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Protein expression, purification and large scale production is achieved by manipulation in the gene expression process of an organism such that it is able to express large amounts of a recombinant gene. It is not a trivial task and faces a huge competition in the market because of the fragmented scenario over the globe. Fermenters and bioreactors with different expression system capabilities, purity options, quality control and the production timeline differentiate various services available in the market. Various organizations have developed their own in-house methods of production and purification. Bacterial and yeast systems are mostly used in case of microbial protein production process because of simple physiology, short generation times and high yield of product, both having their own advantages and disadvantages. Among bacterial, E. coli has been most widely used for recombinant protein expression and production. Clients can use the service for the manufacture of either the regular proteins whose gene sequence is available in the public domain or can manufacture its customized gene expression

Producing recombinant proteins is often the limiting and most expensive step in life science research. Expression yield of recombinant proteins vary by orders of magnitudes from protein to protein reflecting the difference in the cost of production process. These services are more preferred due to the increasing customization in the genetic sequences. Microbial protein production services also involves the use of various types of tags for purification purposes such as FLAG-tag, His-tag, Fc-fusion tag, GST-tag, Myc-tag, HA-tag, MBP-tag and others.

Microbial Protein Production Services Market: Drivers & Restraints

Increase in the number of applications of microbial proteins such as the increasing enzymatic applications and their requirement in various industries, increase in the production of bio-pharmaceuticals like monoclonal antibodies, hepatitis B vaccine and HPV vaccine are increasing the need of microbial protein production services to meet the demand. Recent advances in proteomics and rapid growth in protein drug market also constantly increasing the market of pure and active proteins. Increasing number of CROs also fuels the services market. One of the limiting factor for the growth is not possessing the same capability as eukaryotic cells for protein glycosylation and other post-translational modifications and thus limits its applications. Increasing regulatory pressure on CROs, high cost involved, lack of skilled manpopwer, infrastructure and skilled expertise may also restricts the growth.

Microbial Protein Production Services Market: Segmentation 

By Production Type:

  • Bacterial Protein Expression
  • Yeast Protein Expression
  • Other microbial protein expression

By Service Type:

  • Customized Production
  • Regular Production

By End User:

  • Pharmaceutical Industry
  • Biotechnology Companies
  • Food and Feed Industry
  • Research Organizations
  • Academic Institutes

By Geography

  • North America
  • Europe
  • Latin America
  • Asia-Pacific
  • Middle East and Africa

Microbial protein production services constitutes of companies and research organizations engaged in protein production and purification services. Bio therapeutic protein and vaccine manufacturers faces various challenges related to time and cost in the drug discovery and development process. The service units take only the protein sequence and adjust the amount and purity required for protein production. These type of services help in saving time and cost to accomplish the research needs. Competitive prices of different products and the quality differentiates the market players. Continuous innovations and improvements in the protein expression systems are the need of the market. Various mergers and partnership deals in this sector also fuels the market such as Ewos recently offered a US $30 million funding package to Calysta which is planning to manufacture novel high quality microbial proteins for the fish feed industry in the UK.

A geographic condition regarding the Microbial Protein Production Services Market, it has been segmented into five key regions: North America, Latin America, Europe, Asia-Pacific and the Middle East & Africa. With large number of research organizations and usage in number of applications in various industries, North America depicts an established market for these services. Extensive competition is faced by the European countries because of the excellent number of contract research organizations and established network of universities and research institutions in the region. Asia Pacific is the growing market because of establishment of more biotechnological and pharmaceutical industries and opening of more contract research organizations. Moreover, low cost manufacturing also attracts the market in this region.

Some of the market players in the microbial protein production service market includes Wacker, Chemie AG, Icosagen, Sino Biological, GenScript, LP3 Labs, Lonza, Biomatik, GenWay Biotech, Inc., Olympic Protein Technologies, Amid Biosciences and many others.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Microbial Protein Production Services Market

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