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Published Date: 2015-05-29Number of Pages: 125

G-Protein Coupled Receptors (GPCRs) Market (Assay Type: cAMP Assays, Calcium Level Detection Assays, GTPγS Binding Assays, Reporter Gene Assays, Receptor Internalization Assays, and cGMP Assays; Therapeutic Areas: Cardiovascular System, Central Nervous System, Respiratory System, Immune System, Reproductive System, Oncology, and Others): Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2022


This report on G-protein coupled receptors (GPCRs) market studies the current as well as future prospects of the market globally. The stakeholders of this report include companies engaged in manufacturing and commercialization of GPCR assays, cell lines, and consumables and entrants that are planning to invest in the GPCRs market. This report comprises an elaborate executive summary, which includes a market snapshot providing overall information of various segments and sub-segments included in the study scope. This section also provides overall information and data analysis of the global GPCRs market with respect to the leading market segments based on types of products, applications and geographic regions.

The global GPCRs market has been segmented based on of assay type, therapeutic area, and geography. Based on assay type, the GPCRs market has been categorized into six major segments: cAMP assays, calcium level detection assays, GTPγS binding assays, reporter gene assays, receptor internalization assays, and cGMP assays. The market for these segments has been extensively analyzed based on of their effectiveness, usefulness, sales, and geographic presence. Market revenue in terms of USD million for the period between 2012 and 2022 along with the compound annual growth rate (CAGR %) from 2014 to 2022 are provided for all the segments, considering 2013 as the base year.

In terms of therapeutic areas, the market has been segmented into seven categories: cardiovascular system, central nervous system (CNS), respiratory system, immune system, reproductive system, oncology, and others (abdominal, urinary, orthopedics, etc.). Market revenue in terms of USD million for the period between 2012 and 2022 along with the compound annual growth rate (CAGR %) from 2014 to 2022 are provided for all the segments, considering 2013 as the base year.

The market overview section of the report explores market dynamics such as drivers, restraints, and opportunities that have strong impact on the GPCRs market currently and could influence the market in future as well. The market attractiveness analysis has been provided in the market overview section in order to explain the intensity of competition in the market across different geographies. Porter’s Five Forces analysis is also explained in this section to understand the GPCRs market considering different parameters that have an impact on the sustainability of the companies operating in the GPCRs market. The competitive scenario among different market players is evaluated through market share analysis in the competitive landscape section of the report. All these factors would help market players to take strategic decisions in order to strengthen their positions and expand their shares in the global market.

Geographically, the GPCRs market has been categorized into four regions: North America, Europe, Asia Pacific, and Rest of the World (RoW). Major geographic regions have been further divided into major national markets, viz. North America (the U.S. and Canada), Europe (Germany, the U.K., France, and Rest of Europe), and Asia Pacific (China, Japan, India, and Rest of Asia Pacific). Moreover, Rest of the World has been further subdivided into three regions: Latin America, the Middle East, and Africa. Market revenue in terms of USD million for the period between 2012 and 2022 along with the CAGR % from 2014 to 2022 are provided for all the regional and national markets considering 2013 as the base year.

The recommendations section included in the report would assist existing market players in expanding their market shares and new companies in establishing their presence in the global market. The report also profiles major players in the GPCRs market based on various attributes such as company overview, financial overview, business strategies, product portfolio, and recent developments. Major players profiled in this report include Thermo Fisher Scientific, Inc., EMD (Merck) Millipore, Becton, Dickinson and Company, PerkinElmer, Inc., Cisbio Bioassays, Enzo Life Sciences, Inc., DiscoveRx Corporation, Sigma-Aldrich Corporation, QIAGEN N.V., Promega Corporation, Abcam plc, and HD Biosciences Co. Ltd.

The global GPCRs market is segmented as follows:

GPCRs Market, by Assay Type
  • Calcium Level Detection Assays 
  • GTPγS Binding Assays 
  • cGMP Assays
  • Reporter Gene Assays 
  • Receptor Internalization Assay 
  • cAMP Assays 
GPCRs Market, by Therapeutic Area
  • Cardiovascular System
  • Central Nervous System
  • Respiratory System
  • Immune System
  • Reproductive System
  • Oncology
  • Others
GPCRs Market, by Geography
  • North America
    • U.S.
    • Canada
  • Europe
    • U.K.
    • Germany
    • France
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • Rest of Asia Pacific
  • Rest of the World (RoW)
    • Latin America
    • Middle East
    • Africa.


Chapter 1 Introduction
1.1 Report Description
1.2 Market Segmentation
1.3 Research Methodology
1.4 Assumptions

Chapter 2 Executive Summary
2.1 Market Snapshot: Global G-Protein Coupled Receptors (GPCRs) Market
2.2 Comparative Analysis: Global GPCRs Market Revenue, by Geography, 2013 & 2022 (Value %)

Chapter 3 Global G-Protein Coupled Receptors (GPCRs) Market Overview
3.1 Introduction
3.2 Market Drivers
      3.2.1 Rising Demand for Advanced/Improved GPCR Assays, Assay Systems and Platforms in Ever Growing Drug Discovery and ADME Toxicity Studies Worldwide
      3.2.2 High Prevalence and Incidence of Cardiovascular, Respiratory, and Reproductive Conditions along with Rising Occurrence of Cancers and Nervous System Disorders Globally
      3.2.3 Increased Government Initiatives and Partnerships/ Collaborations are Likely to Boost Demand for Technologically Advanced GPCR Assays and Assay Systems Worldwide
3.3 Market Restraints
      3.3.1 High Cost Involved in the Maintenance of Cell Lines and Costly Equipment and Instruments could Restrain Demand for GPCR Assays
3.4 Market Opportunities
      3.4.1 Development of Technologically Advanced GPCR Assays, Assay Systems and Assay Platforms
3.5 Porter’s Five Forces Analysis: Global GPCRs Market
      3.5.1 Bargaining Power of Suppliers
      3.5.2 Bargaining Power of Buyers
      3.5.3 Threat of Substitutes
      3.5.4 Threat of New Entrants
      3.5.5 Competitive Rivalry
3.6 Value Chain Analysis: GPCRs Market
3.7 Market Attractiveness Analysis: Global GPCRs Market, by Geography
3.8 Competitive Landscape
      3.8.1 Market Share Analysis, by Key Players: Global GPCRs Market, 2013 (Value %)

Chapter 4 Global G-Protein Coupled Receptors (GPCRs) Market, by Assay Type
4.1 Introduction
      4.1.1 Global GPCRs Market Revenue, by Assay Type, 2012 – 2022 (USD Million)
      4.1.2 Comparative Analysis: Global GPCRs Market Revenue, by Assay Type, 2013 & 2022 (Value %)
4.2 Calcium Level Detection Assays
      4.2.1 Global Calcium Level Detection Assays Market Revenue, 2012 – 2022 (USD Million)
4.3 GTPγS Binding Assays
      4.3.1 Global GTPγS Binding Assays Market Revenue, 2012 – 2022 (USD Million)
4.4 cGMP Assays
      4.4.1 Global cGMP Assays Market Revenue, 2012 – 2022 (USD Million)
4.5 Reporter Gene Assays
      4.5.1 Global Reporter Gene Assays Market Revenue, 2012 – 2022 (USD Million)
4.6 Receptor Internalization Assays
      4.6.1 Global Receptor Internalization Assays Market Revenue, 2012 – 2022 (USD Million)
4.7 cAMP Assays
      4.7.1 Global cAMP Assays Market Revenue, 2012 – 2022 (USD Million)

Chapter 5 Global G-Protein Coupled Receptors (GPCRs) Market, by Therapeutic Areas
5.1 Introduction
      5.1.1 Global GPCRs Market Revenue, by Therapeutic Areas, 2012 – 2022 (USD Million)
      5.1.2 Comparative Analysis: Global GPCRs Market Revenue, by Therapeutic Areas, 2013 & 2022 (Value %)
5.2 Cardiovascular System
      5.2.1 Global GPCR Assays in Cardiovascular Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.3 Central Nervous System (CNS)
      5.3.1 Global GPCR Assays in CNS Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.4 Respiratory System
      5.4.1 Global GPCR Assays in Respiratory Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.5 Immune System
      5.5.1 Global GPCR Assays in Immune System Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.6 Reproductive System
      5.6.1 Global GPCR Assays in Reproductive System Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.7 Oncology
      5.7.1 Global GPCR Assays in Oncology Therapeutics Market Revenue, 2012 – 2022 (USD Million)
5.8 Other Therapeutic Areas
      5.8.1 Global GPCR Assays in Other Therapeutic Areas Market Revenue, 2012 – 2022 (USD Million)

Chapter 6 Global G-Protein Coupled Receptors (GPCRs) Market, by Geography
6.1 Introduction
      6.1.1 Global GPCRs Market Revenue, by Geography, 2012 – 2022 (USD Million)
6.2 North America
      6.2.1 North America GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
      6.2.2 United States
              6.2.2.1 United States GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.2.3 Canada
              6.2.3.1 Canada GPCRs Market Revenue, 2012 – 2022 (USD Million)
6.3 Europe
      6.3.1 Europe GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
      6.3.2 The United Kingdom
              6.3.2.1 United Kingdom GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.3.3 Germany
              6.3.3.1 Germany GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.3.4 France
              6.3.4.1 France GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.3.5 Rest of Europe
              6.3.5.1 Rest of Europe GPCRs Market Revenue, 2012 – 2022 (USD Million)
6.4 Asia Pacific
      6.4.1 Asia Pacific GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
      6.4.2 China
             6.4.2.1 China GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.4.3 Japan
             6.4.3.1 Japan GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.4.4 India
             6.4.4.1 India GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.4.5 Rest of Asia Pacific
              6.4.5.1 Rest of Asia Pacific GPCRs Market Revenue, 2012 – 2022 (USD Million)
6.5 Rest of the World (RoW)
      6.5.1 Rest of the World GPCRs Market Revenue, by Geography, 2012 – 2022 (USD Million)
      6.5.2 Latin America
             6.5.2.1 Latin America GPCRs Market Revenue, 2012 – 2022 (USD Million)      
      6.5.3 Middle East
              6.5.3.1 Middle East GPCRs Market Revenue, 2012 – 2022 (USD Million)
      6.5.4 Africa
             6.5.4.1 Africa GPCRs Market Revenue, 2012 – 2022 (USD Million)

Chapter 7 Recommendations
7.1 Develop Technologically Advanced GPCR Assays, Assay Systems and Platforms to Create Future Growth Opportunities
7.2 Target Emerging Economies of the World for Higher Benefits
7.3 Collaborate to Strengthen Market Presence

Chapter 8 Company Profiles
8.1 Abcam plc
      8.1.1 Company Overview
      8.1.2 Financial Overview
      8.1.3 Product Portfolio
      8.1.4 Business Strategies
      8.1.5 Recent Developments
8.2 Becton, Dickinson and Company
      8.2.1 Company Overview
      8.2.2 Financial Overview
      8.2.3 Product Portfolio
      8.2.4 Business Strategies
      8.2.5 Recent developments
8.3 Cisbio Bioassays
      8.3.1 Company Overview
      8.3.2 Financial Overview
      8.3.3 Product Portfolio
      8.3.4 Business Strategies
      8.3.5 Recent Developments
8.4 DiscoveRx Corporation
      8.4.1 Company Overview
      8.4.2 Financial Overview
      8.4.3 Product Portfolio
      8.4.4 Business Strategies
      8.4.5 Recent Developments
8.5 EMD Millipore Corporation
      8.5.1 Company Overview
      8.5.2 Financial Overview
      8.5.3 Product Portfolio
      8.5.4 Business Strategies
      8.5.5 Recent Developments
8.6 Enzo Life Sciences, Inc.
      8.6.1 Company Overview
      8.6.2 Financial Overview
      8.6.3 Product Portfolio
      8.6.4 Business Strategies
      8.6.5 Recent Developments
8.7 HD Biosciences Co. Ltd.
      8.7.1 Company Overview
      8.7.2 Financial Overview
      8.7.3 Product Portfolio
      8.7.4 Business Strategies
      8.7.5 Recent Developments
8.8 PerkinElmer, Inc.
      8.8.1 Company Overview
      8.8.2 Financial Overview
      8.8.3 Product Portfolio
      8.8.4 Business Strategies
      8.8.5 Recent Developments
8.9 Promega Corporation
      8.9.1 Company Overview
      8.9.2 Financial Overview
      8.9.3 Product Portfolio
      8.9.4 Business Strategies
      8.9.5 Recent Developments
8.10 QIAGEN
      8.10.1 Company Overview
      8.10.2 Financial Overview
      8.10.3 Product portfolio
      8.10.4 Business Strategies
      8.10.5 Recent Developments
8.11 Sigma-Aldrich Corporation
      8.11.1 Company Overview
      8.11.2 Financial Overview
      8.11.3 Product Portfolio
      8.11.4 Business Strategies
      8.11.5 Recent Developments
8.12 Thermo Fisher Scientific, Inc.
      8.12.1 Company Overview
      8.12.2 Financial Overview
      8.12.3 Product portfolio
      8.12.4 Business Strategies
      8.12.5 Recent Developments

List of Figures

FIG. 1 G-Protein Coupled Receptors (GPCRs): Market Segmentation
FIG. 2 Global GPCRs Market Revenue, by Assay Type, 2013 (USD Million)
FIG. 3 Global GPCRs Market Revenue, by Therapeutic Areas, 2013 (USD Million)
FIG. 4 Comparative Analysis: Global GPCRs Market Revenue, by Geography, 2013 & 2022 (Value %)
FIG. 5 Porter’s Five Forces Analysis: Global GPCRs Market
FIG. 6 Value Chain Analysis: Global GPCRs Market
FIG. 7 Market Attractiveness Analysis: Global GPCRs Market, by Geography, 2013
FIG. 8 Market Share Analysis, by Key Players: Global GPCRs Market, 2013 (Value %)
FIG. 9 Comparative Analysis: Global GPCRs Market Revenue, by Assay Type, 2013 & 2022 (Value %)
FIG. 10 Global Calcium Level Detection Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 11 Global GTPγS Binding Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 12 Global cGMP Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 13 Global Reporter Gene Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 14 Global Receptor Internalization Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 15 Global cAMP Assays Market Revenue, 2012 – 2022 (USD Million)
FIG. 16 Comparative Analysis: Global GPCRs Market Revenue, by Therapeutic Areas, 2013 & 2022 (Value %)
FIG. 17 Global GPCR Assays in Cardiovascular Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 18 Global GPCR Assays in CNS Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 19 Global GPCR Assays in Respiratory Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 20 Global GPCR Assays in Immune System Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 21 Global GPCR Assays in Reproductive System Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 22 Global GPCR Assays in Oncology Therapeutics Market Revenue, 2012 – 2022 (USD Million)
FIG. 23 Global GPCR Assays in Other Therapeutic Areas Market Revenue, 2012 – 2022 (USD Million)
FIG. 24 United States GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 25 Canada GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 26 United Kingdom GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 27 Germany GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 28 France GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 29 Rest of Europe GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 30 China GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 31 Japan GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 32 India GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 33 Rest of Asia Pacific GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 34 Latin America GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 35 Middle East GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 36 Africa GPCRs Market Revenue, 2012 – 2022 (USD Million)
FIG. 37 Abcam plc: Annual Revenue, 2011 – 2013 (USD Million)
FIG. 38 BD Biosciences: Annual Revenue, 2011 – 2013 (USD Million)
FIG. 39 EMD Millipore Corporation: Annual Revenue, 2011 – 2013 (USD Million)
FIG. 40 Enzo Life Sciences, Inc.: Annual Revenue, 2011 – 2013 (USD million)
FIG. 41 PerkinElmer, Inc.: Annual Revenue, 2011 – 2013 (USD Million)
FIG. 42 QIAGEN: Annual Revenue, 2011 – 2013 (USD Million)
FIG. 43 Sigma-Aldrich Corporation: Annual Revenue, 2011 – 2013 (USD million)
FIG. 44 Thermo Fisher Scientific, Inc.: Annual Revenue, 2011 – 2013 (USD Million)

List of Tables

TABLE 1 Market Snapshot: Global G-Protein Coupled Receptors (GPCRs) Market
TABLE 2 Global GPCRs Market Revenue, by Assay Type, 2012 – 2022 (USD Million)
TABLE 3 Global GPCRs Market Revenue, by Therapeutic Areas, 2012 – 2022 (USD Million)
TABLE 4 Global GPCRs Market Revenue, by Geography, 2012 – 2022 (USD Million)
TABLE 5 North America GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
TABLE 6 Europe GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
TABLE 7 Asia Pacific GPCRs Market Revenue, by Country, 2012 – 2022 (USD Million)
TABLE 8 Rest of the World GPCRs Market Revenue, by Geography, 2012 – 2022 (USD Million)


GPCRs market comprises assays and kits that aid in drug discovery and development. GPCRs is a large family of cell surface receptors that respond to a diverse range of external stimulus and play a major role in modern pharmacology due to their significant function in cell communication. More than 30% of the drugs available in the global market target GPCRs and most of the drugs that are currently under clinical and preclinical studies target this highly studied receptor protein. A wide range of GPCR assays such as cAMP assays, calcium level detection assays, etc. have been developed over the years that have helped in drug discovery processes worldwide.

The global GPCRs market has been categorized based on six assay types: calcium level detection assays, GTPγS binding assays, cGMP assays, reporter gene assays, receptor internalization assays, and cAMP assays. The cAMP assays segment held the largest share of the market, followed by the calcium level detection assays segment in 2013. Key factors attributed to the high growth of this segment are increasing demand for cAMP assays in high throughput screening (HTS) and various other major drug discovery platforms, introduction of advanced cAMP assays and wide applicability of these assays in a range of therapeutic applications.

In terms of therapeutic areas, the market has been segmented into seven categories: cardiovascular system, central nervous system (CNS), respiratory system, immune system, reproductive system, oncology, and others (abdominal, urinary, orthopedics, etc.). Oncology was the largest segment of the global GPCRs market in 2013. The segment includes several prime cancer therapeutic areas such as breast cancer, leukemia, lung cancer, cervical cancer, prostate cancer, and/or several other malignant tumorous outgrowths. High prevalence and increasing incidence of several of these cancers are expected to drive the growth of the segment in the near future. 

Geographically, the GPCRs market has been categorized into four regions: North America, Europe, Asia Pacific, and Rest of the World (RoW). North America dominated the global GPCRs market followed by Europe owing to high geriatric population and rising obesity-related diseases due to unhealthy lifestyle habits, unhealthy eating habits, excessive alcohol intake and smoking leading to cardiovascular diseases. The regions also account for high number of research and development activities for the development of highly effective therapeutic drugs, which would require increased usage of GPCR assays. Asia Pacific was the third largest market for GPCRs, and is expected to register the fastest CAGR during the forecast period. Large untapped opportunities, improving health care infrastructure, rising research and development activities, expansion of large pharmaceutical manufacturers and CROs, and rising geriatric population in the region would contribute to the growth of the market.

Thermo Fisher Scientific, Inc., EMD Millipore, Becton, Dickinson and Company, PerkinElmer, Inc., Cisbio Bioassays, Enzo Life Sciences, Inc., DiscoveRx Corporation, Sigma-Aldrich Corporation, QIAGEN N.V., Promega Corporation, Abcam plc, and HD Biosciences Co. Ltd. are the major players operating in the global GPCRs market. Most of these players constantly innovate and develop technologically advanced and/or improved GPCR assays and assay systems to maintain their positions in the global market. For instance, Tango GPCR Assay System and GeneBLAzer Validated Functional Assays from Thermo Fisher Scientific, Inc., ACTOne cAMP Assay from Becton, Dickinson and Company and Cyclic AMP cell-based assay kits from Cisbio Bioassays, would help in capitalizing on future customer preferences. These market players also collaborate with other companies as well as various global organizations through long-term agreements to develop innovative, technologically advanced or improved GPCR assays, assay platforms and systems.

g-protein-coupled-receptors-market


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