Nano Antibodies Market Introduction
Nano antibodies are a novel class of proprietary therapeutic proteins based on single-domain antibody fragments that contain unique structural and functional properties of naturally-occurring heavy chain only antibodies. Nano antibodies, also known as nAb, are single-domain VHH antibodies derived from Camelidae. Compared to conventional monoclonal and polyclonal antibodies, nAbs has few advantages such as small size, high affinity, and unsurpassed stability. Nano antibodies enable rapid generation and large-scale production of novel biological therapeutics that have potential in a range of human diseases. The technology is used to develop heavy-chain antibodies that contain single variable domain (VHH) and two constant domains (CH2, CH3). Due to small size and unique structure, nano antibodies act as ideal building blocks for generation of biological drugs.
Global Nano Antibodies Market - Competitive Landscape
The VHH antibody has higher probability to adopt identical intra and extracellular folding. Hence, nano antibodies are used for intracellular probing. Moreover, high stability and suprmolecular assembly of antibody makes it an ideal alternative to monoclonal or polyclonal antibodies. Hence, companies are investing on more research and development for product development and approval process in different regions.
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Ablynx, a Sanofi company, is engaged in the development of nano antibodies, a proprietary therapeutic protein based on single-domain antibody fragments, which combine the advantages of conventional antibody drugs with some of the features of small-molecule drugs. Nano antibodies are used in the treatment of a range of serious and life-threatening human diseases. Ablynx advances a portfolio of nano antibodies based therapeutic programs in several major disease areas such as inflammation, hematology, immuno-oncology, and oncology.
Alphamab Co. Ltd.
Alphamab Co. Ltd. was established in early 2009 by Dr. Ting Xu. The company has strategic alliances with the Shanghai Institute of Materia Medica, the Chinese Academy of Science, the Southeast University, and Thermo Scientific as part of its open drug discovery platform. Currently, Alphamab has more than 30 active projects, including biosimilars, novel mAbs & engineered version of mAbs, and proteins.
Global Nano Antibodies Market Dynamics
High Prevalence of Chronic Diseases Drives Demand for Nano Antibodies
The global nano antibodies market is driven primarily by high prevalence of chronic diseases such as cancer, rare blood disorders, and diabetes. Increase in incidence of inflammation among the geriatric population due to infection and surgery and rise in hematology related disorders, especially among the young population due to increase in blood transfusion during surgery or trauma, are the other factors projected to propel the global nano antibodies market.
Owing to the increasing problem of cancer disease & diagnostic procedures, nano antibodies are finding wide application to be used among the practitioners and non-specialists for practice and surgery. Moreover, in the past few years, nano antibodies have been extensively used in oncology and hematology procedures for the treatment of life-threatening diseases.
Manufacturers Focus on Innovative Techniques to Enter Developing Nano Antibodies Market
Manufacturers in the global nano antibodies market are increasingly investing in research & development to find new and innovative techniques to develop modified nano antibodies. These also focus on offering highly-efficient and reliable nano antibodies to provide better protection against binding of antibody to antigen associated with cancer or other infectious diseases.
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The global nano antibodies market is highly fragmented, with the presence of small number of manufacturers, especially in the developing countries. Emergence of new technologies for delivering the antibodies and high protective structure compared to monoclonal & polyclonal antibodies are factors anticipated to augment the global market. Moreover, with increasing number of joint partnership research, product differentiation has become vital to gain competitive edge in the global nano antibodies market.
Inherent Immunogenicity of Nano Antibodies likely to Restrain Market
One of the key factors hampering the growth of the global nano antibodies market is the inherent immunogenicity of the foreign protein toxin. However, in response to the growing demand for nano antibodies by consumers, companies are focusing on developing new nano antibodies with low capacitance to provide protection against diseases. Moreover, single use of nano antibodies reproduces tumor growth in few cases which is expected to restrain the global market during forecast period.
Global Nano Antibodies Market Segmentation
In terms of type, the global nano antibodies market can be classified into:
- Monovalent Nano Antibody
- Multivalent Nano Antibody
- Fusion Nano Antibody
Based on application, the global nano antibodies market can be categorized into:
- Live Cell Imaging
- Fluorescent Protein Enhancement
In terms of end-user, the global nano antibodies market can be divided into:
- Research Laboratories & Clinics
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
2. Insights and Tools
The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.
3. Actionable Results
The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.