Live cell imaging (LCI) is changing the approach in which biologists study proteins, cells, molecular interactions and a multitude of processes. LCI techniques are allowing the scientists to monitor cellular processes and internal structures in real time, and over time. Understanding dynamic processes and cellular structures is serious to addressing several queries of cell biology. The observation of vital changes is offering in-depth understanding into the operations of a cell than an image provided by imaging studies of fixed cells. Additionally, meanwhile live cell imaging is less liable to trial artifacts; it generally offers more valid and appropriate information than does fixed cell microscopy. The study of living cells through pictures developed from imaging systems such as microscopes and screening system that is high content is termed as live cell imaging. LCI used by the scientists to give an enhanced view of biological function through the study of cellular dynamics. This information is vital in research regions including genetics, in drug discovery, neurobiology, immunology, cytology, and microbiology.
The global LCI market segmented, based on products, technologies, applications, and regions. Based on products classification of LCI is equipment, software, and consumables. The further classification of equipment is microscopes, image capturing devices, and standalones system and cell analyzers. Currently microscope has the largest share in the equipment. Consumable differentiation is as reagents, media, and assay kits. The assay kit has accounted for the major share in consumable market. Technology market is segmented into Fluorescence recovery after photo bleaching (FRAP), Forster resonance energy transfer (FRET), Total internal reflection fluorescence microscopy (TIRF), Time-domain Fluorescence Lifetime Imaging Microscopy (TD-FLIM), Photo activated localization microscopy (PALM) and multiphoton excitation microscopy (MPE).Based on application it is classified as chemotaxis, angiogenesis, migration or wound healing and cell culture under flow.
The high content screening technology in drug discovery, large funding by the government for cell based research and the increasing incidences of cancer are the factors responsible to drive the market for LCI. However, the shortage of skilled professional and huge cost of high content screening system can hinder the growth of LCI market.
Some of the major players in the LCI market are Carl Zeiss AG, Leica Microsystems, Molecular Devices, LCC, Nikon Corporation, PerkinElmer, Inc. Becton, Dickinson and Company, GE Healthcare, Sigma-Aldrich Corporation, and Thermo Fisher Scientific, Inc.
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