Global Uveal Melanom Market: Overview
Uvea is present posterior to sclera and the cornea and has three parts namely, iris, ciliary body and choroid. Uveal melanoma is referred as the cancer of the parts of eye including the iris choroid and ciliray body. It is the condition in which the tumors arise from the melanocytes residing within the uva responsible for the color of the eye. Though is a rare condition, it is most common type of intraocular malignancy in adults. The uveal melanoma treatment depends on various factors most important being the size of the tumor. This type of melanoma is completely asymptomatic in the initial stages. On enlargement of tumor with time, certain changes may be observed such as distortion of pupil, decreased visibility due to secondary retinal detachment and blurred vision. Risk factors for this kind of cancer include fair complexion, blue, and green or light colored eyes, and older age. The role of inherited genetic mutation in uveal melanoma is yet unknown. According to the American Cancer Society, about nine of 10 melanomas of the eye develop in the choroid. The society also reports about 2,730 new cases in 2014 of uveal melanoma in the U.S.
Global Uveal Melanom Market: Segment Outlook
The global uveal melanoma market can be segmented based on diagnostic tests, therapy type, location type and geography. Location type can be further classified as iris melanoma, choroid melanoma and ciliary melanoma. Primary treatment involves enucleation i.e. removal of the affected eye. However this has now been replaced by radiation therapies such as plaque brachytherapy in the developed countries. Other types of treatment include external beam proton therapy, transpupillary thermotherapy, surgical resection techniques (transretinal endoresection and trans-scleral partial choroidectomy), gamma knife stereotactic surgery and also combination of these modalities. For small size tumors, the treatment available includes photocoagulation, photodynamic therapy, and local resection. The selection of appropriate treatment largely depends on the size and location of the tumor; associated ocular findings; the status of the fellow eye; and individual factors, including age, life expectancy, quality of life issues, concurrent systemic diseases and patient expectations.
Diagnosis of uveal melanoma consists of careful examination of the eye by an experienced clinician. Clinical manifestations include tumor thickness more than 2 mm, sub retinal fluid, and orange pigment on the tumor surface. Various ancillary diagnostic tests include ultrasonography, high resolution ultrasound biomicroscopy, indocyanine green angiography, fluorescein angiography and oclular coherence tomography. Eye exams include ophthalmoscopy, slit-lamp biomicrocopy and gonioscopy. Eye examination is carried out by dilation of pupil with the help of medicated drops allowing doctors to visualize the parts of eye clearly through lens. Biopsy is a rarely used diagnostic test for intraocular melanoma. Regular eye examinations by an ophthalmologist are the best way to find uveal melanoma early, when chances for successful treatment are the highest.
Global Uveal Melanom Market: Trends
The treatment for such metastasis disease is continuously demanding more research to determine the most effective, and life saving treatments. Extensive research is being carried out in areas of immunotherapy and targeted therapy. Ipilimumab is one such example of immunotherapy shown to help people with advanced melanoma to boost the overall immunity; however its benefits are still under clinical trials for eye melanoma. Other similar drugs under investigation include nivolumab and lambrolizumab. Selumetinib is an example of targeted drug known to slow down the growth of eye melanoma. Other targeted drugs under investigation include vemurafenib, dabrafenib and trametinib amongst various others. Astra Zeneca plc, Eli Lilly & Co., Pfizer, Inc. Novartis AG, and Spectrum Pharmaceuticals, Inc., are few key players contributing to the global uveal melanoma market.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
2. Insights and Tools
The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.
3. Actionable Results
The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.