HER2 Antibodies Market

HER2 Antibodies Market (Type of Treatment Drugs: Trastuzumab, Lapatinib, Ado-trastuzumab Emtansine, Pertuzumab, and Everolimus) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2024-2034

HER2 Antibodies Market Outlook 2034

  • The global industry was valued at US$ 9.0 Bn in 2023
  • It is estimated to grow at a CAGR of 5.1% from 2024 to 2034 and reach US$ 15.7 Bn by the end of 2034

Analyst Viewpoint

Increase in prevalence of HER2-positive cancer due to environmental degradation, rise in adoption of unhealthy lifestyle, and surge in geriatric population is augmenting HER2 antibodies market growth. Overexpression of HER2 protein acts as a biomarker for medical professionals to diagnose cancers of the breast, ovaries, etc. at early stages.

Rise in investment in immunotherapy and other cancer therapeutics is also bolstering the HER2 antibodies market size. Advancements in delivery methods, assisted diagnostics, and improved patient comfort are gaining traction.

Additionally, innovation in manufacturing processes for cancer drugs enables accelerated healing, improved staff productivity, and optimal treatment efficiency. Prominent market players are expanding their footprint in novel regions and merging or acquiring other companies to expand their product portfolio and maintain a stronghold in the competitive landscape.

Market Introduction

HER2 (Human Epidermal Growth Factor Receptor 2) antibodies refer to a class of targeted immunotherapies designed specifically to treat cancers caused by HER2-positive genes.

Breast cancer is the most common cancer enabled by the HER2 protein. The protein is expressed overtly in certain cancers. It inhibits the normal functioning of organs and increases cancer cell growth. Anti-HER2 antibody therapeutics are facilitated intravenously, and at times, administered along with chemotherapy and hormonal therapy.

Advantages of HER2-inhibiting immunoglobulins include reduced side effects, minimal damage to healthy tissue, and precise target of cancer cells to enhance patient comfort and accelerate healing.

Recent HER2 antibodies market trends indicate an increase in focus on treatment efficacy, reduced resistance, and scaled applications. Major players are investing in the development of HER2-targeted antibody-drug conjugates, immune checkpoint inhibitors, and bispecific HER2 antibodies for enhanced efficacy.

Attribute Detail
Market Drivers
  • Increase in Prevalence of HER2-positive Cancer
  • Advancements in Immunotherapy and Biotechnology

Rise in Prevalence of HER2-positive Cancer Driving Market Progress

HER2 is a protein that promotes the growth of cancer cells in cases when the gene is overexpressed. Prevalence of HER2-positive breast cancer is increasing owing to factors such as unhealthy modern lifestyles, rise in environmental degradation, and drastic increase in the global old age population.

Amplification of the HER2 gene among medical practitioners is a predictive biomarker for several other cancers such as ovary, endometrium, bladder, lung, colon, and head and neck. These growing incidences enhance the need for HER2-positive cancer antibodies and HER2-targeted immunotherapy, thus propelling HER2 antibodies market statistics.

According to the World Health Organization, breast cancer led to the death of over 670,00 people in 2022. Breast cancer was the most common cancer in women in 157 countries out of 185 in 2022. An approximated 1.0% of breast cancer cases are among men

Advancements in Immunotherapy and Biotechnology Boosting HER2 Antibodies Market Revenue

Consistent innovations and investments in gene marking and therapeutics have led to increased efficacy, reliable delivery methods, and improved target mechanism for HER2 antigen-specific antibodies.

Advancements in the anti-HER2 therapy sphere include introduction of novel HER2 antibody engineering approaches, immuno-PET imaging with HER2 antibodies, and companion diagnostics for HER2-positive tumors.

Innovations focused on acceleration of healing, improving patient comfort, and offering personalized treatment options are gaining traction. Furthermore, investments in manufacturing processes in order to optimize costs, production, and staff productivity have been rising.

In 2021, the Cancer Research Institute awarded grants of more than US$ 28.5 Mn for immunotherapy research. More than 120 clinical trials were funded by the institute in 2021 to explore innovative cancer therapy methods. The institute also remarks that around US$ 648.0 Mn is spent to develop a single cancer drug.

Regional Outlook

Attribute Detail
Leading Region North America

North America constituted the largest HER2 antibodies market share in 2023. Availability of a robust healthcare infrastructure, rise in biotechnology research, and prevalence of breast cancer in the U.S., Canada, and Mexico are augmenting the market dynamics of the region.

According to the National Breast Cancer Foundation, in the year 2024, approximately 310,720 women and 2,800 men were estimated to be diagnosed with invasive breast cancer in the U.S. Around 43,000 people in the U.S. died due to complications caused by breast cancer in 2023.

As per the latest HER2 Antibodies market forecast, the industry in Europe is set to grow at a steady pace during the period between 2024 and 2034. Access to reliable and subsidized public healthcare and a surge in the geriatric population ate driving market development in the region.

According to data made publicly available by the European Commission, 355,000 women from the EU were diagnosed with breast cancer in 2020, with breast cancer accounting for one-third of all cancer cases among women.

Analysis of Key Players

Prominent companies operating in the global HER2 antibodies market are engaged in development of HER2 receptor blockers and precision HER2 targeting agents to cater to the rising cases of breast cancers in the developing world.

Research collaboration with other major players and regional expansion enable companies in the HER2 antibodies industry to reach newer demographics and expand their line of products. Merger & acquisition is also a vital and common strategy that allows companies to maintain a stronghold in the industry.

Novartis AG, Pfizer, Inc., F. Hoffmann-La Roche Ltd., Abnova Corporation, InvivoGen, Celltrion, Inc., Biocon, and Novus Biologicals are key players operating in this sector.

This HER2 antibodies market report highlights parameters such as company overview, financial overview, product portfolio, business strategies, and business segments of the companies mentioned above.

Key Developments

  • In February 2024, researchers from Tohoku University in Japan announced the development of a novel monoclonal antibody that specifically targets HER2-positive subtype of breast cancer. The innovation utilizes specialized proteins engineered to detect and bind to target with heightened accuracy.

HER2 Antibodies Market Snapshot

Attribute Detail
Market Value in 2023 (Base Year) US$ 9.0 Bn
Market Forecast Value in 2034 US$ 15.7 Bn
Growth Rate (CAGR) 5.1%
Forecast Period 2024-2034
Historical Data Available for 2020-2022
Quantitative Units US$ Bn for Value
Market Analysis The qualitative analysis includes drivers, restraints, opportunities, key trends, key market indicators, Porter’s Five Forces analysis, value chain analysis, and SWOT analysis. Furthermore, at the regional level, the qualitative analysis includes key trends, price trends, and key supplier analysis.
Competition Landscape
  • Prominent Players - Competition Dashboard and Revenue Share Analysis, 2023
  • Company Profiles (Details - Company Overview, Sales Area/Geographical Presence, Revenue, Strategy & Business Overview)
Format Electronic (PDF) + Excel
Market Segmentation
  • Type of Treatment Drugs
    • Trastuzumab
    • Lapatinib
    • Ado-trastuzumab Emtansine
    • Pertuzumab
    • Everolimus
Regions Covered
  • North America
  • Latin America
  • Asia Pacific
  • Europe
  • Middle East & Africa
Countries Covered
  • U.S.
  • Canada
  • U.K.
  • France
  • Spain
  • Germany
  • Italy
  • Japan
  • China
  • India
  • Australia & New Zealand
  • Brazil
  • Mexico
  • GCC Countries
  • Israel
  • South Africa
Companies Profiled
  • Novartis AG
  • Pfizer, Inc.
  • F. Hoffmann-La Roche Ltd.
  • Abnova Corporation
  • InvivoGen
  • Celltrion, Inc.
  • Biocon
  • Novus Biologicals
Customization Scope Available upon Request
Pricing Available upon Request

Frequently Asked Questions

How big was the global HER2 antibodies market in 2023?

It was valued at US$ 9.0 Bn in 2023

How is the HER2 antibodies business expected to grow by 2034?

It is projected to grow at a CAGR of 5.1% from 2024 to 2034

What are the key factors driving the demand for HER2 antibodies?

Increase in prevalence of HER2-positive cancer and advancements in immunotherapy and biotechnology

Which was the major region in the global HER2 antibodies industry in 2023?

North America dominated the global landscape in 2023

Who are the key HER2 antibody manufacturers?

Novartis AG, Pfizer, Inc., F. Hoffmann-La Roche Ltd., Abnova Corporation, InvivoGen, Celltrion, Inc., Biocon, and Novus Biologicals

    1. Preface

        1.1. Market Definition and Scope

        1.2. Market Segmentation

        1.3. Key Research Objectives

        1.4. Research Highlights

    2. Assumptions and Research Methodology

    3. Executive Summary: Global HER2 Antibodies Market

    4. Market Overview

        4.1. Introduction

            4.1.1. Product Definition

            4.1.2. Industry Evolution/Developments

        4.2. Overview

        4.3. Market Dynamics

            4.3.1. Drivers

            4.3.2. Restraints

            4.3.3. Opportunities

        4.4. Global HER2 Antibodies Market Analysis and Forecast, 2020-2034

    5. Key Insights

        5.1. Pipeline Analysis

        5.2. Key Product/Brand Analysis

        5.3. Key Mergers & Acquisitions

        5.4. COVID-19 Pandemic Impact on Industry

    6. Global HER2 Antibodies Market Analysis and Forecast, by Type of Treatment Drugs

        6.1. Introduction & Definition

        6.2. Key Findings/Developments

        6.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            6.3.1. Trastuzumab

            6.3.2. Lapatinib

            6.3.3. Ado-trastuzumab Emtansine

            6.3.4. Pertuzumab

            6.3.5. Everolimus

        6.4. Market Attractiveness Analysis, by Type of Treatment Drugs

    7. Global HER2 Antibodies Market Analysis and Forecast, by Region

        7.1. Key Findings

        7.2. Market Value Forecast, by Region, 2020-2034

            7.2.1. North America

            7.2.2. Europe

            7.2.3. Asia Pacific

            7.2.4. Latin America

            7.2.5. Middle East & Africa

        7.3. Market Attractiveness Analysis, by Region

    8. North America HER2 Antibodies Market Analysis and Forecast

        8.1. Introduction

        8.2. Key Findings

        8.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            8.3.1. Trastuzumab

            8.3.2. Lapatinib

            8.3.3. Ado-trastuzumab Emtansine

            8.3.4. Pertuzumab

            8.3.5. Everolimus

        8.4. Market Value Forecast, by Country, 2020-2034

            8.4.1. U.S.

            8.4.2. Canada

        8.5. Market Attractiveness Analysis

            8.5.1. By Type of Treatment Drugs

            8.5.2. By Country

    9. Europe HER2 Antibodies Market Analysis and Forecast

        9.1. Introduction

        9.2. Key Findings

        9.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            9.3.1. Trastuzumab

            9.3.2. Lapatinib

            9.3.3. Ado-trastuzumab Emtansine

            9.3.4. Pertuzumab

            9.3.5. Everolimus

        9.4. Market Value Forecast, by Country/Sub-region, 2020-2034

            9.4.1. Germany

            9.4.2. U.K.

            9.4.3. France

            9.4.4. Italy

            9.4.5. Spain

            9.4.6. Rest of Europe

        9.5. Market Attractiveness Analysis

            9.5.1. By Type of Treatment Drugs

            9.5.2. By Country/Sub-region

    10. Asia Pacific HER2 Antibodies Market Analysis and Forecast

        10.1. Introduction

        10.2. Key Findings

        10.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            10.3.1. Trastuzumab

            10.3.2. Lapatinib

            10.3.3. Ado-trastuzumab Emtansine

            10.3.4. Pertuzumab

            10.3.5. Everolimus

        10.4. Market Value Forecast, by Country/Sub-region, 2020-2034

            10.4.1. China

            10.4.2. Japan

            10.4.3. India

            10.4.4. Australia & New Zealand

            10.4.5. Rest of Asia Pacific

        10.5. Market Attractiveness Analysis

            10.5.1. By Type of Treatment Drugs

            10.5.2. By Country/Sub-region

    11. Latin America HER2 Antibodies Market Analysis and Forecast

        11.1. Introduction

        11.2. Key Findings

        11.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            11.3.1. Trastuzumab

            11.3.2. Lapatinib

            11.3.3. Ado-trastuzumab Emtansine

            11.3.4. Pertuzumab

            11.3.5. Everolimus

        11.4. Market Value Forecast, by Country/Sub-region, 2020-2034

            11.4.1. Brazil

            11.4.2. Mexico

            11.4.3. Rest of Latin America

        11.5. Market Attractiveness Analysis

            11.5.1. By Type of Treatment Drugs

            11.5.2. By Country/Sub-region

    12. Middle East & Africa HER2 Antibodies Market Analysis and Forecast

        12.1. Introduction

        12.2. Key Findings

        12.3. Market Value Forecast, by Type of Treatment Drugs, 2020-2034

            12.3.1. Trastuzumab

            12.3.2. Lapatinib

            12.3.3. Ado-trastuzumab Emtansine

            12.3.4. Pertuzumab

            12.3.5. Everolimus

        12.4. Market Value Forecast, by Country/Sub-region, 2020-2034

            12.4.1. GCC Countries

            12.4.2. South Africa

            12.4.3. Rest of Middle East & Africa

        12.5. Market Attractiveness Analysis

            12.5.1. By Type of Treatment Drugs

            12.5.2. By Country/Sub-region

    13. Competition Landscape

        13.1. Market Player - Competitive Matrix (by Tier and Size of Companies)

        13.2. Market Share Analysis, by Company (2023)

        13.3. Company Profiles

            13.3.1. Novartis AG

                13.3.1.1. Company Overview

                13.3.1.2. Product Portfolio

                13.3.1.3. SWOT Analysis

                13.3.1.4. Financial Overview

                13.3.1.5. Strategic Overview

            13.3.2. Pfizer, Inc.

                13.3.2.1. Company Overview

                13.3.2.2. Product Portfolio

                13.3.2.3. SWOT Analysis

                13.3.2.4. Financial Overview

                13.3.2.5. Strategic Overview

            13.3.3. F. Hoffmann-La Roche Ltd.

                13.3.3.1. Company Overview

                13.3.3.2. Product Portfolio

                13.3.3.3. SWOT Analysis

                13.3.3.4. Financial Overview

                13.3.3.5. Strategic Overview

            13.3.4. Abnova Corporation

                13.3.4.1. Company Overview

                13.3.4.2. Product Portfolio

                13.3.4.3. SWOT Analysis

                13.3.4.4. Financial Overview

                13.3.4.5. Strategic Overview

            13.3.5. InvivoGen

                13.3.5.1. Company Overview

                13.3.5.2. Product Portfolio

                13.3.5.3. SWOT Analysis

                13.3.5.4. Financial Overview

                13.3.5.5. Strategic Overview

            13.3.6. Celltrion, Inc.

                13.3.6.1. Company Overview

                13.3.6.2. Product Portfolio

                13.3.6.3. SWOT Analysis

                13.3.6.4. Financial Overview

                13.3.6.5. Strategic Overview

            13.3.7. Biocon

                13.3.7.1. Company Overview

                13.3.7.2. Product Portfolio

                13.3.7.3. SWOT Analysis

                13.3.7.4. Financial Overview

                13.3.7.5. Strategic Overview

            13.3.8. Novus Biologicals

                13.3.8.1. Company Overview

                13.3.8.2. Product Portfolio

                13.3.8.3. SWOT Analysis

                13.3.8.4. Financial Overview

                13.3.8.5. Strategic Overview

    List of Tables

    Table 01: Global HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    Table 02: Global HER2 Antibodies Market Size (US$ Mn) Forecast, by Region, 2020-2034

    Table 03: North America HER2 Antibodies Market Size (US$ Mn) Forecast, by Country, 2020-2034

    Table 04: North America HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    Table 05: Europe HER2 Antibodies Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034

    Table 06: Europe HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    Table 07: Asia Pacific HER2 Antibodies Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034

    Table 08: Asia Pacific HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    Table 09: Latin America HER2 Antibodies Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034

    Table 10: Latin America HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    Table 11: Middle East & Africa HER2 Antibodies Market Size (US$ Mn) Forecast, by Country/Sub-region, 2020-2034

    Table 12: Middle East & Africa HER2 Antibodies Market Size (US$ Mn) Forecast, by Type of Treatment Drugs, 2020-2034

    List of Figures

    Figure 01: Global HER2 Antibodies Market Size (US$ Mn) and Distribution (%), by Region, 2023 and 2034

    Figure 02: Global HER2 Antibodies Market Revenue (US$ Mn), by Type of Treatment Drugs, 2023

    Figure 03: Global HER2 Antibodies Market Value Share, by Type of Treatment Drugs, 2023

    Figure 04: Global HER2 Antibodies Market Value Share, by Region, 2023

    Figure 05: Global HER2 Antibodies Market Value (US$ Mn) Forecast, 2024-2034

    Figure 06: Global HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 07: Global HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

    Figure 08: Global HER2 Antibodies Market Value Share Analysis, by Region, 2023 and 2034

    Figure 09: Global HER2 Antibodies Market Attractiveness Analysis, by Region, 2023-2034

    Figure 10: North America HER2 Antibodies Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034

    Figure 11: North America HER2 Antibodies Market Attractiveness Analysis, by Country, 2024-2034

    Figure 12: North America HER2 Antibodies Market Value Share Analysis, by Country, 2023 and 2034

    Figure 13: North America HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 14: North America HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

    Figure 15: Europe HER2 Antibodies Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034

    Figure 16: Europe HER2 Antibodies Market Attractiveness Analysis, by Country/Sub-region, 2024-2034

    Figure 17: Europe HER2 Antibodies Market Value Share Analysis, by Country/Sub-region, 2023 and 2034

    Figure 18: Europe HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 19: Europe HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

    Figure 20: Asia Pacific HER2 Antibodies Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034

    Figure 21: Asia Pacific HER2 Antibodies Market Attractiveness Analysis, by Country/Sub-region, 2024-2034

    Figure 22: Asia Pacific HER2 Antibodies Market Value Share Analysis, by Country/Sub-region, 2023 and 2034

    Figure 23: Asia Pacific HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 24: Asia Pacific HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

    Figure 25: Latin America HER2 Antibodies Market Value (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034

    Figure 26: Latin America HER2 Antibodies Market Attractiveness Analysis, by Country/Sub-region, 2024-2034

    Figure 27: Latin America HER2 Antibodies Market Value Share Analysis, by Country/Sub-region, 2023 and 2034

    Figure 28: Latin America HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 29: Latin America HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

    Figure 30: Middle East & Africa HER2 Antibodies Market Size (US$ Mn) Forecast and Y-o-Y Growth (%), 2020-2034

    Figure 31: Middle East & Africa HER2 Antibodies Market Attractiveness Analysis, by Country/Sub-region, 2024-2034

    Figure 32: Middle East & Africa HER2 Antibodies Market Value Share Analysis, by Country/Sub-region, 2023 and 2034

    Figure 33: Middle East & Africa HER2 Antibodies Market Value Share Analysis, by Type of Treatment Drugs, 2023 and 2034

    Figure 34: Middle East & Africa HER2 Antibodies Market Attractiveness Analysis, by Type of Treatment Drugs, 2024-2034

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