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Leishmaniasis is a disease caused by the Leishmania parasites. The Leishmania parasite is a single cell protozoan, which is transmitted by the bite of the female phlebotomine sand fly infected by the parasite. There are over 20 Leishmania species reported, which are transmitted to humans by the bite of infected female phlebotomine sandflies. Furthermore, over 90 sand-fly species are known to transmit Leishmania parasites. Leishmaniasis consists of three different forms: visceral Leishmaniasis, cutaneous Leishmaniasis, and mucocutaneous Leishmaniasis. The visceral form of Leishmaniasis is also known as ‘Kala-azar’. Cutaneous Leishmaniasis is the most common form of Leishmaniasis.

Leishmaniasis primarily occurs due to poor hygienic conditions and thus, affects the poorest of people in the community who are facing problems such as poor housing, malnutrition, and weak immune systems. The disease is also linked to environmental changes such building of dams, irrigation schemes, deforestation, urbanization, etc. Each year, around 1.6 million new infections occur, and 47,000 deaths occur due to Leishmaniasis. 

In 95% of cases of visceral leishmaniasis (VL), the disease can be fatal if left untreated. The clinical symptoms of VL include weight loss, irregular bouts of fever, liver and spleen enlargement, and anemia. This form of Leishmaniasis is highly endemic in the Indian subcontinent and in East Africa. Cutaneous Leishmaniasis (CL) is the most common form of Leishmaniasis. It is characterized by ulcers and skin lesions on the body. This results in marks and scars on the patient’s body, which may last a lifetime and cause certain disabilities. Mucocutaneous Leishmaniasis can cause partial or total damage to the mucous lining of the mouth, nose, and throat. Persons infected with HIV have a greater risk of acquiring Leishmaniasis due to their compromised immune systems.

Globally, Africa, North America, and south East Asia are witnessing major problems due to lack of medication available to treat Leishmaniasis. High cost of the drugs restricts Leishmaniasis treatment in many endemic regions. High priority was not provided for leishmaniasis drug development programs by pharmaceutical companies, as the disease primarily affects the poor from developing nations and hence, are not able to get good returns on their research and development cost. However, increasing awareness about the disease and rise in incidence rate of the disease in other parts of the globe. Moreover, the unmet medical need is estimated to present an opportunity for all research and development programs to invest in the global leishmaniasis drugs market. Currently, no vaccination is available for the treatment of this disease, and the focus relies on chemotherapy and prevention and control measures of leishmaniasis.

The global market for leishmaniasis treatment can be segmented on the basis of type of drug used for its treatment, diagnostic method, and vector control methods. In terms of type of drug used, the market can be segmented into pentavalent antimonials like Sodium stibogluconate, SSG Meglumine antimoniate; antibiotics like  Amphotericin B, Liposomal amphotericin B, Miltefosine, Paromomycin and Pentamidine. Market segmentation based on diagnostic methods include rapid test for detection of the parasite or antibodies against it like- rK39 Dipstick, Direct Agglutination Test (DAT), Kala-azar Latex Agglutination Test (KAtex), and culture and polymerase chain reaction. Market segmentation by vector control methods include use of nets or mesh, use of sprays and insecticides effective against sandflies. Pharmaceutical companies and organizations are likely to adopt new methods and treatments due to continuous research and development in scientific technology to cure this disease. This, in turn, is likely to drive the demand for leishmaniasis treatment drugs during the forecast period.

Key players operating in the leishmaniasis treatment market include Enzon Pharmaceuticals (Abelcet), Paladin Therapeutics Inc., Gland Pharma/iOWH, Sequus Pharmaceuticals, Lifecare Innovation, and Sanofi Aventis .

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Leishmaniasis Treatment Market