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The Acquired Immune Deficiency Syndrome (AIDS) is caused by a virus know as Human Immunodeficiency Virus (HIV). This virus attacks the immune system (CD4 cells) and exposes an individual to host opportunistic infections. The infections acquired by an individual when his immune defenses are low are termed as opportunistic infections. These infections generally do not affect healthy persons while the immunocompromised patients are the softest targets for such infections. The attack of these infections was more frequent and more severe in the past before beginning of the widespread use of potent combination of antiretroviral therapy (ART). However, with the advent of ARTs there has been noteworthy reduction in mortality rate of HIV patients and reduction in risk of AIDS-related opportunistic infections.
 
The most common opportunistic infections in HIV positive people are Candidiasis, Cytomegalovirus (CMV), Cryptococcosis, Cryptosporidiosis, Mycobacterium avium complex (MAC), Mycobacterium tuberculosis (TB), Pneumocystis pneumonia (PCP), Progressive multifocal leukoencephalopathy (PML) and Toxoplasmosis (Toxo). A person’s T cell or CD4 count determines his/her risk for certain opportunistic infections. It is therefore necessary that medications are used to boost the CD4 cells. The use adoption of standard antiretroviral therapy (ART) consisting of combination of at least three antiretroviral (ARV) drugs have been proven beneficial in suppressing the HIV virus and halting the progressing of HIV disease.
 
The very first class of drugs used as antiretroviral therapy was nucleoside reverse transcriptase inhibitors (also called NRTIs). The major drugs in this class include zidovudine, didanosine, stavudine, lamivudine, abacavir, tenofovir, emtricitabine. Non-nucleoside reverse transcriptase inhibitors and integrase inhibitors constitute other classes of ART drugs. If the patient population is not engaged in ART therapy or other preventive measures such as vaccination programs and prophylaxis, AID-related opportunistic infections are bound to occur. Some of the major AIDS-related opportunistic infections and their recommended treatment drugs include Pneumocystis Jiroveci Pneumonia (Trimethoprim-sulfamethoxazole), Toxoplasma gondii Encephalitis (pyrimethamine, sulfadiazine and leucovorin), Cryptosporidiosis (Paromomycin), Mycobacterium tuberculosis Disease (Isoniazid, rifampin, ethambutol, pyrazinamide and DOTS therapy), Mycobacterium avium Complex Disease (Clarithromyci and azithromycin),and bacterial pneumonia (levofloxacin, moxifloxacin, or gatifloxacin).
 
On the basis of geography, the global AIDS-related opportunistic infections market is segmented into six major regions, namely, North America, Europe, Asia Pacific, Middle East, Africa and Latin America. The highly priced branded drugs are sold in markets such as North America and Europe which formulates them into global leader in the overall AIDs-related market. Despite the availability of antiretroviral therapy in the developed nations such as United States, the AIDS-related opportunistic infections are causing significant morbidity and mortality. The disease is more serious in other regions, particularly in Africa. Of the estimated 34.2 million HIV-infected individuals worldwide, more than 22.9 million people are from Sub-Saharan Africa and represent continuous demand for HIV/AIDS treatment drugs. The patients in these low- and middle-income countries of other regions were earlier deprived of the antiretroviral therapy or HIV treatment due to high costs of therapy. However, with the increasing production of generic drugs in countries like India, the treatment cost has reduced drastically and have helped in improved uptake of antiretroviral therapy in these countries. In 2011, more than 8 million received ARV therapy which represents significant growth in supply of this therapy drugs. The WHO recommendation for ARV usage for prevention of HIV infection, particularly for pregnant women, young children and other population with HIV risk is expected to further drive the drugs market for AID-related opportunistic infections.
 
Some of major companies in the global AIDS-related opportunistic infections market include ViiV Healthcare, Gilead Sciences, Inc., Bristol-Myers Squibb Co., Merck & Co., Johnson & Johnson, Pfizer, Inc., GlaxoSmithKline plc, and Janssen Therapeutics.

This study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.

Our key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:

  • Customer Experience Maps
  • Insights and Tools based on data-driven research
  • Actionable Results to meet all the business priorities
  • Strategic Frameworks to boost the growth journey

The study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.

The following regional segments are covered comprehensively:

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • The Middle East and Africa

The EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.

Below is a snapshot of these quadrants.

1. Customer Experience Map

The study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.

2. Insights and Tools

The various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.

3. Actionable Results

The findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.

4. Strategic Frameworks

The study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.

The report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:

1. What can be the best investment choices for venturing into new product and service lines?

2. What value propositions should businesses aim at while making new research and development funding?

3. Which regulations will be most helpful for stakeholders to boost their supply chain network?

4. Which regions might see the demand maturing in certain segments in near future?

5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?

6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?

7. Which government regulations might challenge the status of key regional markets?

8. How will the emerging political and economic scenario affect opportunities in key growth areas?

9. What are some of the value-grab opportunities in various segments?

10. What will be the barrier to entry for new players in the market?

Note: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.

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Aids Related Opportunistic Infections Market

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