Industry Verticals »

All Categories

Insights »

About TMR »

In Vitro Toxicity Testing Market

In Vitro Toxicity Testing Market - Global Industry Size, Share, Trends, Analysis And Forecast 2012 - 2018

Several changes are taking place in the pharmaceutical industry, in order to improve efficiency and reduce cost, besides several drug developments and testing. High rate of attrition in drug development in the last two decades, especially when the drug reaches the later stages of development, is a major concern for the pharmaceutical industry. As a result, the heavy cost on research and development is incurred exceedingly on the pharmaceutical company. Thus, the pharmaceutical industry is constantly in the need of finding reasons for attrition failures.
 
However, the adoption of in vitro ADME screening into drug discovery programs have reduced this drug failure up to an extent. In 1991, 40% of clinical trial failures were due to poor pharmacokinetics. By, 2000 this number was reduced to 10% and this happened with the advent of in vitro ADME. In vitro ADME has been widely accepted in the pharmaceutical industry and its value has been recognized in the last five years. Some new cellular models and techniques have expanded the market of in vitro toxicology and this market is expected to grow a CAGR of 15.3% from 2013 to 2018. The later stage attrition can be overcome by the advent and subsequent growth of the in vitro toxicology testing methods.
 
There are several advantages of the in vitro toxicology approach as it has improved the overall predictive quality because human cells are being used. Moreover, this method is cost effective and is less time consuming as compared to the animal testing methods. Earlier, the methods for predicting toxicity in humans were same for testing toxicity in animals, but there are many chemicals that are toxic to one and non toxic to another and vice versa. It creates a lot more confusion in the testing and development of new drugs. Thus, the testing that is been conducted on human cells gives better opportunity to understand and improve the predictions of toxicity in humans. Thus, these in vitro toxicology methods are likely to gain more importance in the forecasted period with the continuous advancements in technology.
 
Although the in vitro toxicity market is new, it has huge potential in the future. Technological development and new product launch in this field will play a major role in this industry. However, the absence of pharmaceutical giants in this sector provides better opportunity for the new entrants to establish themselves in the market. Therefore, the company ready to invest can enter this emerging market and is likely to be successful as the market offers high potential to the new players.
 
In the present scenario, in vitro methods are widely used in by all regulatory bodies and industries in safety assessment, risk evaluation and toxicity testing. The main idea behind using in vitro techniques over animal testing are the advantages associated with them. The in vitro method is mainly used to elucidate mechanisms of toxicity in a drug and its effect on the cell or tissue. The development of Ames Mutagenic Assay made the non-animal testing more popular as compared to animal testing.
 
Furthermore, the regulatory concerns and political barriers are further expected to boost this market. Ethical concerns related to animals are one of the key factors in many countries that are likely to drive this market. The regulations are strict for animal testing in the countries such as Europe and the companies operating in this region are bound to ignore and move away from animal testing and choose in vitro toxicology testing for several product developments and research areas. Similarly, other emerging nations of Asia are also expected to follow suit and thus lead to better and rapid growth of in vitro testing methods in these regions.  Also, better economic conditions in this region will be highly supporting in adoption of this new technology and thus new developments in the pharmaceutical, chemicals, cosmetics and food industries will emerge rapidly in the future.
    TABLE OF CONTENTS
     
    CHAPTER 1 PREFACE
    1.1 REPORT DESCRIPTION
    1.2 RESEARCH METHODOLOGY
     
    CHAPTER 2 EXECUTIVE SUMMARY
     
    CHAPTER 3 IN VITRO TOXICITY TESTING MARKET OVERVIEW
    3.1 MARKET TRENDS AND FUTURE OUTLOOK
    3.2 GLOBAL IN VITRO TOXICITY TESTING MARKET SIZE, 2011 – 2018 (USD MILLION) 
    3.3 MARKET DYNAMICS
          3.3.1 DRIVERS
                  3.3.1.1 Opposition to Animal Testing
                  3.3.1.2 Advancement in Toxicity Testing Procedure
                  3.3.1.3 Strict Regulations from the Government of Different Countries
         3.3.2 RESTRAINTS
                  3.3.2.1 Questionable Predictive Power
          3.3.3 OPPORTUNITIES
                  3.3.3.1 Future Technological and Scientific  Innovations
     
    CHAPTER 4 MARKET SEGMENTATION
    4.1 IN VITRO TESTING MARKET BY END USE
          4.1.1 COSMETICS AND HOUSEHOLD PRODUCTS
          4.1.2 PHARMACEUTICAL INDUSTRY
          4.1.3 FOOD INDUSTRY
          4.1.4 CHEMICALS INDUSTRY
    4.2 IN VITRO MARKET SEGMENTATION BY APPLICATION
          4.2.1 IN VITRO TOXICITY TESTING METHODS
          4.2.2 CYTOTOXICITY ESSAYS USED FOR IN VITRO TOXICITY TESTING
    4.3 IN VITRO TOXICITY TESTING MARKET SEGMENTATION BY TYPE
          4.3.1 BY ABSORPTION
                  4.3.1.1 Distribution
                  4.3.1.2 Metabolism
                  4.3.1.3 Excretion
         4.3.2 BY DOSE
                 4.3.2.1 Dose Response
                 4.3.2.2 Threshold Response
         4.3.3 BY TOXIC SUBSTANCES
                 4.3.3.1 Toxicant
                 4.3.3.2 Toxin
                 4.3.3.3 Acute and Chronic Toxicity
                 4.3.3.4 Toxicokinetics
    4.4 MARKET SEGMENTATION BY GEOGRAPHY
          4.4.1 NORTH AMERICA
          4.4.2 EUROPE
                 4.4.2.1 SWITZERLAND
         4.4.3 ASIA
         4.4.4 REST OF THE WORLD
     
    CHAPTER 5 COMPETITIVE LANDSCAPE
    5.1 MARKET SHARE BY KEY PLAYERS
     
    CHAPTER 6 RECOMMENDATIONS
    6.1 MARKET STRATEGY FOR SUCCESS
    6.2 BARRIERS TO BE CONSIDERED
     
    CHAPTER 7 COMPANY PROFILES
    7.1 BIO-RAD LABORATORIES
          7.1.1 COMPANY OVERVIEW
          7.1.2 FINANCIAL PERFORMANCE
          7.1.3 PRODUCT PORTFOLIO
          7.1.4 BUSINESS STRATEGIES
          7.1.5 RECENT DEVELOPMENTS
    7.2 CYPROTEX
          7.2.1 COMPANY OVERVIEW
          7.2.2 BUSINESS OVERVIEW
          7.2.3 FINANCIAL OVERVIEW
          7.2.4 RECENT DEVELOPMENTS
    7.3 ACCELRYS INC 
          7.3.1 COMPANY OVERVIEW
          7.3.2 BUSINESS OVERVIEW
          7.3.3 FINANCIAL OVERVIEW
          7.3.4 RECENT DEVELOPMENTS
    7.4 CHARLES RIVER LABORATORIES INTERNATIONAL INC. 
          7.4.1 COMPANY OVERVIEW
          7.4.2 FINANCIAL OVERVIEW
          7.4.3 PRODUCT PORTFOLIO
          7.4.4 BUSINESS OVERVIEW
          7.4.5 RECENT DEVELOPMENTS
    7.5 COVANCE INC. 
          7.5.1 COMPANY OVERVIEW
          7.5.2 FINANCIAL OVERVIEW
          7.5.3 BUSINESS STRATEGIES
          7.5.4 RECENT DEVELOPMENTS
    LIST OF TABLES
     
    TABLE 1 DRIVERS OF GLOBAL IN VITRO TOXICITY TESTING  MARKET: IMPACT ANALYSIS 
    TABLE 2 RESTRAINTS FOR IN VITRO TOXICITY TESTING MARKET: IMPACT ANALYSIS 
    TABLE 3 GLOBAL IN VITRO TESTING MARKET BY END USE, 2012 – 2018 (USD MILLION) 
    TABLE 4 GLOBAL IN VITRO TOXICITY TESTING MARKET BY TYPE, 2012 – 2018 (USD MILLION) 
    TABLE 5 GLOBAL IN VITRO TOXICOLOGY TESTING MARKET BY GEOGRAPHY, 2010-2018, (USD MILLION) 
    TABLE 6 GLOBAL IVTT COSMETICS AND HOUSEHOLD PRODUCTS BY GEOGRAPHY, 2010-2018, (USD MILLION) 
    TABLE 7 GLOBAL IVTT PHARMACEUTICAL INDUSTRY MARKET BY GEOGRAPHY, 2010-2018, (USD MILLION) 
    TABLE 8 GLOBAL IVTT FOOD INDUSTRY MARKET BY GEOGRAPHY, 2010-2018, (USD MILLION) 
    TABLE 9 GLOBAL IVTT CHEMICALS INDUSTRY MARKET BY GEOGRAPHY, 2010-2018, (USD MILLION) 
    TABLE 10 NORTH AMERICA IVTT MARKET, BY END USE, 2010-2018, (USD MILLION) 
    TABLE 11 NORTH AMERICA IVTT MARKET, BY TYPES, 2010-2018, (USD MILLION) 
    TABLE 12 EUROPE IVTT MARKET, BY END USE, 2010-2018, (USD MILLION) 
    TABLE 13 EUROPE IVTT MARKET, BY TYPES, 2010-2018, (USD MILLION) 
    TABLE 14 SWITZERLAND IVTT MARKET, BY END USE, 2010-2018, (USD MILLION) 
    TABLE 15 SWITZERLAND IVTT MARKET, BY TYPE, 2010-2018, (USD MILLION) 
    TABLE 16 ASIA IVTT MARKET, BY END USE, 2010-2018, (USD MILLION) 
    TABLE 17 ASIA IVTT MARKET, BY TYPES, 2010 – 2018 (USD MILLION) 
    TABLE 18 ROW IVTT MARKET, BY END USE, 2010-2018, (USD MILLION) 
    TABLE 19 ROW IVTT MARKET, BY TYPES, 2010-2018, (USD MILLION) 
    TABLE 20 MARKET POSITIONING OF MAJOR IN VITRO TOXICITY TESTING MARKET PLAYERS, BY COUNTRY 

    LIST OF FIGURES

     

    FIG. 1 IN VITRO TOXICITY TESTING MARKET ESTIMATES AND FORECAST, 2012 – 2018 (USD MILLION) 

    FIG. 2 IN VITRO TOXICITY TESTING MARKET BUBBLE CHART GEOGRAPHY RANKING, 2011 (USD MILLION) 

    FIG. 3 IN VITRO TOXICITY TESTING MARKET BUBBLE CHART GEOGRAPHY RANKING, 2018 (USD MILLION) 

    FIG. 4 GLOBAL IN VITRO TOXICITY MARKET ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 5 GLOBAL IN VITRO TOXICITY MARKET BY END USE ETIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 6 GLOBAL IN VITRO TOXICITY COSMETICS AND HOUSEHOLD PRODUCTS MARKET ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 7 GLOBAL IN VITRO TOXICITY PHARMACEUTICAL PRODUCTS MARKET ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 8 GLOBAL IN VITRO TOXICITY FOOD PRODUCTS MARKET ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 9 GLOBAL IN VITRO TOXICITY CHEMICALS MARKET ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 10 GLOBAL IN VITRO TOXICITY MARKET BY TYPE ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 11 GLOBAL IN VITRO TOXICITY MARKET BY ABSORPTION ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 12 GLOBAL IN VITRO TOXICITY MARKET BY DOSE ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 13 GLOBAL IN VITRO TOXICITY MARKET BY TOXIC SUBSTANCES ETIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 14 GLOBAL IN VITRO TOXICITY MARKET BY ABSORPTION ESTIMATES AND FORECAST, BY GEOGRAPHY, 2011 – 2018 (USD MILLION) 

    FIG. 15 GLOBAL IN VITRO TOXICITY MARKET BY TOXIC SUBSTANCES ESTIMATES AND FORECAST, BY GEOGRAPHY, 2011 – 2018 (USD MILLION) 

    FIG. 16 GLOBAL IN VITRO TOXICITY MARKET BY DOSE ESTIMATES AND FORECAST, BY GEOGRAPHY, 2011 – 2018 (USD MILLION) 

    FIG. 17 SWITZERLAND IN VITRO TOXICITY MARKET BY END USE ESTIMATES AND FORECAST, 2011 – 2018 (USD MILLION) 

    FIG. 18 SWITZERLAND IN VITRO TOXICITY MARKET BY TYPE ESTIMATES AND FORECAST,  2011 – 2018 (USD MILLION) 

Copyright © Transparency Market Research, Inc. All Rights reserved

In Vitro Toxicity Testing Market

Schedule a Call