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Global G-Protein Coupled Receptors (GPCRs) Market: Urgent Need for Drug Discovery Impels Usage of GPCR Assays, Says TMR

Posted on Oct 18, 2016

The key players operating in the global G-protein coupled receptors (GPCRs) market are Thermo Fisher Scientific, Inc., EMD (Merck) Millipore, Becton, Dickinson and Company, PerkinElmer, Inc., and Sigma-Aldrich Corporation. These players raked in a dominant share of 98.1% in the global market in 2013. The dominance of these companies was defined by persistence to develop innovative and technologically advanced products. “However, to remain relevant in the high competitive market manufacturers must focus on product differentiation,” states the lead author of this research report. Existing players will face tough competition from new entrants as they are projected to offer improved drug discovery procedures and assay products to the wide base of consumers. 

Oncology Emerges as the Predominant User of GPCR Assays

According to the research report, the global GPCRs market is expected to be worth US$3.53 bn by 2022 from US$1.63 bn in 2013. Analysts predict that the global market is expected to surge at a CAGR of 8.8% between the forecast years of 2014 and 2022. Analysts predict that GPCRs will be predominantly used in developing in the oncology sector due to a high prevalence of cancer across the globe. Owing to this reason, the oncology therapeutic area segment is expected to progress at a CAGR of 9.4% during the forecast period. Asia Pacific is expected to an emerging GPCRs market in the coming years. Untapped opportunities and rising investment in healthcare infrastructure are expected to expand this regional market at a CAGR of 12.5% during the forecast period. 

Advantages of GPCR Assays Favors Market Growth

The high prevalence several disorders and diseases pertaining to cardiovascular, nervous system, immune system, genitourinary, and cancer have created a massive demand for drug discovery to find solutions. This has translated into a burgeoning demand for GPCR assays as they bring in specificity and sensitivity in the development advanced therapeutics. The advantages of GPCR assays over traditional assays, such as their ability to offer improved in vivo environment for conducting biochemical studies is favoring the growth of the global market. Additionally, they are also designed to help researchers measure every molecular or cellular functioning in the human body. Thus, GPCR assays have become increasingly popular amongst pharmaceutical companies and life sciences industry players. 

The World Health Organization (WHO) predicted that there will be a 70% rise in the number of people suffering from cancer in the coming two decades. This alarming statistic clearly spells an opportunity for the GPCR vendors in the market as the healthcare industry, on the whole, will work towards drug development in the near future. Currently, cardiovascular diseases account for a significant number of deaths across the globe. Thus, development of therapies to treat the conditions pertaining to the cardiovascular system will augur well for the growth of the global market. 

The increasing number of government initiatives are also making a positive contribution to the global market. The significant interest of governments and the investments they’ve made so far have all contributed toward technologically advanced products and output-driven research and development activities. 

High Cost of Equipment to Strain Uptake of Assays

On the other hand, the global GPCR market is likely to be hampered by the exceptionally high cost of maintaining cell lines. The market will also feel the strain of costly equipment and instruments that are required in for conducting GPCR-based processes. The overall cost required to sustain the usage of GPCR assays is projected to create a negative impact on the growth of the market, especially in the developing regions that are marred by low-income groups. 

The review is based on Transparency Market Research’s report, titled “G-Protein Coupled Receptors (GPCRs) Market  - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014-2022.” 

The global GPCRs market is segmented as follows: 

GPCRs Market, by Assay Type

  • Calcium Level Detection Assays 
  • GTPγS Binding Assays 
  • cGMP Assays
  • Reporter Gene Assays 
  • Receptor Internalization Assay 
  • cAMP Assays  

GPCRs Market, by Therapeutic Area

  • Cardiovascular System
  • Central Nervous System
  • Respiratory System
  • Immune System
  • Reproductive System
  • Oncology
  • Others 

GPCRs Market, by Geography

  • North America
  • U.S.
  • Canada 

Europe

  • U.K.
  • Germany
  • France
  • Rest of Europe 

Asia Pacific

  • China
  • Japan
  • India
  • Rest of Asia Pacific 

Rest of the World (RoW)

  • Latin America
  • Middle East
  • Africa

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