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Muckle-Wells Syndrome Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2016 - 2024

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Muckle-Wells Syndrome Market: Overview

Muckle-Wells syndrome (MWS) refers to a rare inherited autoinflammatory disease, of the cryopyrin associated periodic syndromes (CAPS), caused by mutations in the NLRP3/ CIAS1 gene. The gene is associated with the coding of the protein cryopyrin. Mutations in the gene are said to result in the increased activity of a protein known as interleukin (IL) 1ß, which leads to inflammatory symptoms such as joint pain and fever. The syndrome is characterized by recurrent episodes of rashes, acute attacks of fever, conjunctivitis, and painful joint. In most cases, the syndrome also leads to progressive sensorineural hearing loss. Renal failure are also often associated in untreated conditions owing to the abnormal accumulation of the protein amyloid in the kidneys.

This report examines the market concerned with the diagnosis and treatment of MWS and presents a thorough overview of the present state of diagnostic tools and techniques and various drug compounds presently marketed for MWS. The report also includes detailed data regarding the state of ongoing research and development in the field, drugs in clinical trials and pipeline, and scope of growth for companies wanting to foray into the market.

Muckle-Wells Syndrome Market: Scope of the Report

The report presents an exhaustive account of the factors that are expected to have a sizeable impact on the market’s future growth prospects. As such, key growth drivers, challenges, trends of past and the present, regulatory factors, and recent developments across the market’s regulatory landscape are analyzed in the report.

The report also presents a detailed overview of the competitive landscape of the global MWS market. In this section, details regarding companies in the market through already marketed drugs or drugs in pipelines are examined. Details such as market shares, SWOT analysis, product portfolios, finances (where available) and geographical presence are included.

Muckle-Wells Syndrome Market: Drivers and Restraints

The market is expected to grow over the forecast period owing to advances in genetic engineering and increased focus of international pharmaceutical companies on research and development in the field of rare diseases such as MWS. Since MWS is a newly discovered condition, data regarding the actual prevalence and incidence are somewhat difficult to determine.

Also, there is a vast lack of awareness regarding the disease and R&D costs are high. These factors are expected to arrest the growth of the global MWS market to a large extent in the next few years. Nevertheless, government intervention, funds from private and public bodies, and attempts to raise awareness among the masses about the diseases could help the market gain traction.

Muckle-Wells Syndrome Market: Available Diagnostic and Therapeutics Options

As such, not many drug candidates are available to treat the condition completely. The few treatment options available in the market include Arcalyst (Rilonacept), an interleukin-1 blocker, by Regeneron Pharmaceuticals, Ilaris (Canakinumab), a monoclonal antibody to interleukin-1 beta, by Novartis Pharmaceuticals, and Kineret (Anakinra), an IL-1 receptor antagonist, by Biovitrum pharmaceuticals. Many drug candidates are also in pipelines.

For correcting the hearing loss that most MWS patients develop, hearing aids are prescribed. For alleviating joint pain, non-steroidal anti-inflammatory drugs are prescribed. The use of corticosteroids in high doses has also demonstrated positive effect in certain cases, but this may lead to several long- and short-term side effects.

For diagnosis of MWS, a thorough evaluation of the patient’s syndromes is done. For confirmation of the diagnosis, identification of NLRP3/ CIAS1 gene mutation is done. Identification of mutation is, however, not a sure shot way of confirming the diagnosis of MWS as not all patient possess this mutation.

Muckle-Wells Syndrome Market: Competitive Landscape

The vendor landscape of the global MWS market features few players and a low level of competition, typical of most new markets. More companies are expected to enter the market via experimental drugs in the next few years. Better diagnostic methods are expected to be devised owing to increased vendor base in the market and advances in genetic engineering. Some of the key vendors presently operating in the market are Novartis AG, Charite University, Berlin, Germany, Istituto Giannina Gaslini, and Regeneron Pharmaceuticals, Inc.

Major regions analyzed under this research report are:

  • Europe
  • North America
  • Asia Pacific
  • Rest of the World

This report gives you access to decisive data such as:

  • Market growth drivers
  • Factors limiting market growth
  • Current market trends
  • Market structure
  • Market projections for the coming years

Key highlights of this report

  • Overview of key market forces propelling and restraining market growth
  • Up-to-date analyses of market trends and technological improvements
  • Pin-point analyses of market competition dynamics to offer you a competitive edge
  • An analysis of strategies of major competitors
  • An array of graphics and SWOT analysis of major industry segments
  • Detailed analyses of industry trends
  • A well-defined technological growth map with an impact-analysis
  • Offers a clear understanding of the competitive landscape and key product segments

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

The study is a source of reliable data on:

  • Market segments and sub-segments
  • Market trends and dynamics
  • Supply and demand
  • Market size
  • Current trends/opportunities/challenges
  • Competitive landscape
  • Technological breakthroughs
  • Value chain and stakeholder analysis

The regional analysis covers:

  • North America (U.S. and Canada)
  • Latin America (Mexico, Brazil, Peru, Chile, and others)
  • Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
  • Eastern Europe (Poland and Russia)
  • Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
  • Middle East and Africa (GCC, Southern Africa, and North Africa)

The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.

A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.

Highlights of the report:

  • A complete backdrop analysis, which includes an assessment of the parent market
  • Important changes in market dynamics
  • Market segmentation up to the second or third level
  • Historical, current, and projected size of the market from the standpoint of both value and volume
  • Reporting and evaluation of recent industry developments
  • Market shares and strategies of key players
  • Emerging niche segments and regional markets
  • An objective assessment of the trajectory of the market
  • Recommendations to companies for strengthening their foothold in the market  

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

Note : All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Transparency Market Research.

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