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Several changes are taking place in the pharmaceutical industry, in order to improve efficiency and reduce cost, besides several drug developments and testing. High rate of attrition in drug development in the last two decades, especially when the drug reaches the later stages of development, is a major concern for the pharmaceutical industry. As a result, the heavy cost on research and development is incurred exceedingly on the pharmaceutical company. Thus, the pharmaceutical industry is constantly in the need of finding reasons for attrition failures.
However, the adoption of in vitro ADME screening into drug discovery programs have reduced this drug failure up to an extent. In 1991, 40% of clinical trial failures were due to poor pharmacokinetics. By, 2000 this number was reduced to 10% and this happened with the advent of in vitro ADME. In vitro ADME has been widely accepted in the pharmaceutical industry and its value has been recognized in the last five years. Some new cellular models and techniques have expanded the market of in vitro toxicology and this market is expected to grow a CAGR of 15.3% from 2013 to 2018. The later stage attrition can be overcome by the advent and subsequent growth of the in vitro toxicology testing methods.
There are several advantages of the in vitro toxicology approach as it has improved the overall predictive quality because human cells are being used. Moreover, this method is cost effective and is less time consuming as compared to the animal testing methods. Earlier, the methods for predicting toxicity in humans were same for testing toxicity in animals, but there are many chemicals that are toxic to one and non toxic to another and vice versa. It creates a lot more confusion in the testing and development of new drugs. Thus, the testing that is been conducted on human cells gives better opportunity to understand and improve the predictions of toxicity in humans. Thus, these in vitro toxicology methods are likely to gain more importance in the forecasted period with the continuous advancements in technology.
Although the in vitro toxicity market is new, it has huge potential in the future. Technological development and new product launch in this field will play a major role in this industry. However, the absence of pharmaceutical giants in this sector provides better opportunity for the new entrants to establish themselves in the market. Therefore, the company ready to invest can enter this emerging market and is likely to be successful as the market offers high potential to the new players.
In the present scenario, in vitro methods are widely used in by all regulatory bodies and industries in safety assessment, risk evaluation and toxicity testing. The main idea behind using in vitro techniques over animal testing are the advantages associated with them. The in vitro method is mainly used to elucidate mechanisms of toxicity in a drug and its effect on the cell or tissue. The development of Ames Mutagenic Assay made the non-animal testing more popular as compared to animal testing.
Furthermore, the regulatory concerns and political barriers are further expected to boost this market. Ethical concerns related to animals are one of the key factors in many countries that are likely to drive this market. The regulations are strict for animal testing in the countries such as Europe and the companies operating in this region are bound to ignore and move away from animal testing and choose in vitro toxicology testing for several product developments and research areas. Similarly, other emerging nations of Asia are also expected to follow suit and thus lead to better and rapid growth of in vitro testing methods in these regions.  Also, better economic conditions in this region will be highly supporting in adoption of this new technology and thus new developments in the pharmaceutical, chemicals, cosmetics and food industries will emerge rapidly in the future.
This report covers global In vitro toxicity testing market along with their types and packaging. It also covers the performance of In vitro toxicity testing types and application in different regions of the world namely, North America, Europe, Asia and RoW (Rest of the World) along with their sub-segments. Moreover, the report provides in-depth analysis of In vitro toxicity testing types and application with their market estimated and forecast from 2011 to 2018, along with their compound annual growth rate from 2013 to 2018.
The application of cosmetics and household industry, pharmaceutical industry, food industry and chemical industry has been covered in this report providing their market estimates and forecast from 2011 to 2018. Furthermore, the three main segments of In vitro toxicity testing, i.e., by application, by type and by end use in detail, are covered with their sub segment break down. Under the In vitro toxicity testing type segment, market estimations have been included for In vitro toxicity testing by absorption, by dose and by toxic substances with their sub-segments. The detailed analysis of these segments along with their estimates and forecast has been provided in this report. The drivers, restraints and opportunities concerning the In vitro toxicology testing market have been thoroughly covered in this report along with their impact analysis and this would be highly helpful in taking corporate strategic decisions related to In vitro toxicity testing market.
This report also provides company profiles of the major players in this industry. Our company profile includes company and financial overview, business strategies adopted by the companies, SWOT analysis and their recent developments which can help in assessing the competition in the market. Some of the major companies included in this report include Accelrys Software Inc., Apredica (Acquired By Cyprotex), Bio-Rad Laboratories, Charles River,Laboratories International Inc., Covance Inc., Gene Logic Inc., In Vitro Technologies, Mattek Corporation, Molecular Toxicology Inc., MB Research Laboratories, RTI Health Solutions, SBW Ltd., Xenobiotic Detection Systems (XDS) and Xenometrix.
We have used secondary research for deriving our market numbers for each segment of the research report and further validated our analysis with C-level executives of major companies operating in the In vitro toxicity testing market through the means of primary research to finally come up with our results. This research is specially designed to estimate and analyze the performance In vitro toxicity testing in global scenario. This research provides in-depth analysis of In vitro toxicity testing market sales, trend analysis by segments and demand by geography. The report covers all the major product type and application segments of the In vitro toxicity testing market and provides in-depth analysis, historical data and statistically refined forecast for the segments covered. The study presents a comprehensive assessment of the stakeholder strategies and winning imperatives for them by segmenting the global In vitro toxicity testing market as below:
In Vitro Toxicity Testing Market by End Use
  • Cosmetics and Household Products 
  • Pharmaceutical Industry 
  • Food Industry 
  • Chemicals Industry
In Vitro Toxicity Testing Market by Application
  • In Vitro Toxicity Testing Methods
  • Cytotoxicity Essays Uses for In Vitro Toxicity Testing
In Vitro Toxicity Market by Type
By Absorption
  • Distribution
  • Metabolism
  • Excretion
By Dose
  • Dose Response
  • Threshold Response
By Toxic Substances
  • Toxicant
  • Toxin 
  • Acute And Chronic Toxicity
  • Toxicokinetics
The geographies covered in this report include: 
  • North America
  • Europe 
  • Asia 
  • Rest of the World.

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In Vitro Toxicity Testing Market

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