Market Research Reports

Molecular Cytogenetics Market (Technologies: FISH and aCGH; Applications: Genetic Disorders, Cancer and Personalized Medicine) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019

96pages
Published Date: 2013-08-21
 

Description


Molecular cytogenetics field is witnessing a significant growth owing to the growing demand of FISH and aCGH techniques. The advent of FISH has managed to overcome the loopholes of conventional cytogenetics techniques; FISH enables the detection of both structural and numerical chromosomal rearrangements. The technique has been used significantly over the past few years for the detection of copy number variations and assessment of specific nucleic acids.

The research report on the molecular cytogenetics market provides detailed analysis of the global market and helps in understanding the driving forces for the growth of these technologies. The overall molecular cytogenetics market is categorized on the basis of technology in two major categories, namely, Fluorescent In-situ hybridization (FISH) and array based comparative genomic hybridization (aCGH). The market is also categorized on the basis of applications in which major areas such as genetic disorders, cancer, personalized medicine and others are covered. The market for all these segments is estimated for the period 2011 – 2019 in terms of value (USD Million).

The market has also been segmented geographically into four regions namely North America, Europe, Asia-Pacific, and Rest of the World (RoW). Market size and forecast has been provided for each of these regions. A detailed qualitative analysis of the factors responsible for driving and restraining the growth of the molecular cytogenetics market and future opportunities are provided in the report. 

Competitive landscape and end user analysis for the product types is highlighted and the market players are profiled with attributes such as company overview, financial overview, business strategies, product portfolio and recent developments. Market shares of the key players for 2012 are provided, and recommendations to accentuate market shares and ensure sustainability are also put forward in this report. Key market player profiles in this report include Abbott Laboratories, Affymetrix, Inc., Agilent Technologies, Inc., Applied Spectral Imaging, Life Technologies Corporation, Leica Biosystems, Illumina, inc., Oxford Gene Technology and others.

The global molecular cytogenetics market is segmented into the following categories:
  • Molecular Cytogenetics Market, by Technology
    • FISH
    • aCGH
  • Molecular Cytogenetics Market, by Applications
    • Cancer
    • Personalized Medicines
    • Genetic Disorders
    • Others
  • Molecular Cytogenetics Market, by Geography
    • North America
    • Europe
    • Asia-Pacific
    • RoW

Table of Contents


Table of Content

Chapter 1 Preface
1.1 Report Description
1.2 Market Segmentation
1.3 Research Methodology

Chapter 2 Executive Summary
2.1 Market Snapshot: Global Molecular Cytogenetics Market (2012 & 2019)
2.2 Global Molecular Cytogenetics Market, by Technology, 2012 (USD Million)
2.3 Global Molecular Cytogenetics Market, by Application, 2012 (USD Million)

Chapter 3 Market Overview
3.1 Introduction
3.2 Market Drivers
      3.2.1 Introduction of advanced technologies
      3.2.2 Rising incidence of cancer cases
3.3 Market Restraints
      3.3.1 Issues with medical reimbursement
3.4 Market Opportunities
      3.4.1 Advent of Next Generation Sequencing
      3.4.2 Tapping the emerging economies
3.5 Porter’s Five Forces Analysis
      3.5.1 Bargaining power of buyers
      3.5.2 Bargaining power of suppliers
      3.5.3 Threat of new entrants
      3.5.4 Threat of substitutes
      3.5.5 Competitive rivalry
3.6 Market Attractiveness Analysis
3.7 Market Share Analysis, by Key Players (%)
      3.7.1 Global Molecular Cytogenetics Market Share Analysis, by Key Players (%)
3.8 End User Analysis
      3.8.1 Global Molecular Cytogenetics End User Analysis

Chapter 4 Molecular Cytogenetics Market, by Technology
4.1 Overview
      4.1.1 Global Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
4.2 Fluorescence in situ hybridization (FISH)
      4.2.1 Global FISH Market, 2011 – 2019 (USD Million)
4.3 Array-Comparative Genomic Hybridization (aCGH)
      4.3.1 Global aCGH Market, 2011 – 2019 (USD Million)

Chapter 5 Molecular Cytogenetics Market, by Applications
5.1 Overview
      5.1.1 Global Molecular Cytogenetics Market, by Application, 2011 – 2019 (USD Million)
5.2 Cancer
      5.2.1.1 Global Cancer Application Market, 2011 – 2019 (USD Million)
5.3 Personalized Medicines
      5.3.1.1 Global Personalized Medicine Application Market, 2011 – 2019 (USD Million)
5.4 Genetic Disorders
      5.4.1.1 Global Genetic Disorder Application Market, 2011 – 2019 (USD Million)
5.5 Others (Neurological, Cardiovascular and Infectious Diseases)
      5.5.1.1 Global Others Application Market, 2011 – 2019 (USD Million)

Chapter 6 Molecular Cytogenetics Market, by Geography
6.1 Overview
      6.1.1 Global Molecular Cytogenetics Market, by Geography, 2011 – 2019 (USD Million)
6.2 Comparative Analysis: Molecular Cytogenetics Market, by Geography, 2012 & 2019 (Value %)
6.3 North America
      6.3.1 North America Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
      6.3.2 North America Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
6.4 Europe
      6.4.1 Europe Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
      6.4.2 Europe Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
6.5 Asia-Pacific
      6.5.1 Asia-Pacific Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
      6.5.2 Asia-Pacific Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
6.6 RoW
      6.6.1 RoW Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
      6.6.2 RoW Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)

Chapter 7 Recommendations
7.1 Investment in emerging economies
7.2 Mergers and Acquisitions

Chapter 8 Company Profiles
8.1 Abbott Laboratories
      8.1.1 Company Overview
      8.1.2 Financial Overview
      8.1.3 Product Portfolio
      8.1.4 Business Strategies
      8.1.5 Recent Developments
8.2 Affymetrix, Inc.
      8.2.1 Company Overview
      8.2.2 Financial Overview
      8.2.3 Product Portfolio
      8.2.4 Business Strategy
      8.2.5 Recent Developments
8.3 Agilent Technologies, Inc.
      8.3.1 Company Overview
      8.3.2 Financial Overview
      8.3.3 Product Portfolio
      8.3.4 Business Strategies
      8.3.5 Recent Developments
8.4 Applied Spectral Imaging, Inc.
      8.4.1 Company Overview
      8.4.2 Financial Overview
      8.4.3 Product Portfolio
      8.4.4 Business Strategy
8.5 BI Biological Industries
      8.5.1 Company Overview
      8.5.2 Financial Overview
      8.5.3 Product Portfolio
      8.5.4 Business Strategy
8.6 Bio-Rad Laboratories
      8.6.1 Company overview
      8.6.2 Financial Overview
      8.6.3 Product Portfolio
      8.6.4 Business Strategies
      8.6.5 Recent Developments
8.7 CytoTest Inc.
      8.7.1 Company Overview
      8.7.2 Financial Overview
      8.7.3 Product Portfolio
      8.7.4 Business Strategy
8.8 Cytognomix, Inc.
      8.8.1 Company Overview
      8.8.2 Financial Overview
      8.8.3 Product Portfolio
      8.8.4 Recent Developments
8.9 F. Hoffmann-La Roche Ltd.
      8.9.1 Company Overview
      8.9.2 Financial Overview
      8.9.3 Product Portfolio
      8.9.4 Business Strategy
      8.9.5 Recent Developments
8.10 Illumina Inc.
      8.10.1 Company Overview
      8.10.2 Financial Overview
      8.10.3 Product Portfolio
      8.10.4 Business Strategies
      8.10.5 Recent Developments
8.11 LEICA BIOSYSTEMS
      8.11.1 Company Overview
      8.11.2 Financial Overview
      8.11.3 Product Portfolio
      8.11.4 Business Strategy
      8.11.5 Recent Development
8.12 Life Technologies Corporation
      8.12.1 Company Overview
      8.12.2 Financial Overview
      8.12.3 Product Portfolio
      8.12.4 Business Strategy
      8.12.5 Recent Developments
8.13 Oxford Gene Technology
      8.13.1 Company Overview
      8.13.2 Financial Overview
      8.13.3 Product Portfolio
      8.13.4 Business Strategy
      8.13.5 Recent Developments
8.14 PerkinElmer, Inc.
      8.14.1 Company Overview
      8.14.2 Financial Overview
      8.14.3 Product Portfolio
      8.14.4 Business Strategy
      8.14.5 Recent Developments
8.15 SciGene Corporation
      8.15.1 Company Overview
      8.15.2 Financial Overview
      8.15.3 Product Portfolio

List of Figures

FIG. 1 Molecular Cytogenetics: Market Segmentation
FIG. 2 Global Molecular Cytogenetics Market, by Technology, 2012 (USD Million)
FIG. 3 Global Molecular Cytogenetics Market, by Applications, 2012 (USD Million)
FIG. 4 Porter’s Five Forces Analysis: Global Molecular Cytogenetics Market
FIG. 5 Market Attractiveness Analysis: Global Molecular Cytogenetics Market, by Geography
FIG. 6 Molecular Cytogenetics: Market Share, by Key Players, 2012 (%)
FIG. 7 Molecular Cytogenetics: End User Analysis, 2012
FIG. 8 FISH Procedural Steps
FIG. 9 Global FISH Market, 2011 – 2019 (USD Million)
FIG. 10 Global aCGH Market, 2011 – 2019 (USD Million)
FIG. 11 Global Cancer Application Market, 2011 – 2019 (USD Million)
FIG. 12 Global Personalized Medicine Application Market, 2011 – 2019 (USD Million)
FIG. 13 Global Genetic Disorders Application Market, 2011 – 2019 (USD Million)
FIG. 14 Global Others Applications Market, 2011 – 2019 (USD Million)
FIG. 15 Comparative Analysis: Molecular Cytogenetics Market, by Geography, 2012 & 2019 (Value %)
FIG. 16 Abbott Laboratories, Annual Revenues: 2010 – 2012 (USD Billion)
FIG. 17 Affymetrix, Inc. Annual Revenues: 2010 – 2012 (USD Million)
FIG. 18 Agilent Technologies, Inc., Annual Revenue: 2010 – 2012 (USD Million)
FIG. 19 Bio-Rad Laboratories, Annual Revenues: 2010 – 2012 (1 Euro = 1.32 USD) (USD Million)
FIG. 20 F. Hoffmann-La Roche Ltd., Annual Revenues: 2010 – 2012 (1 Swiss Franc = 1.09 USD) (USD Billion)
FIG. 21 Illumina Inc., Annual Revenues: 2010-2012 (USD Million)
FIG. 22 Life Technologies Corporation, Annual Revenues: 2010 – 2012 (USD Million)
FIG. 23 PerkinElmer Inc., Annual Revenues: 2010 – 2012 (USD Billion)

List of Tables

TABLE 1 Market Snapshot: Global Molecular Cytogenetics Market (2012 & 2019)
TABLE 2 Global Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
TABLE 3 Global Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
TABLE 4 Global Molecular Cytogenetics Market, by Geography, 2011 – 2019 (USD Million)
TABLE 5 North America Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
TABLE 6 North America Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
TABLE 7 Europe Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
TABLE 8 Europe Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
TABLE 9 Asia-Pacific Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
TABLE 10 Asia-Pacific Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)
TABLE 11 RoW Molecular Cytogenetics Market, by Technology, 2011 – 2019 (USD Million)
TABLE 12 RoW Molecular Cytogenetics Market, by Applications, 2011 – 2019 (USD Million)

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Free Market Analysis


Molecular cytogenetics refers to the study of chromosomal structures with use of molecular techniques. The technique provides a combination of both molecular and cytological approach to research and diagnosis. Molecular cytogenetics is being considered as an indispensable tool for the diagnosis and research of numerous chromosomal aberrations. The technique is preferred over traditional chromosomal banding technique as traditional techniques provide low resolution level and may escape detection of copy number variations.

The breakthrough in the molecular cytogenetics technologies such FISH and aCGH are providing new dimensions to the areas of research and molecular diagnostics. These techniques are considered as invaluable tool for gene mapping, gene discovery and complex disease trait analysis. Molecular cytogenetics facilitates diagnosis and prognosis of diseases associated with hematological malignancies and solid tumors at molecular level. Likewise, alongwith diagnosis and prognosis of tumors, the technique is facilitating the practice of personalized medicines. The global molecular cytogenetics market was valued at USD 469.2 million in 2012 and is expected to grow at a CAGR of 23.4% from 2013 to 2019 to reach at an estimated value of USD 1.9 billion in 2019. 

Currently, aCGH technique is gaining momentum as compared to FISH technique owing to higher resolution over other traditional banding techniques. Earlier, where cytogenetics field was limited to identification of chromosome structure, it has now expanded its horizons to assessment of structural and functional genetic anomalies. FISH characterized by its ability to interpret information at genome level currently, captures the lion’s share of the molecular cytogenetics market. The technique has been utilized over the past decade for identification of various diseases and in suggesting accurate treatment options to the physicians. The technique is known for its accuracy, speed, sensitivity and high resolution over the traditional methods. Further, owing to its growing importance in laboratories the technique is backed by technological advancements such as improved fluroscence microscopes and digital imaging. Moreover, the technique is also supported by ongoing developments in the field of genomics and bioinformatics. FISH has become an essential tool for the validation of diseases and is being extensively used in laboratories and hospitals.

aCGH technique is rapidly growing with a CAGR of more than 20% and is poised to lead the market in the future. aCGH technique is a high resolution tool and its uniqueness lies in performing thousands of experiments in one array. aCGH has facilitated clinicians to move from sequential diagnostics to parallel diagnostics which provides accurate analysis at one time. aCGH technique is gradually evolving and is expected to surpass FISH technique in the coming years owing to its accuracy and rapid results. aCGH in the next few years would become the primary screening tool while FISH is expected to become more of a validation tool. Moreover, the technology is highly being preferred over FISH owing to its ability to detect several genomes simultaneously. As aCGH provides high resolution copy number variations the technology has numerous application areas in medicine.

Geographically, North America accounts for the largest market for molecular cytogenetics followed by Europe. Growth in these countries is driven by host of factors such as increased level of public awareness, coupled with a large pool of research laboratories. Moreover, growth in the market is also increasing due to rise in cancer incidences and development of personalized medicines. Asia-Pacific is likely to emerge as the fastest growing market during the analysis period. The market in this region is influenced owing to expanding population base, and rising public awareness. Similarly, culture of consanguineous marriage which increases the chances of inheritance of genetic disorders is accelerating the market growth. Suppliers can therefore look forward to the opportunities for molecular cytogenetics techniques in these emerging nations.

Key players in the molecular cytogenetics market include Abbott Laboratories, Applied Spectral Imaging, Affymetrix, Inc., Agilent Technologies, Inc., Illumina, Inc., Life Technologies Corporation, among others.

global-molecular-cytogenetics-market-by-applications-2012
 

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