Global Immune Repertoire Sequencing Market: Introduction

Immune repertoire is the sum of T cell receptors and B cell receptors that make an organism's adaptive immune system. It is extensively used in biomarker discovery to improve the success rate and cost-effectiveness of rational drug development. Advancements in next generation sequencing (NGS) have facilitated the development of a prevailing new technology known as immune repertoire sequencing for probing the complimentary determining region of these receptors. Immune repertoire sequencing targets T and B-lymphocytes and utilizes the 5’ Rapid Amplification of cDNA Ends (RACE) Technology.

Global Immune Repertoire Sequencing Market: Trends, Drivers, Restraints

  • Increase in government support for pharmacogenomics-based drug recovery is the major driver of the global immune repertoire sequencing market. Additionally, rapid rise in numerous therapeutic areas such as infectious diseases, cardiology, oncology, and pain management boosts the growth of the global market.
  • Agreements & partnerships among manufacturers is another key factor projected to contribute to the growth of the global immune repertoire sequencing market during the forecast period. For instance, in March 2018, ArcherDX and Ambry Genetics announced a partnership agreement to develop promising and innovative immunotherapies.
  • Increase in demand for personalized medicine is expected to propel the global immune repertoire sequencing market in the next few years, as personalized medicine uses an individual’s genetic makeup to direct the decisions made about the prevention, diagnosis, and cure of diseases.
  • Launch of novel products by key players and advancements in research & development are likely to fuel the growth of the global immune repertoire sequencing market in the near future. In 2017, ArcherDX launched Archer Immunoverse B Cell Receptor (BCR) assays to characterize the human B cell repertoire. According to a study published by Cold Spring Harbor Laboratory in 2017, researchers from the Stanford University applied immune repertoire sequencing to identify disease-related signatures in the immune systems of patients with systemic sclerosis-related pulmonary hypertension, which is a rare chronic autoimmune disease that affects the connective tissue. Hence, increase in research on immune repertoire sequencing is projected to augment the global immune repertoire sequencing market.
  • However, distinctive biological variations from the errors and the bias introduced in various different steps act as major restraints of the global immune repertoire sequencing market. Moreover, differences of data generation and processing in different laboratories are anticipated to hamper the growth of the global immune repertoire sequencing market during the forecast period.

COVID -19 Impact on Global Immune Repertoire Sequencing Market

  • The COVID-19 pandemic has had a significant effect on the global immune repertoire sequencing market due to undermining clinical trials, inadequate supply chain management & raw material storage, and patient incompliance. Moreover, decline in funding by governments due to the pandemic has negatively affected the global immune repertoire sequencing market.

North America to Dominate Global Immune Repertoire Sequencing Market

  • In terms of region, North America is expected to dominate the global immune repertoire sequencing marked during the forecast period. The U.S. is likely to dominate the market in the region due to increase in demand for immunotherapy for cancer and other infectious diseases.
  • Europe was the second largest market for immune repertoire sequencing in 2020 due to funding by governments and increase in health care expenditure
  • The market in Asia Pacific, primarily in Japan and China, is projected to witness significant growth due to international collaborations for immune repertoire sequencing and developments.
  • However, Middle East & Africa is expected to be the least attractive market for immune repertoire sequencing due to lack of skilled personnel and Internet access limitations for data analysis

Key players in the global immune repertoire sequencing market are:

  • Adaptive Biotechnologies
  • Thermo Fisher Scientific
  • Pacific Biosciences
  • Illumina, Inc.
  • Juno Therapeutics
  • F. Hoffmann La-Roche AG
  • CD Genomics
  • QIAGEN N.V.
  • Atreca, Inc.
  • Oxford Nanopore Technologies, Ltd.
  • ArcherDX, Inc.
  • Abvitro (Now Juno Therapeutics)
  • Agilent Technologies
  • Irepertoire, Inc.
  • Takara Bio, Inc.
  • Others

Global Immune Repertoire Sequencing Market - Research Scope

Global Immune Repertoire Sequencing Market, by Type

  • Pyro Sequencing
  • Dye-terminating sequencing
  • Others

Global Immune Repertoire Sequencing Market, by Product

  • Assay, Kits, and Reagent
    • TCR Kits
      • Human TCR Kits
      • Mouse TCR Kits
    • BCR Kits
      • Human BCR Kits
      • Mouse BCR Kits
  • Instrument
    • NGS
    • PCR
  • Analytical Software
    • TCR Analysis Solutions
    • BCR Analysis Solutions
    • TCR & BCR Analysis Solutions
  • Services
    • Pre-sequencing Services
    • Sequencing Services
    • Data Analysis Services

Global Immune Repertoire Sequencing Market, by Application

  • Biomarker Discovery
  • Asthma and Allergy Research
  • Immunodeficiency Identification
  • Cancer Immunotherapy
  • Infectious Disease Research
  • Vaccine Development
  • Autoimmune Disease

Global Immune Repertoire Sequencing Market, by End-user

  • Diagnostic Labs
  • Research Institutes
  • Pharmaceutical & Biotech Companies
  • Others

Global Immune Repertoire Sequencing Market, by Region

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • U.K
    • France
    • Italy
    • Spain
    • Rest of Europe
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia & New Zealand
    • Rest of Asia Pacific
  • Latin America
    • Brazil
    • Mexico
    • Rest of Latin America
  • Middle East & Africa
    • GCC Countries
    • South Africa
    • Rest of Middle East & Africa

This intelligence report by TMR is the outcome of intense study and rigorous assessment of various dynamics shaping the growth of the market. TMR nurtures a close-knit team of analysts, strategists, and industry experts who offer clients tools, methodologies, and frameworks to make smarter decisions. Our objective, insights, and actionable analytics provide CXOs and executives to advance their mission-critical priorities with confidence.

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All our insights and perspectives are broadly based on 4 Pillars or Stages: ASBC-S, which offer an elaborate and customizable framework for the success of an organization. The essence and the roles of these in organizational successes are highlighted below:

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The study presents scrutiny of region-specific consumer and technology trends, including the most recent industry dynamics. These broadly cover but not limited to

  • North America, South America, and the Americas
  • Asia Pacific and Japan
  • Europe
  • Latin America
  • Middle East and Africa

The study offers data-driven insights and guidance of several aspects. Some of the more notable questions are:

  • What are the major recent trends that can influence the product life cycle and the RoI?
  • Which regulatory trends shape corporate-level, business-level, and functional-level strategies?
  • Which micromarketing initiatives of leading players will bring in investments?
  • What can be the best framework and tools for PESTLE analysis?
  • Which regions will witness rise in new opportunities?
  • Which are the game-changing technologies being used to capture new revenue streams in the near future?
  • Which operational and tactical frameworks are being adopted by various players in gaining customer loyalty?
  • What is the current and expected intensity of competition the market in the near future?

Disclaimer: This market research study is an ongoing effort and extreme care has been taken to maintain the highest levels of accuracy at all stages. However, in the light of the rapidly evolving business dynamics, some region-specific or other segment-specific changes may take time to be part of the study.

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Immune Repertoire Sequencing Market