Single-stranded fragments of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are called DNA probes and RNA probes respectively. These DNA and RNA probes are short in length (usually 100-1000 bases long) capable of forming highly specific, non-covalent duplexes with complementary sequence of nucleic acid strand. Therefore, typical applications of these probes are in fluorescence in situ hybridization (FISH), microarray-based gene expression profiling or electrophoretic mobility shift assays (EMSA).
These DNA and RNA genetic probes have three important applications from a medical perspective: detection of specific nucleic acid sequences, detection of changes in nucleic acid sequences(mutation) and detection of tandem repeat sequences (30-50 base pairs). These probes are designed to detect and identify various infectious agents such as bacteria, protozoa and viruses. Detection of genetic mutation using DNA and RNA probe is also of diagnostic importance in hereditary diseases such as cystic fibrosis, muscular dystrophy, phenylketonuria and sickle cell anemia. The detection of tandem repeat sequences is of vital use in forensic science and paternity testing.
DNA or RNA probes are categorized either as radioactive probes or as non-radioactive probes based on the nature of material used for labelling. Radioactive probes most commonly involve enzymatic incorporation of 32P, 33P, or 35S. Non-radioactive probesinvolve attaching the probe either to an enzyme (alkaline phosphatase or horseradish peroxidase), an antibody directed against an enzyme, fluorophore, or to an achemifluorescent substrate. Alternatively, these probes can be labeled with biotin, making it detectable by a streptavidin and avidin enzyme conjugate.
Some of the major players in the global DNA and RNA probes market are Amersham Life Sciences, Inc., Clontech Laboratories, Inc., Epicentre Technologies, FMC Corporation, GE Healthcare, Genosys Biotechnologies, Inc., IBA GmbH, IDEXX Laboratories, Inc., Kamiya Biomedical Co., Oncor, Inc., Operon, Inc., Sigma-Aldrich Co. LLC., Signet Laboratories, Inc., and Vysis, Inc.
This research report analyzes this market depending on its market segments, major geographies, and current market trends. Geographies analyzed under this research report include
- North America
- Asia Pacific
- Rest of the World
This report provides comprehensive analysis of
- Market growth drivers
- Factors limiting market growth
- Current market trends
- Market structure
- Market projections for upcoming years
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.
Reasons for Buying this Report
- This report provides pin-point analysis for changing competitive dynamics
- It provides a forward looking perspective on different factors driving or restraining market growth
- It provides a technological growth map over time to understand the industry growth rate
- It provides a seven-year forecast assessed on the basis of how the market is predicted to grow
- It helps in understanding the key product segments and their future
- It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors
- It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments
- It provides distinctive graphics and exemplified SWOT analysis of major market segments
Note : All statements of fact, opinion, or analysis expressed in reports are those of the respective analysts. They do not necessarily reflect formal positions or views of Transparency Market Research.