St. Jude Medical Inc., and Cardiokinetix.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Acute Heart Failure Market

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