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Eosinophilic esophagitis is a chronic immunological disorder of the gastrointestinal system, in which a large number of eosinophils (a particular type of white blood cells) are present in the esophagus. The esophagus is a tube that carries food from the mouth to the stomach. Eosinophilic esophagitis is also known as allergic esophagitis. Eosinophils are a part of the body’s immune system. They play a key role in immune regulation and protect body against certain infections. Their accumulation at a particular location in the body is a sign of presence of allergic diseases. The most common symptoms of eosinophilic esophagitis include vomiting, stomachache, chest pain, difficulty in swallowing (dysphagia), and food getting trapped in the throat (impaction). The exact cause of the disease is not known; however, production and accumulation of a large number of eosinophils at a particular location may be caused by allergenic immune responses to environmental proteins (allergens) or particular foods. Other causes include acid reflux, certain antibiotic medications, and radiation therapy. The condition is known to occur in children as well as adults and is more prevalent in men than women. People living in cold or dry climate, those having family history of eosinophilic esophagitis, and those suffering from other allergies or asthma are more susceptible to eosinophilic esophagitis. Diagnosis of eosinophilic esophagitis involves esophagogastroduodenoscopy biopsy, endoscopy, or radiology. Efficacy and the choice of treatment for eosinophilic esophagitis depend on family desire to treat the symptoms and the cause of the disease while compromising a few aspects of quality of life. Treatment for eosinophilic esophagitis includes dietary management and pharmacological therapy. The initial approach may involve dietary modification such as exclusion of food that causes allergy, medical therapy, and mechanical esophageal dilation.

The global market for eosinophilic esophagitis can be segmented based on therapy type and geography. Based on therapy type, the global eosinophilic esophagitis market has been segmented as proton pump inhibitors, corticosteroids (fluticasone and budesonide), immunomodulators (azathioprine), and biologics (mepolizumab and infliximab). However, in severe cases, need for mechanical dilation is considered, which is fulfilled by passing dilators through the mouth up to the esophagus, gently causing expansion of the esophagus. The biologics segment is expected to expand during the forecast period, due to more efficacy of biologics and high number of ongoing clinical trials for them. Increase in the incidence of eosinophilic esophagitis, rise in the research and development expenditure, and rise in awareness about eosinophilic esophagitis are factors that fuel the eosinophilic esophagitis market. However, high cost of therapy, lack of confidence of pipeline molecules, and high possibility of the disease going undiagnosed or misdiagnosed with other digestive complications are factors that restrain the market for eosinophilic esophagitis.

Geographically, the global eosinophilic esophagitis market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The market in North America is expected to expand significantly during the forecast period, followed by Europe. Growth of the market in North America is attributable to the increase in demand for advance treatment options, rise in health care expenditure, and high diagnosis rate in the region. Asia Pacific is an emerging market for eosinophilic esophagitis, due to developing health care infrastructure, increasing government expenditure, growing patient awareness, and rising number of patients suffering from eosinophilic esophagitis. However, high cost of therapy and lack of patient education are factors restraining the eosinophilic esophagitis market in regions such as Middle East & Africa and Latin America.

Some of the key players operating in the global eosinophilic esophagitis market are Axcan Pharma, Inc., Celgene Corporation, Regeneron Pharmaceuticals, Inc., Shire Plc,  Meritage Pharma, Inc., Novartis International AG, Receptos, Inc., Dr. Falk Pharma GmbH, and Teva Pharmaceuticals Industries Limited.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Eosinophilic Esophagitis Market