Live attenuated vaccines are prepared by weakening the bacterial or viral strains using stable mutations. This technology does not kill the microorganism. It removes the disease causing ability of the microorganism. The live attenuated vaccine elicits the immune system in a vaccinated individual. Live attenuated vaccines are used to prevent diseases such as tuberculosis, yellow fever, retroviral, measles, polio, and others. Initiatives by governments of various countries has significantly decreased the number of polio cases across the world. According to the World Health Organization (WHO), since 1988, polio cases have decreased by over 99%. In 2016, only 37 cases were reported as compared to 350,000 in 1988. Over 16 million people have been saved from paralysis attack due to polio. Failure of completely eradicate polio is likely to result in more than 200,000 new cases within 10 years.
Live attenuation technology is most widely used for vaccine preparation. This factor drives the global live attenuated vaccines market. Properties of live attenuated vaccines such as oral administration, low cost of production, prevention by pathogen, long-lasting, and high effectiveness drive the market. Tuberculosis is one of the top ten causes of death globally. According to the World Health Organization, in 2015, tuberculosis accounted for 1.8 million deaths and 10.4 million people were living with the disease. Over 95% deaths due to tuberculosis were in middle- or low-income countries. In 2015, an estimated 170,000 children died and 1 million children were ill with tuberculosis. Regulatory hurdles, genetic stability, and environmental risks are likely to restrain the live attenuated vaccine market.
The global live attenuated vaccines market can be categorized based on product type, age group, end-user, and region. In terms of product type, the market can be divided into viral and bacterial. The viral segment can be further classified into oral polio vaccine (OPV), Vaccinia (smallpox) vaccine, adenovirus oral vaccine (military), yellow fever vaccine, shingles vaccine, varicella (chickenpox) vaccine, influenza vaccine (nasal spray) flumist, rotavirus vaccine, and MMR vaccine. The bacterial segment can be further divided into live cholera vaccine, typhoid oral vaccine, and BCG (tuberculosis) vaccine. Based on age group, the market can be categorized into geriatrics, adults, adolescents, and pediatrics. In terms of end-user, the market can be classified into hospital pharmacies and drug stores.
Geographically, the global live attenuated vaccines market can be segmented into Asia Pacific, Latin America, Europe, North America, and Middle East & Africa. According to the World Health Organization (WHO), measles is one of the major causes of death among young children globally; every hour about 15 deaths occur, each day approximately 367 deaths. The disease accounted for 134 200 deaths in 2015. Asia Pacific is anticipated to capture major market share owing to high prevalence of tuberculosis. According to the WHO, India has large number of tuberculosis patients, 60% of the world’s tuberculosis patients are from Asia Pacific, especially from emerging countries such as Pakistan, Indonesia, and China. The market in Middle East & Africa is anticipated to grow during the forecast period owing to increasing number of deaths due to yellow fever. According to the World Health Organization, 32 countries in Africa are at high risk of yellow fever. Hence, demand for live attenuated vaccines is high in the region.
Key players operating in the global live attenuated vaccines market are Serum Institute of India Pvt. Ltd., Merck Sharp & Dohme Corp. (a subsidiary of Merck & Co., Inc.), BioDiem, GlaxoSmithKline plc, Vivaldi Biosciences, Inc., and Codagenix, Inc., among others.
This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.
Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:
- Customer Experience Maps
- Insights and Tools based on data-driven research
- Actionable Results to meet all the business priorities
- Strategic Frameworks to boost the growth journey
The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.
The following regional segments are covered comprehensively:
- North America
- Asia Pacific
- Latin America
- The Middle East and Africa
The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.
Below is a snapshot of these quadrants.
1. Customer Experience Map
The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.
2. Insights and Tools
The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.
3. Actionable Results
The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.
4. Strategic Frameworks
The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.
The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:
1. What can be the best investment choices for venturing into new product and service lines?
2. What value propositions should businesses aim at while making new research and development funding?
3. Which regulations will be most helpful for stakeholders to boost their supply chain network?
4. Which regions might see the demand maturing in certain segments in near future?
5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?
6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?
7. Which government regulations might challenge the status of key regional markets?
8. How will the emerging political and economic scenario affect opportunities in key growth areas?
9. What are some of the value-grab opportunities in various segments?
10. What will be the barrier to entry for new players in the market?
Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.