Global X-ray Crystallography Market: Snapshot
The global X-ray crystallography market is prognosticated to be popularized by the application of the technique for researching protein structures and assessing protein-ligand interactions, protein- nucleic acid complexes, viruses, and enzymes. Besides determining biological macromolecules and protein structure, X-ray crystallography could be used to reconstruct molecular crystalline structures. Commercially, the technique could be engaged to examine crystalline structures in jewels and artefacts, electronic chips, cosmetics, bones and teeth, and DNA and conduct pharmaceutical drug discovery.
2014 was declared as the International Year of Crystallography (IYCr2014) by United Nations Educational, Scientific, and Cultural Organization (UNESCO) for celebrating the significant role of the technique and promoting more discovery and research in the same field. With the course of time, the global X-ray crystallography market is prophesied to receive a strong impetus on the back of newer applications broadening the commercial employment of the technique. X-ray crystallography is swiftly becoming a precise and powerful technique for analyzing crystalline single structures.
Research organizations and academics associated with material and chemical sciences are foreseen to be key end users of X-ray crystallography. However, other prime end users of the technique could be manufacturing firms involved in demanding research and development activities conducted in the physical and atomic science domain. More opportunities for increasing the demand in the global X-ray crystallography market are forecasted to arise from the engagement of players in research and development activities performed in the fields of cosmetic, pharmacy, and biotechnology. The clinical application of examining atomic composition of crystalline structures in a human body could help the technique gain extensive recognition in hospitals and research laboratories.
X-ray crystallography is primarily utilized for determining arrangement of particles inside crystals. The diffraction of x-rays, after they are projected on a crystal, are measured by the crystallographer to determine the electron density of the crystal and also provides a three-dimensional image of the same. X-ray crystallography has been instrumental in determining types and lengths of chemical bonds and size of atoms among others. This is achieved primarily because crystal forms are available for semiconductors, metals, minerals, proteins and salts among others. An X-ray crystallography functions by projecting x-rays on a crystal held between the x-ray source and a screen. The diffracted rays are captured on the screen as dotted patterns. Fourier transformation mathematics is then applied for obtaining the shape of the crystal from the pattern obtained on the screen. X-ray crystallography is very important for synthesis of new drugs and medicines as it aids in determining the structure of their precursors.
Some of the major factors fuelling the demand for the global X-ray crystallography market is the increasing research and development being conducted for better drugs and medicines by the pharmaceutical industry. Factors such as development of multi-drug resistant bacteria, constantly evolving pathogenic viruses and quest for developing drugs for various types of cancer among others have been fuelling the demand for newer medicines. Such increase in demand for medicines has in turn fuelled the demand for x-ray crystallography since it aids in developing structure-based drug design for targeting specific bio-molecules among others. Additionally, x-ray crystallography is also been used for obtaining quantitative results of samples across industry verticals such as cement and wood among others. Such varied applications have also been positively impacting the growth of x-ray crystallography market. However, requirements for developing crystals, of the product to be studied, prior to utilizing x-ray crystallography have been a significant restraining factor. Also development of newer technologies such as x-ray free electron lasers can pose a threat for the x-ray crystallography market. The increasing research and development for advanced targeted drug delivery systems poses good opportunity for the global x-ray crystallography market.
By product type, the global x-ray crystallography market can be segmented into instruments, reagents and services. Instruments segment is expected to remain the dominant segment during the forecast period. By applications, the x-ray crystallography market can be further segmented in to academic research, industrial, mineralogy & metallurgy, chemicals, pharmaceuticals and others. Pharmaceuticals segment is expected to remain the largest segment in 2023. By geography, the global x-ray crystallography market can be segmented into North America, Europe, Asia-Pacific (APAC) and rest of the world (RoW). North America can be expected to remain the leader in x-ray crystallography market globally, during the forecast period.
Some of the key companies leading the x-ray crystallography market globally are Thermo Fisher Scientific, Inc. (U.S.), Rigaku Corporation (Japan), Bruker Corporation (U.S.), Anton Paar GmbH (Austria), Danaher Corporation (U.S.), MiTeGen, LLC (U.S.), PerkinElmer, Inc. (U.S.), PANalytical B.V. [Spectris] (The Netherlands), Molecular Dimensions (U.K.), and Olympus Corporation (Japan) among others.
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